The temporal relationship of thresholds between muscle activity and ventilation during bicycle ramp exercise in community dwelling elderly males
[Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus femoris, biceps femoris long head and gastrocnemius lateral head muscles during ramp cycling exercise in elderly males. [Subjects and Method...
Saved in:
| Published in | Journal of Physical Therapy Science Vol. 28; no. 11; pp. 3213 - 3219 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Japan
The Society of Physical Therapy Science
2016
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0915-5287 2187-5626 2187-5626 |
| DOI | 10.1589/jpts.28.3213 |
Cover
| Abstract | [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus femoris, biceps femoris long head and gastrocnemius lateral head muscles during ramp cycling exercise in elderly males. [Subjects and Methods] Eleven community dwelling elderly males participated in this study. Subjects performed exercise testing with an expiratory gas analyzer and surface electromyography to evaluate the tested muscle activities during ramp exercise. [Results] The electromyographic threshold for rectus femoris was not valid because the slope after electromyographic threshold was not significant as compared to that before electromyographic threshold. The slope of the regression line for vastus lateralis was significantly decreased after electromyographic threshold while biceps femoris and gastrocnemius were increased. The electromyographic threshold appearance times for vastus lateralis and gastrocnemius were significantly earlier than ventilatory threshold point. There were no difference in electromyographic threshold appearance times among three muscles. [Conclusion] These results suggest that the increase in the slope of the regression line after electromyographic threshold for vastus lateralis was decreased, possibly indicating to postpone muscular fatigue resulting from the activation of biceps femoris and gastrocnemius as biarticular antagonists. This recruitment pattern might be an elderly-specific strategy. |
|---|---|
| AbstractList | [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus femoris, biceps femoris long head and gastrocnemius lateral head muscles during ramp cycling exercise in elderly males. [Subjects and Methods] Eleven community dwelling elderly males participated in this study. Subjects performed exercise testing with an expiratory gas analyzer and surface electromyography to evaluate the tested muscle activities during ramp exercise. [Results] The electromyographic threshold for rectus femoris was not valid because the slope after electromyographic threshold was not significant as compared to that before electromyographic threshold. The slope of the regression line for vastus lateralis was significantly decreased after electromyographic threshold while biceps femoris and gastrocnemius were increased. The electromyographic threshold appearance times for vastus lateralis and gastrocnemius were significantly earlier than ventilatory threshold point. There were no difference in electromyographic threshold appearance times among three muscles. [Conclusion] These results suggest that the increase in the slope of the regression line after electromyographic threshold for vastus lateralis was decreased, possibly indicating to postpone muscular fatigue resulting from the activation of biceps femoris and gastrocnemius as biarticular antagonists. This recruitment pattern might be an elderly-specific strategy. [Abstract.] [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus femoris, biceps femoris long head and gastrocnemius lateral head muscles during ramp cycling exercise in elderly males. [Subjects and Methods] Eleven community dwelling elderly males participated in this study. Subjects performed exercise testing with an expiratory gas analyzer and surface electromyography to evaluate the tested muscle activities during ramp exercise. [Results] The electromyographic threshold for rectus femoris was not valid because the slope after electromyographic threshold was not significant as compared to that before electromyographic threshold. The slope of the regression line for vastus lateralis was significantly decreased after electromyographic threshold while biceps femoris and gastrocnemius were increased. The electromyographic threshold appearance times for vastus lateralis and gastrocnemius were significantly earlier than ventilatory threshold point. There were no difference in electromyographic threshold appearance times among three muscles. [Conclusion] These results suggest that the increase in the slope of the regression line after electromyographic threshold for vastus lateralis was decreased, possibly indicating to postpone muscular fatigue resulting from the activation of biceps femoris and gastrocnemius as biarticular antagonists. This recruitment pattern might be an elderly-specific