Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis - Shao, Haifeng; Burrage, Lindsay C; Sinasac, David S; Hill, Annie E; Ernest, Sheila R; O'Brien, William; Courtland, Hayden-William; Jepsen, Karl J; Kirby, Andrew; Kulbokas, E.J; Daly, Mark J; Broman, Karl W; et al. (Proceedings of the National Academy of Sciences - PNAS, 2008)
Keywords: Animals; Architecture; Biological Sciences; Blood; Body Weight - genetics; Bone; Chromosome substitution; Chromosomes; Disease - genetics; Effects; Epistasis; Epistasis, Genetic; Evolutionary genetics; Genes; genetic variation; Genetics; Genomes; Genotype & phenotype; Human genetics; Inbreeding; loci; Medical genetics; Mice; Mice, Congenic; Mice, Inbred C57BL; Phenotype; Phenotypic traits; phenotypic variation; Phenotypic variations; Physiology; Polygenic inheritance; Quantitative Trait Loci; Quantitative traits; Rats; Rodents