The Poisson distribution model fits UMI-based single-cell RNA-sequencing data - Pan, Yue; Landis, Justin T.; Moorad, Razia; Wu, Di; Marron, J. S.; Dittmer, Dirk P. (BMC bioinformatics, 2023)
Keywords: Accuracy; Algorithms; Analysis; Approximation; Bioinformatics; Biomedical and Life Sciences; Cluster Analysis; Clustering; Clustering (Computers); Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Computer simulation; Data representation; Electronic data processing; Gene Expression Profiling - methods; Gene sequencing; Genes; Heterogeneity; Hypotheses; Hypothesis testing; Information management; Life Sciences; Mathematical models; Methods; Microarrays; Modelling; Optimization; Parameter estimation; Parameters; Poisson Distribution; Probability; Representations; Ribonucleic acid; RNA; RNA - genetics; RNA sequencing; RNA-seq; Sequence Analysis, RNA - methods; Single cell; Single-Cell Analysis - methods; Single-cell technologies; Statistical models; United States; Data representation; Single cell; RNA-seq; Poisson distribution