strategy. Purpose: To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus femoris, biceps femoris long head and gastrocnemius lateral head muscles during ramp cycling exercise in elderly males. Subjects and Methods: Eleven community dwelling elderly males participated in this study. Subjects performed exercise testing with an expiratory gas analyzer and surface electromyography to evaluate the tested muscle activities during ramp exercise. Results: The electromyographic threshold for rectus femoris was not valid because the slope after electromyographic threshold was not significant as compared to that before electromyographic threshold. The slope of the regression line for vastus lateralis was significantly decreased after electromyographic threshold while biceps femoris and gastrocnemius were increased. The electromyographic threshold appearance times for vastus lateralis and gastrocnemius were significantly earlier than ventilatory threshold point. There were no difference in electromyographic threshold appearance times among three muscles. Conclusion: These results suggest that the increase in the slope of the regression line after electromyographic threshold for vastus lateralis was decreased, possibly indicating to postpone muscular fatigue resulting from the activation of biceps femoris and gastrocnemius as biarticular antagonists. This recruitment pattern might be an elderly-specific strategy. [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus femoris, biceps femoris long head and gastrocnemius lateral head muscles during ramp cycling exercise in elderly males. [Subjects and Methods] Eleven community dwelling elderly males participated in this study. Subjects performed exercise testing with an expiratory gas analyzer and surface electromyography to evaluate the tested muscle activities during ramp exercise. [Results] The electromyographic threshold for rectus femoris was not valid because the slope after electromyographic threshold was not significant as compared to that before electromyographic threshold. The slope of the regression line for vastus lateralis was significantly decreased after electromyographic threshold while biceps femoris and gastrocnemius were increased. The electromyographic threshold appearance times for vastus lateralis and gastrocnemius were significantly earlier than ventilatory threshold point. There were no difference in electromyographic threshold appearance times among three muscles. [Conclusion] These results suggest that the increase in the slope of the regression line after electromyographic threshold for vastus lateralis was decreased, possibly indicating to postpone muscular fatigue resulting from the activation of biceps femoris and gastrocnemius as biarticular antagonists. This recruitment pattern might be an elderly-specific strategy. |
| Author | Higuchi, Hiroyuki Sasaki, Kentaro Kimura, Tsuyoshi Kojima, Satoshi |
| Author_xml | – sequence: 1 fullname: Higuchi, Hiroyuki organization: Graduate School of Health Sciences (Division of Distance Education), Kyushu University of Health and Welfare, Japan – sequence: 1 fullname: Sasaki, Kentaro organization: Graduate School of Health Sciences (Division of Distance Education), Kyushu University of Health and Welfare, Japan – sequence: 1 fullname: Kimura, Tsuyoshi organization: Department of Social Welfare, Faculty of Social Welfare, Kinjo University, Japan – sequence: 1 fullname: Kojima, Satoshi organization: Department of Physical Therapy, Kinjo University: 1200 Kasama-machi, Hakusan-city, Ishikawa 924-8511, Japan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27942152$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkk9v1DAQxSNURLeFG2fkIwey2E6cOBckVEGpVIlLOVuOM9n1yrGD7ex2vwUfGacpyx8JwcU--PeeZ97MRXZmnYUse0nwmjDevN2NMawpXxeUFE-yFSW8zllFq7NshRvCckZ5fZ5dhLDDmNa45M-yc1o3JSWMrrJvd1tAEYbReWmQByOjdjZs9Yhcj-LWQ9g60wXUQjwAWDRMQRlAUkW91_GIpO3QHmzUixJ1k9d2g1qtjjPn5TAiuAevdACkLVJuGCY7K7sDGDOzYDrw5ogGaSA8z5720gR48XhfZl8-fri7-pTffr6-uXp_m6uKFUXO2pZx2hOcesQlppyXJelA9RIwVi3ualVI6HEvecE5bhhULZO8Jz1IKnFbXGb54jvZUR4P0hgxej1IfxQEizlZMScrKBdzsol_t_Dj1A7QqdRySuykcVKL31-s3oqN2wtGSswLmgxePxp493WCEMWgg0oRSAtuCoJw1pS8KkryPyitEtnMrq9-LetUz48JJ-DNAijvQvDQ_6tN-geudHyYbGpKm7-JrhdRqkAraZxNcwWxc5O3aYZCSb5bBJhUIq0hJ0TgsnpQz0dD66qo2ex0szjtQpQbONUqfdRpnU7fJn06f3pWrDwxaiu9AFt8BzFz_zc |
| CitedBy_id | crossref_primary_10_1016_j_ancard_2017_09_006 crossref_primary_10_1109_THMS_2023_3347404 crossref_primary_10_3389_fphys_2022_821584 |
| Cites_doi | 10.1152/japplphysiol.00606.2004 10.1177/2047487312460484 10.1249/MSS.0b013e3182100261 10.1136/bjsm.33.3.178 10.1113/expphysiol.2012.067314 10.3389/fphys.2014.00142 10.1152/ajpheart.00790.2002 10.1016/0306-4522(92)90019-X 10.2466/06.10.15.PMS.112.1.310-318 10.2170/jjphysiol.31.585 10.1249/00005768-199208000-00013 10.1016/0002-9149(64)90012-8 10.2165/00007256-198805050-00002 10.1152/japplphysiol.01216.2010 10.1001/jama.298.21.2507 10.1007/s00421-003-0949-5 10.1111/j.1469-7793.2000.00211.x 10.1111/j.1748-1716.1985.tb07663.x 10.1139/Y08-020 10.1016/j.jelekin.2007.10.010 10.1253/circj.CJ-13-0847 10.7600/jspfsm1949.49.183 10.1016/j.jjcc.2012.09.010 10.1007/s00421-007-0568-7 10.1016/j.jelekin.2010.02.004 10.1093/ajcn/81.5.953 10.1007/s00421-007-0509-5 10.1007/s11357-012-9442-6 |
