Thiophene derivative inflicts cytotoxicity via an intrinsic apoptotic pathway on human acute lymphoblastic leukemia cells - Swain, Risa Mia; Sanchez, Anahi; Gutierrez, Denisse A.; Varela-Ramirez, Armando; Aguilera, Renato J. (PloS one, 2023)
Keywords: Acute lymphoblastic leukemia; Anticancer properties; Antifungal agents; Antineoplastic Agents - pharmacology; Antineoplastic drugs; Antitumor activity; Apoptosis; Biology and Life Sciences; Blood cancer; Cancer; Carbonyl compounds; Carbonyls; Care and treatment; Cell death; Cell Line, Tumor; Cell Proliferation; Cytotoxicity; Depolarization; Diagnosis; Drug Screening Assays, Antitumor; Estrogen receptors; Estrogens; Evaluation; Flow cytometry; Fungicides; Health aspects; Health care disparities; Heterocyclic compounds; High-throughput screening; Humans; Kinases; Leukemia; Libraries; Lymphatic leukemia; Lymphoma; Medicine and Health Sciences; Microorganisms; Mitochondria; Molecular Structure; Non-Hodgkin's lymphomas; Penicillin; Phosphatidylserine; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Reactive oxygen species; Research and Analysis Methods; Scientific equipment and supplies industry; Structure-Activity Relationship; Thiophene; Thiophenes; Thiophenes - pharmacology; Tumor cell lines; United States; St Louis Missouri; United States--US