Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation - Stauch, Benjamin; Hofmann, Henning; Perković, Mario; Weisel, Martin; Kopietz, Ferdinand; Cichutek, Klaus; Münk, Carsten; Schneider, Gisbert (Proceedings of the National Academy of Sciences - PNAS, 2009)
Keywords: Algorithms; Antiviral activity; antiviral properties; Antivirals; APOBEC Deaminases; Binding Sites; Biochemistry; Biological Sciences; Capsid - metabolism; Cell Line; Cytidine Deaminase; Cytosine Deaminase - chemistry; Cytosine Deaminase - metabolism; Deamination; Dimerization; Dimers; Encapsidation; Genetic mutation; genome; Genomes; Genomics; HIV 1; Human immunodeficiency virus 1; Humans; Immunity; Immunoblotting; loci; Models, Molecular; Mutant Proteins - metabolism; Mutation; Packaging; Plasmids; Protein Multimerization; Protein Processing, Post-Translational; Protein Structure, Secondary; Proteins; Retrovirus; Reverse transcription; Ribonucleic acid; RNA; RNA - metabolism; Simian immunodeficiency virus; vif Gene Products, Human Immunodeficiency Virus - metabolism; Vif protein; virion; Virions; Viruses