| ContentType | Journal Article |
| Copyright | 2016 by the Society of Physical Therapy Science. Published by IPEC Inc. 2016©by the Society of Physical Therapy Science. Published by IPEC Inc. 2016 |
| Copyright_xml | – notice: 2016 by the Society of Physical Therapy Science. Published by IPEC Inc. – notice: 2016©by the Society of Physical Therapy Science. Published by IPEC Inc. 2016 |
| CorporateAuthor | Faculty of Social Welfare Department of Social Welfare Graduate School of Health Sciences (Division of Distance Education Kinjo University Department of Physical Therapy Kyushu University of Health and Welfare |
| CorporateAuthor_xml | – name: Faculty of Social Welfare – name: Graduate School of Health Sciences (Division of Distance Education – name: Department of Physical Therapy – name: Kinjo University – name: Kyushu University of Health and Welfare – name: Department of Social Welfare |
| DBID | AAYXX CITATION NPM 7X8 7TS 5PM ADTOC UNPAY |
| DOI | 10.1589/jpts.28.3213 |
| DatabaseName | CrossRef PubMed MEDLINE - Academic Physical Education Index PubMed Central (Full Participant titles) Unpaywall for CDI: Periodical Content Unpaywall |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic Physical Education Index |
| DatabaseTitleList | MEDLINE - Academic PubMed Physical Education Index |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: UNPAY name: Unpaywall url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/ sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Physical Therapy |
| EISSN | 2187-5626 |
| EndPage | 3219 |
| ExternalDocumentID | 10.1589/jpts.28.3213 PMC5140832 27942152 10_1589_jpts_28_3213 ca8jjpts_2016_002811_046_3213_32192763753 article_jpts_28_11_28_jpts_2016_654_article_char_en |
| Genre | Journal Article |
| GroupedDBID | .55 07C 29L 2WC 53G 5GY AAEJM AAWTL ACGFO ADBBV ADRAZ AENEX AIAGR AJJEV ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BKOMP BMSDO CS3 DIK DU5 E3Z EBS EJD FRP GX1 HYE JMI JSF JSH KQ8 M48 MOJWN OK1 OVT P2P PGMZT RJT RNS RPM RZJ TKC TR2 W2D X7M XSB AAYXX CITATION ACRZS NPM 7X8 7TS 5PM ADTOC UNPAY |
| ID | FETCH-LOGICAL-c6533-5bb582f10091040288441decfae00cb0d7c3aef0fa8388095e6b5a8f1fea2a0b3 |
| IEDL.DBID | M48 |
| ISSN | 0915-5287 2187-5626 |
| IngestDate | Wed Oct 29 12:20:42 EDT 2025 Thu Aug 21 18:24:54 EDT 2025 Fri Jul 11 08:25:58 EDT 2025 Thu Jul 10 18:27:59 EDT 2025 Sat Sep 28 07:58:30 EDT 2024 Tue Jul 01 04:12:10 EDT 2025 Thu Apr 24 23:07:08 EDT 2025 Thu Jul 10 16:12:56 EDT 2025 Wed Sep 03 06:30:05 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 11 |
| Keywords | Electromyographic threshold Community dwelling elderly males Ventilatory threshold |
| Language | English |
| License | https://creativecommons.org/licenses/by-nc-nd/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. cc-by-nc-nd |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c6533-5bb582f10091040288441decfae00cb0d7c3aef0fa8388095e6b5a8f1fea2a0b3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.1589/jpts.28.3213 |
| PMID | 27942152 |
| PQID | 1852663492 |
| PQPubID | 23479 |
| PageCount | 7 |
| ParticipantIDs | unpaywall_primary_10_1589_jpts_28_3213 pubmedcentral_primary_oai_pubmedcentral_nih_gov_5140832 proquest_miscellaneous_1859486341 proquest_miscellaneous_1852663492 pubmed_primary_27942152 crossref_primary_10_1589_jpts_28_3213 crossref_citationtrail_10_1589_jpts_28_3213 medicalonline_journals_ca8jjpts_2016_002811_046_3213_32192763753 jstage_primary_article_jpts_28_11_28_jpts_2016_654_article_char_en |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 20160000 |
| PublicationDateYYYYMMDD | 2016-01-01 |
| PublicationDate_xml | – year: 2016 text: 20160000 |
| PublicationDecade | 2010 |
| PublicationPlace | Japan |
| PublicationPlace_xml | – name: Japan |
| PublicationTitle | Journal of Physical Therapy Science |
| PublicationTitleAlternate | Journal of Physical Therapy Science |
| PublicationYear | 2016 |
| Publisher | The Society of Physical Therapy Science |
| Publisher_xml | – name: The Society of Physical Therapy Science |
