In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS) - Dharpure, Rupal; Pramanik, Subrata; Pradhan, Ajay (Archives of Toxicology, 2023)
Keywords: Amyloid; Amyloid - chemistry; Amyloid - metabolism; Amyloidogenesis; Binding; Binding energy; Biomedical and Life Sciences; Biomedicine; Carbon; Cerebrospinal fluid; Computer applications; computer simulation; Destabilization; Disruption; energy; Environmental Health; Environmental Pollutants; Fluorocarbons; Functional groups; H-bond and Hydrophobic interactions; Hypothyroidism; In Silico; Molecular chains; Molecular interactions; Molecular modelling; Occupational Medicine/Industrial Medicine; Perfluoroalkyl & polyfluoroalkyl substances; Pharmacology/Toxicology; Pollutants; Prealbumin; Prealbumin - metabolism; Protein transport; Proteins; Sulfur; Thyroid; Thyroid Gland; Thyroid Gland - metabolism; Thyroid hormone receptors; Thyroid Hormones; Thyroid Hormones - metabolism; Thyroid toxicity; Thyroxine; Transthyretin; Amyloidogenesis; Molecular interactions; Binding energy; Transthyretin; H-bond and Hydrophobic interactions; Hypothyroidism; Thyroid toxicity