Pathobiont-driven antibody sialylation through IL-10 undermines vaccination - Tsai, Chih-Ming; Hajam, Irshad A.; Caldera, J.R.; Chiang, Austin W.T.; Gonzalez, Cesia; Du; Choudhruy, Biswa; Li, Haining; Suzuki, Emi; Askarian, Fatemeh; Clark, Ty’Tianna; Lin, Brian; et al. (The Journal of clinical investigation, 2024)
Keywords: Animals; Antibodies, Bacterial - immunology; B cells; B-Lymphocytes - immunology; Care and treatment; Diagnosis; Female; Glycosylation; Health aspects; Humans; Immunology; Infectious disease; Interleukin-10; Interleukin-10 - immunology; Interleukin-10 - metabolism; Mice; Sialic acids; Sialyltransferases - immunology; Sialyltransferases - metabolism; Staphylococcal Infections - immunology; Staphylococcal Infections - microbiology; Staphylococcal Infections - prevention & control; Staphylococcal Vaccines - immunology; Staphylococcus aureus - immunology; Staphylococcus aureus infections; STAT3 Transcription Factor - immunology; STAT3 Transcription Factor - metabolism; Testing; Vaccination; United States; Infectious disease; Adaptive immunity; Immunology; Imprinting