| References | 19) Candotti CT, Loss JF, Melo MO, et al.: Comparing the lactate and EMG thresholds of recreational cyclists during incremental pedaling exercise. Can J Physiol Pharmacol, 2008, 86: 272–278. 9) Nagata A, Muro M, Moritani T, et al.: Anaerobic threshold determination by blood lactate and myoelectric signals. Jpn J Physiol, 1981, 31: 585–597. 30) Farina D, Macaluso A, Ferguson RA, et al.: Effect of power, pedal rate, and force on average muscle fiber conduction velocity during cycling. J Appl Physiol 1985, 2004, 97: 2035–2041. 15) Lucía A, Sánchez O, Carvajal A, et al.: Analysis of the aerobic-anaerobic transition in elite cyclists during incremental exercise with the use of electromyography. Br J Sports Med, 1999, 33: 178–185. 20) Osawa T, Kime R, Hamaoka T, et al.: Attenuation of muscle deoxygenation precedes EMG threshold in normoxia and hypoxia. Med Sci Sports Exerc, 2011, 43: 1406–1413. 31) Nair KS: Aging muscle. Am J Clin Nutr, 2005, 81: 953–963. 10) Moritani T, deVries HA: Reexamination of the relationship between the surface integrated electromyogram (IEMG) and force of isometric contraction. Am J Phys Med, 1978, 57: 263–277. 28) Ericson M: On the biomechanics of cycling. A study of joint and muscle load during exercise on the bicycle ergometer. Scand J Rehabil Med Suppl, 1986, 16: 1–43. 33) Layec G, Haseler LJ, Richardson RS: Reduced muscle oxidative capacity is independent of O2 availability in elderly people. Age (Dordr), 2013, 35: 1183–1192. 25) Hug F, Dorel S: Electromyographic analysis of pedaling: a review. J Electromyogr Kinesiol, 2009, 19: 182–198. 34) Poole JG, Lawrenson L, Kim J, et al.: Vascular and metabolic response to cycle exercise in sedentary humans: effect of age. Am J Physiol Heart Circ Physiol, 2003, 284: H1251–H1259. 17) Jürimäe J, von Duvillard SP, Mäestu J, et al.: Aerobic-anaerobic transition intensity measured via EMG signals in athletes with different physical activity patterns. Eur J Appl Physiol, 2007, 101: 341–346. 27) Chin LM, Kowalchuk JM, Barstow TJ, et al.: The relationship between muscle deoxygenation and activation in different muscles of the quadriceps during cycle ramp exercise. J Appl Physiol 1985, 2011, 111: 1259–1265. 7) Miura K, Nagai M, Ohkubo T: Epidemiology of hypertension in Japan: where are we now? Circ J, 2013, 77: 2226–2231. 16) Hug F, Laplaud D, Savin B, et al.: Occurrence of electromyographic and ventilatory thresholds in professional road cyclists. Eur J Appl Physiol, 2003, 90: 643–646. 29) Lenti M, De Vito G, Sbriccoli P, et al.: Muscle fibre conduction velocity and cardiorespiratory response during incremental cycling exercise in young and older individuals with different training status. J Electromyogr Kinesiol, 2010, 20: 566–571. 32) Conley KE, Jubrias SA, Cress ME, et al.: Exercise efficiency is reduced by mitochondrial uncoupling in the elderly. Exp Physiol, 2013, 98: 768–777. 6) Goss FL, Robertson RJ, Haile L, et al.: Use of ratings of perceived exertion to anticipate treadmill test termination in patients taking beta-blockers. Percept Mot Skills, 2011, 112: 310–318. 14) Glass SC, Knowlton RG, Sanjabi PB, et al.: Identifying the integrated electromyographic threshold using different muscles during incremental cycling exercise. J Sports Med Phys Fitness, 1998, 38: 47–52. 22) Lieber RL: Skeletal muscle structure, function, and plasticity, 3rd ed. Baltimore: Lippincott Williams & Wilkins, a Wolters Kluwer business, 2009, pp 207–212. 36) Higuchi H, Katsumura T, Hamaoka T, et al.: Pattern of deoxygenation in vastus lateralis and rectus femoris muscles during a ramp-road cycling. JPFSM, 2000, 49: 183–192 (in Japanese). 24) Itoh H, Ajisaka R, Koike A, et al. Committee on Exercise Prescription for Patients (CEPP) Members: Heart rate and blood pressure response to ramp exercise and exercise capacity in relation to age, gender, and mode of exercise in a healthy population. J Cardiol, 2013, 61: 71–78. 1) Sawada S, Muto T: [Prospective study on the relationship between physical fitness and all-cause mortality in Japanese men]. Nippon Koshu Eisei Zasshi, 1999, 46: 113–121 (in Japanese). 3) Wasserman K, McIlroy MB: Detecting the threshold of anaerobic metabolism in cardiac patients during exercise. Am J Cardiol, 1964, 14: 844–852. 26) Conley KE, Esselman PC, Jubrias SA, et al.: Ageing, muscle properties and maximal O(2) uptake rate in humans. J Physiol, 2000, 526: 211–217. 18) Rupp T, Perrey S: Prefrontal cortex oxygenation and neuromuscular responses to exhaustive exercise. Eur J Appl Physiol, 2008, 102: 153–163. 21) Racinais S, Buchheit M, Girard O: Breakpoints in ventilation, cerebral and muscle oxygenation, and muscle activity during an incremental cycling exercise. Front Physiol, 2014, 5: 142. 13) Seburn KL, Sanderson DJ, Belcastro AN, et al.: Effect of manipulation of plasma lactate on integrated EMG during cycling. Med Sci Sports Exerc, 1992, 24: 911–916. 8) The Japanese Society of Hypertension: Guidelines for the management of hypertension 2014. Tokyo: The Japanese Society of hypertension, 2014, pp 7–11. 12) Viitasalo JT, Luhtanen P, Rahkila P, et al.: Electromyographic activity related to aerobic and anaerobic threshold in ergometer bicycling. Acta Physiol Scand, 1985, 124: 287–293. 35) van Ingen Schenau GJ, Boots PJ, de Groot G, et al.: The constrained control of force and position in multi-joint movements. Neuroscience, 1992, 46: 197–207. 4) Mezzani A, Hamm LF, Jones AM, et al. European Association for Cardiovascular Prevention and Rehabilitation American Association of Cardiovascular and Pulmonary Rehabilitation Canadian Association of Cardiac Rehabilitation: Aerobic exercise intensity assessment and prescription in cardiac rehabilitation: a joint position statement of the European Association for Cardiovascular Prevention and Rehabilitation, the American Association of Cardiovascular and Pulmonary Rehabilitation and the Canadian Association of Cardiac Rehabilitation. Eur J Prev Cardiol, 2013, 20: 442–467. 5) Karvonen J, Vuorimaa T: Heart rate and exercise intensity during sports activities. Practical application. Sports Med, 1988, 5: 303–311. 2) Sui X, LaMonte MJ, Laditka JN, et al.: Cardiorespiratory fitness and adiposity as mortality predictors in older adults. JAMA, 2007, 298: 2507–2516. 11) Miyashita M, Kanehisa H, Nemoto I: EMG related to anaerobic threshold. J Sports Med Phys Fitness, 1981, 21: 209–217. 23) Ministry of Health: Labour and Welfare. Healthy Japan 21 (physical activity·exercise). http://www1.mhlw.go.jp/topics/kenko21_11/b2.html (Accessed Jun. 6, 2015 22 23 24 25 26 27 28 29 30 31 10 32 11 33 12 34 13 35 14 36 15 16 17 18 19 1 2 3 4 5 6 7 8 9 20 21 21266933 - Med Sci Sports Exerc. 2011 Aug;43(8):1406-13 18093842 - J Electromyogr Kinesiol. 2009 Apr;19(2):182-98 10878113 - J Physiol. 2000 Jul 1;526 Pt 1:211-7 15883415 - Am J Clin Nutr. 2005 May;81(5):953-63 7321550 - J Sports Med Phys Fitness. 1981 Sep;21(3):209-17 14232808 - Am J Cardiol. 1964 Dec;14:844-52 1406177 - Med Sci Sports Exerc. 1992 Aug;24(8):911-6 15286050 - J Appl Physiol (1985). 2004 Dec;97(6):2035-41 10331296 - Nihon Koshu Eisei Zasshi. 1999 Feb;46(2):113-21 21466104 - Percept Mot Skills. 2011 Feb;112(1):310-8 17882449 - Eur J Appl Physiol. 2008 Jan;102(2):153-63 23085769 - Exp Physiol. 2013 Mar;98(3):768-77 20202863 - J Electromyogr Kinesiol. 2010 Aug;20(4):566-71 18432288 - Can J Physiol Pharmacol. 2008 May;86(5):272-8 7328909 - Jpn J Physiol. 1981;31(4):585-97 21799133 - J Appl Physiol (1985). 2011 Nov;111(5):1259-65 23902998 - Circ J. 2013;77(9):2226-31 742657 - Am J Phys Med. 1978 Dec;57(6):263-77 14508692 - Eur J Appl Physiol. 2003 Nov;90(5-6):643-6 23104970 - Eur J Prev Cardiol. 2013 Jun;20(3):442-67 24782786 - Front Physiol. 2014 Apr 11;5:142 18056904 - JAMA. 2007 Dec 5;298(21):2507-16 17624542 - Eur J Appl Physiol. 2007 Oct;101(3):341-6 1594103 - Neuroscience. 1992;46(1):197-207 3387734 - Sports Med. 1988 May;5(5):303-11 10378070 - Br J Sports Med. 1999 Jun;33(3):178-85 22760857 - Age (Dordr). 2013 Aug;35(4):1183-92 9638032 - J Sports Med Phys Fitness. 1998 Mar;38(1):47-52 23182944 - J Cardiol. 2013 Jan;61(1):71-8 12595287 - Am J Physiol Heart Circ Physiol. 2003 Apr;284(4):H1251-9 3468609 - Scand J Rehabil Med Suppl. 1986;16:1-43 4013794 - Acta Physiol Scand. 1985 Jun;124(2):287-93 |
| References_xml | – reference: 35) van Ingen Schenau GJ, Boots PJ, de Groot G, et al.: The constrained control of force and position in multi-joint movements. Neuroscience, 1992, 46: 197–207. – reference: 34) Poole JG, Lawrenson L, Kim J, et al.: Vascular and metabolic response to cycle exercise in sedentary humans: effect of age. Am J Physiol Heart Circ Physiol, 2003, 284: H1251–H1259. – reference: 33) Layec G, Haseler LJ, Richardson RS: Reduced muscle oxidative capacity is independent of O2 availability in elderly people. Age (Dordr), 2013, 35: 1183–1192. – reference: 22) Lieber RL: Skeletal muscle structure, function, and plasticity, 3rd ed. Baltimore: Lippincott Williams & Wilkins, a Wolters Kluwer business, 2009, pp 207–212. – reference: 12) Viitasalo JT, Luhtanen P, Rahkila P, et al.: Electromyographic activity related to aerobic and anaerobic threshold in ergometer bicycling. Acta Physiol Scand, 1985, 124: 287–293. – reference: 8) The Japanese Society of Hypertension: Guidelines for the management of hypertension 2014. Tokyo: The Japanese Society of hypertension, 2014, pp 7–11. – reference: 11) Miyashita M, Kanehisa H, Nemoto I: EMG related to anaerobic threshold. J Sports Med Phys Fitness, 1981, 21: 209–217. – reference: 25) Hug F, Dorel S: Electromyographic analysis of pedaling: a review. J Electromyogr Kinesiol, 2009, 19: 182–198. – reference: 7) Miura K, Nagai M, Ohkubo T: Epidemiology of hypertension in Japan: where are we now? Circ J, 2013, 77: 2226–2231. – reference: 16) Hug F, Laplaud D, Savin B, et al.: Occurrence of electromyographic and ventilatory thresholds in professional road cyclists. Eur J Appl Physiol, 2003, 90: 643–646. – reference: 15) Lucía A, Sánchez O, Carvajal A, et al.: Analysis of the aerobic-anaerobic transition in elite cyclists during incremental exercise with the use of electromyography. Br J Sports Med, 1999, 33: 178–185. – reference: 24) Itoh H, Ajisaka R, Koike A, et al. Committee on Exercise Prescription for Patients (CEPP) Members: Heart rate and blood pressure response to ramp exercise and exercise capacity in relation to age, gender, and mode of exercise in a healthy population. J Cardiol, 2013, 61: 71–78. – reference: 2) Sui X, LaMonte MJ, Laditka JN, et al.: Cardiorespiratory fitness and adiposity as mortality predictors in older adults. JAMA, 2007, 298: 2507–2516. – reference: 21) Racinais S, Buchheit M, Girard O: Breakpoints in ventilation, cerebral and muscle oxygenation, and muscle activity during an incremental cycling exercise. Front Physiol, 2014, 5: 142. – reference: 32) Conley KE, Jubrias SA, Cress ME, et al.: Exercise efficiency is reduced by mitochondrial uncoupling in the elderly. Exp Physiol, 2013, 98: 768–777. – reference: 13) Seburn KL, Sanderson DJ, Belcastro AN, et al.: Effect of manipulation of plasma lactate on integrated EMG during cycling. Med Sci Sports Exerc, 1992, 24: 911–916. – reference: 29) Lenti M, De Vito G, Sbriccoli P, et al.: Muscle fibre conduction velocity and cardiorespiratory response during incremental cycling exercise in young and older individuals with different training status. J Electromyogr Kinesiol, 2010, 20: 566–571. – reference: 31) Nair KS: Aging muscle. Am J Clin Nutr, 2005, 81: 953–963. – reference: 14) Glass SC, Knowlton RG, Sanjabi PB, et al.: Identifying the integrated electromyographic threshold using different muscles during incremental cycling exercise. J Sports Med Phys Fitness, 1998, 38: 47–52. – reference: 26) Conley KE, Esselman PC, Jubrias SA, et al.: Ageing, muscle properties and maximal O(2) uptake rate in humans. J Physiol, 2000, 526: 211–217. – reference: 27) Chin LM, Kowalchuk JM, Barstow TJ, et al.: The relationship between muscle deoxygenation and activation in different muscles of the quadriceps during cycle ramp exercise. J Appl Physiol 1985, 2011, 111: 1259–1265. – reference: 17) Jürimäe J, von Duvillard SP, Mäestu J, et al.: Aerobic-anaerobic transition intensity measured via EMG signals in athletes with different physical activity patterns. Eur J Appl Physiol, 2007, 101: 341–346. – reference: 20) Osawa T, Kime R, Hamaoka T, et al.: Attenuation of muscle deoxygenation precedes EMG threshold in normoxia and hypoxia. Med Sci Sports Exerc, 2011, 43: 1406–1413. – reference: 18) Rupp T, Perrey S: Prefrontal cortex oxygenation and neuromuscular responses to exhaustive exercise. Eur J Appl Physiol, 2008, 102: 153–163. – reference: 4) Mezzani A, Hamm LF, Jones AM, et al. European Association for Cardiovascular Prevention and Rehabilitation American Association of Cardiovascular and Pulmonary Rehabilitation Canadian Association of Cardiac Rehabilitation: Aerobic exercise intensity assessment and prescription in cardiac rehabilitation: a joint position statement of the European Association for Cardiovascular Prevention and Rehabilitation, the American Association of Cardiovascular and Pulmonary Rehabilitation and the Canadian Association of Cardiac Rehabilitation. Eur J Prev Cardiol, 2013, 20: 442–467. – reference: 9) Nagata A, Muro M, Moritani T, et al.: Anaerobic threshold determination by blood lactate and myoelectric signals. Jpn J Physiol, 1981, 31: 585–597. – reference: 28) Ericson M: On the biomechanics of cycling. A study of joint and muscle load during exercise on the bicycle ergometer. Scand J Rehabil Med Suppl, 1986, 16: 1–43. – reference: 5) Karvonen J, Vuorimaa T: Heart rate and exercise intensity during sports activities. Practical application. Sports Med, 1988, 5: 303–311. – reference: 6) Goss FL, Robertson RJ, Haile L, et al.: Use of ratings of perceived exertion to anticipate treadmill test termination in patients taking beta-blockers. Percept Mot Skills, 2011, 112: 310–318. – reference: 23) Ministry of Health: Labour and Welfare. Healthy Japan 21 (physical activity·exercise). http://www1.mhlw.go.jp/topics/kenko21_11/b2.html (Accessed Jun. 6, 2015) – reference: 1) Sawada S, Muto T: [Prospective study on the relationship between physical fitness and all-cause mortality in Japanese men]. Nippon Koshu Eisei Zasshi, 1999, 46: 113–121 (in Japanese). – reference: 30) Farina D, Macaluso A, Ferguson RA, et al.: Effect of power, pedal rate, and force on average muscle fiber conduction velocity during cycling. J Appl Physiol 1985, 2004, 97: 2035–2041. – reference: 3) Wasserman K, McIlroy MB: Detecting the threshold of anaerobic metabolism in cardiac patients during exercise. Am J Cardiol, 1964, 14: 844–852. – reference: 36) Higuchi H, Katsumura T, Hamaoka T, et al.: Pattern of deoxygenation in vastus lateralis and rectus femoris muscles during a ramp-road cycling. JPFSM, 2000, 49: 183–192 (in Japanese). – reference: 19) Candotti CT, Loss JF, Melo MO, et al.: Comparing the lactate and EMG thresholds of recreational cyclists during incremental pedaling exercise. Can J Physiol Pharmacol, 2008, 86: 272–278. – reference: 10) Moritani T, deVries HA: Reexamination of the relationship between the surface integrated electromyogram (IEMG) and force of isometric contraction. Am J Phys Med, 1978, 57: 263–277. – ident: 30 doi: 10.1152/japplphysiol.00606.2004 – ident: 4 doi: 10.1177/2047487312460484 – ident: 20 doi: 10.1249/MSS.0b013e3182100261 – ident: 10 – ident: 15 doi: 10.1136/bjsm.33.3.178 – ident: 32 doi: 10.1113/expphysiol.2012.067314 – ident: 14 – ident: 21 doi: 10.3389/fphys.2014.00142 – ident: 28 – ident: 34 doi: 10.1152/ajpheart.00790.2002 – ident: 35 doi: 10.1016/0306-4522(92)90019-X – ident: 6 doi: 10.2466/06.10.15.PMS.112.1.310-318 – ident: 9 doi: 10.2170/jjphysiol.31.585 – ident: 13 doi: 10.1249/00005768-199208000-00013 – ident: 3 doi: 10.1016/0002-9149(64)90012-8 – ident: 22 – ident: 5 doi: 10.2165/00007256-198805050-00002 – ident: 27 doi: 10.1152/japplphysiol.01216.2010 – ident: 2 doi: 10.1001/jama.298.21.2507 – ident: 1 – ident: 11 – ident: 16 doi: 10.1007/s00421-003-0949-5 – ident: 26 doi: 10.1111/j.1469-7793.2000.00211.x – ident: 12 doi: 10.1111/j.1748-1716.1985.tb07663.x – ident: 19 doi: 10.1139/Y08-020 – ident: 25 doi: 10.1016/j.jelekin.2007.10.010 – ident: 7 doi: 10.1253/circj.CJ-13-0847 – ident: 36 doi: 10.7600/jspfsm1949.49.183 – ident: 24 doi: 10.1016/j.jjcc.2012.09.010 – ident: 18 doi: 10.1007/s00421-007-0568-7 – ident: 29 doi: 10.1016/j.jelekin.2010.02.004 – ident: 31 doi: 10.1093/ajcn/81.5.953 – ident: 17 doi: 10.1007/s00421-007-0509-5 – ident: 8 – ident: 23 – ident: 33 doi: 10.1007/s11357-012-9442-6 – reference: 22760857 - Age (Dordr). 2013 Aug;35(4):1183-92 – reference: 7321550 - J Sports Med Phys Fitness. 1981 Sep;21(3):209-17 – reference: 21266933 - Med Sci Sports Exerc. 2011 Aug;43(8):1406-13 – reference: 23182944 - J Cardiol. 2013 Jan;61(1):71-8 – reference: 1406177 - Med Sci Sports Exerc. 1992 Aug;24(8):911-6 – reference: 3387734 - Sports Med. 1988 May;5(5):303-11 – reference: 3468609 - Scand J Rehabil Med Suppl. 1986;16:1-43 – reference: 18093842 - J Electromyogr Kinesiol. 2009 Apr;19(2):182-98 – reference: 9638032 - J Sports Med Phys Fitness. 1998 Mar;38(1):47-52 – reference: 23085769 - Exp Physiol. 2013 Mar;98(3):768-77 – reference: 23104970 - Eur J Prev Cardiol. 2013 Jun;20(3):442-67 – reference: 4013794 - Acta Physiol Scand. 1985 Jun;124(2):287-93 – reference: 10878113 - J Physiol. 2000 Jul 1;526 Pt 1:211-7 – reference: 20202863 - J Electromyogr Kinesiol. 2010 Aug;20(4):566-71 – reference: 21466104 - Percept Mot Skills. 2011 Feb;112(1):310-8 – reference: 24782786 - Front Physiol. 2014 Apr 11;5:142 – reference: 15883415 - Am J Clin Nutr. 2005 May;81(5):953-63 – reference: 21799133 - J Appl Physiol (1985). 2011 Nov;111(5):1259-65 – reference: 742657 - Am J Phys Med. 1978 Dec;57(6):263-77 – reference: 17882449 - Eur J Appl Physiol. 2008 Jan;102(2):153-63 – reference: 1594103 - Neuroscience. 1992;46(1):197-207 – reference: 7328909 - Jpn J Physiol. 1981;31(4):585-97 – reference: 12595287 - Am J Physiol Heart Circ Physiol. 2003 Apr;284(4):H1251-9 – reference: 14508692 - Eur J Appl Physiol. 2003 Nov;90(5-6):643-6 – reference: 18432288 - Can J Physiol Pharmacol. 2008 May;86(5):272-8 – reference: 14232808 - Am J Cardiol. 1964 Dec;14:844-52 – reference: 10331296 - Nihon Koshu Eisei Zasshi. 1999 Feb;46(2):113-21 – reference: 10378070 - Br J Sports Med. 1999 Jun;33(3):178-85 – reference: 15286050 - J Appl Physiol (1985). 2004 Dec;97(6):2035-41 – reference: 17624542 - Eur J Appl Physiol. 2007 Oct;101(3):341-6 – reference: 23902998 - Circ J. 2013;77(9):2226-31 – reference: 18056904 - JAMA. 2007 Dec 5;298(21):2507-16 |
| SSID | ssj0027048 |
| Score | 2.0134957 |
| Snippet | [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus... [Abstract.] [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus... Purpose: To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus... [Purpose] To compare the appearance time of the ventilatory threshold point and the electromyographic threshold in the activity of the vastus lateralis, rectus... |
| SourceID | unpaywall pubmedcentral proquest pubmed crossref medicalonline jstage |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 3213 |
| SubjectTerms | Community dwelling elderly males Electromyographic threshold Original Ventilatory threshold |
| SummonAdditionalLinks | – databaseName: Unpaywall dbid: UNPAY link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3rb9MwELdGhwQIMd6El4wEfEFJ83LifGOgTRMS0z6s0vhk2Ym9tbRp1LRC5a_gT-YudgPlMSHxJW3Vs9P6zne_i-9ByEvADEanPPM5y7Wfqoj7yujKT2NQhChFpot2_3icHY3SD2fsbIccbHJhMKxyArjoXONLcD4PJs3QLeJw0izbYcyHUQRXgZ-AyVHmZywdiqYyV8huxgCSD8ju6Phk_1NXZy9i4Gx1jfLAmuU-2PvMBcAzXnRTBjEPkjhKtkzTVfsrbpCbM3tiYitX_AmI_h5PeW1VN3L9RU6nPxmrwz0bVNJ2NQ4xRuVzsFqqoPz6SwXI_16H2-SWg7N03w65Q3Z0fZfsnTjm01Nbs-Ae-QbvqCuDNaWLTQTexbihc0OXIFAtnoO11MWN0dmqhQkppl1gdwsq64p2oZl2JLXplVSNyzXSLeSsoZv2UXRc09ImvsDICh9PIq3GhuTTNZ2BTWzvk9Hhwen7I981g_DLDCCpz5RiPDZRiAAHnF7OAchVujRSh2GpwiovE6lNaCTH-jYF05likpvIaBnLUCUPyKCe1_oRoamRYSFjxRKVp0orlSaalSzPZSElOFgeebORA1G6SunYsGMq0GMCqemWXMDSo9R45FVP3dgKIX-he2cZ2lM5dvZU4Io5dgpkpwB29jSYgweKzCNvt8RROI3TilLyyY-h6ErDdGGadffGSxGDKQHn1CMvNhIsQJXg-ZCs9XzVCsyjBwCaFvGlNAVsbcA-Hnlopb7_PzHodmyT7JF8az_0BFjKfPubenzRlTQH2A6-AIx83e-cSxfz8b8SPiHXu63RPTR7SgbLxUo_Axi5VM-dkvgODxp3Fw priority: 102 providerName: Unpaywall |
| Title | The temporal relationship of thresholds between muscle activity and ventilation during bicycle ramp exercise in community dwelling elderly males |
| URI | https://www.jstage.jst.go.jp/article/jpts/28/11/28_jpts-2016-654/_article/-char/en http://mol.medicalonline.jp/en/journal/download?GoodsID=ca8jjpts/2016/002811/046&name=3213-3219e https://www.ncbi.nlm.nih.gov/pubmed/27942152 https://www.proquest.com/docview/1852663492 https://www.proquest.com/docview/1859486341 https://pubmed.ncbi.nlm.nih.gov/PMC5140832 https://www.jstage.jst.go.jp/article/jpts/28/11/28_jpts-2016-654/_pdf |
| UnpaywallVersion | publishedVersion |
| Volume | 28 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | Journal of Physical Therapy Science, 2016, Vol.28(11), pp.3213-3219 |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2187-5626 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0027048 issn: 0915-5287 databaseCode: KQ8 dateStart: 20130101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2187-5626 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0027048 issn: 0915-5287 databaseCode: KQ8 dateStart: 19950101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 2187-5626 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0027048 issn: 0915-5287 databaseCode: DIK dateStart: 19950101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVFQY databaseName: GFMER Free Medical Journals customDbUrl: eissn: 2187-5626 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0027048 issn: 0915-5287 databaseCode: GX1 dateStart: 19950101 isFulltext: true titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php providerName: Geneva Foundation for Medical Education and Research – providerCode: PRVAQN databaseName: PubMed Central (Open Access) customDbUrl: eissn: 2187-5626 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0027048 issn: 0915-5287 databaseCode: RPM dateStart: 20130101 isFulltext: true titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/ providerName: National Library of Medicine – providerCode: PRVFZP databaseName: Scholars Portal Journals: Open Access customDbUrl: eissn: 2187-5626 dateEnd: 20250731 omitProxy: true ssIdentifier: ssj0027048 issn: 0915-5287 databaseCode: M48 dateStart: 20130501 isFulltext: true titleUrlDefault: http://journals.scholarsportal.info providerName: Scholars Portal |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELf2gQQS4nNA-KiMBHtBKfmwE-cBwUCMCWnTHlapPEV2Ymut0jRrWkH_C_5k7uIkozAmXqJEPbuK72z_Lr67HyGvADMYzUTkCh5rlylfuMro3GUBLIRoRaaJdj8-iY5G7OuYj7dIFz_fDmB9pWuHfFKjRTH8cbF-DxP-XcPeI5K302pZDwMxDAM_3K8uXKSUwqPXll9jm-zCtpUgr8MxE5femNdQa8F-ycEbE3EbFf9nhxv71Y0pQDbMxb89s8cotpzFVej07yDLm6uykuvvsih-28EO75E7LfSkB9ZW7pMtXT4gd09bRdEzW1_gIfkJd7QtWVXQRRctdz6p6NzQJSi_xjOrmrYxXnS2qqFDiikSyERBZZnTJozStqQ2FZKqSbZGuYWcVbSjeqKTkmY2SQVa5vgpEWU1kocXazqD_aveI6PDz2efjtyWuMHNIoCPLleKi8D4HoIRcFCFANCV68xI7XmZ8vI4C6U2npECa9EkXEeKS2F8o2UgPRU-IjvlvNRPCGVGeokMFA9VzJRWioWaZzyOZSIlOEMOedOpJ83aquZIrlGk6N2AMlNUZhqIFJXpkNe9dGWrefxD7qPVdC_VzuNeCtwmuNonDJKLOOtlMF8OFh2HfNiwkrQz7jSTYnrZFN1e6M5jUfPfeEkCWPbBkXTIy86wUpj2eJYjSz1f1SnmvANYZElwrUwC0xBwikMeW2Ps3yeAdRgpjR0Sb5hpL4Blxzd_KSfnTflxgNiA26Hlfm_Q1w7m0_94iWfkFo6F_bb1nOwsFyv9AtDeUg3I9pexP2jm7oDsjk5OD779At2EXYI |
| linkProvider | Scholars Portal |
| linkToUnpaywall | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3rb9MwELdGhwQIMd6El4wEfEFJ83LifGOgTRMS0z6s0vhk2Ym9tbRp1LRC5a_gT-YudgPlMSHxJW3Vs9P6zne_i-9ByEvADEanPPM5y7Wfqoj7yujKT2NQhChFpot2_3icHY3SD2fsbIccbHJhMKxyArjoXONLcD4PJs3QLeJw0izbYcyHUQRXgZ-AyVHmZywdiqYyV8huxgCSD8ju6Phk_1NXZy9i4Gx1jfLAmuU-2PvMBcAzXnRTBjEPkjhKtkzTVfsrbpCbM3tiYitX_AmI_h5PeW1VN3L9RU6nPxmrwz0bVNJ2NQ4xRuVzsFqqoPz6SwXI_16H2-SWg7N03w65Q3Z0fZfsnTjm01Nbs-Ae-QbvqCuDNaWLTQTexbihc0OXIFAtnoO11MWN0dmqhQkppl1gdwsq64p2oZl2JLXplVSNyzXSLeSsoZv2UXRc09ImvsDICh9PIq3GhuTTNZ2BTWzvk9Hhwen7I981g_DLDCCpz5RiPDZRiAAHnF7OAchVujRSh2GpwiovE6lNaCTH-jYF05likpvIaBnLUCUPyKCe1_oRoamRYSFjxRKVp0orlSaalSzPZSElOFgeebORA1G6SunYsGMq0GMCqemWXMDSo9R45FVP3dgKIX-he2cZ2lM5dvZU4Io5dgpkpwB29jSYgweKzCNvt8RROI3TilLyyY-h6ErDdGGadffGSxGDKQHn1CMvNhIsQJXg-ZCs9XzVCsyjBwCaFvGlNAVsbcA-Hnlopb7_PzHodmyT7JF8az_0BFjKfPubenzRlTQH2A6-AIx83e-cSxfz8b8SPiHXu63RPTR7SgbLxUo_Axi5VM-dkvgODxp3Fw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+temporal+relationship+of+thresholds+between+muscle+activity+and+ventilation+during+bicycle+ramp+exercise+in+community+dwelling+elderly+males&rft.jtitle=Journal+of+physical+therapy+science&rft.au=Sasaki%2C+Kentaro&rft.au=Kimura%2C+Tsuyoshi&rft.au=Kojima%2C+Satoshi&rft.au=Higuchi%2C+Hiroyuki&rft.date=2016&rft.issn=0915-5287&rft.volume=28&rft.issue=11&rft.spage=3213&rft.epage=3219&rft_id=info:doi/10.1589%2Fjpts.28.3213&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0915-5287&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0915-5287&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0915-5287&client=summon |