磁共振体素内不相干运动成像在宫颈癌中的初步应用

目的初步评价1.5TMR体素内不相干运动成像参数在宫颈癌中的应用价值。方法搜集经术后或活检病理证实的24例宫颈癌患者,另招募30名健康女性作为对照组,均行IVIM成像(b=0~1000s/mm2),并分析参数(f、D*、D、ADC)。两组间分别进行独立样本t检验,采用受试者工作特征曲线下面积评估上述参数值鉴别宫颈癌的能力。结果宫颈癌组的参数f、D*、D、ADC平均值分别为(25.83±6.12)%,(16.83±4.02)×10-3mm2/s,(0.95±0.15)×10-3mm2/s,(1.05±0.17)×10-3mm2/s。正常健康女性宫颈纤维间质的上述参数平均值分别为(40.87±9....

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Published in影像诊断与介入放射学 Vol. 26; no. 5; pp. 398 - 403
Main Author 王红燕;王建良;翁丽强;沈纪芳;吴志娟;高迁
Format Journal Article
LanguageChinese
Published 昆山市第一人民医院放射科, 江苏昆山,215300 2017
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ISSN1005-8001
DOI10.3969/j.issn.1005-8001.2017.05.009

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Summary:目的初步评价1.5TMR体素内不相干运动成像参数在宫颈癌中的应用价值。方法搜集经术后或活检病理证实的24例宫颈癌患者,另招募30名健康女性作为对照组,均行IVIM成像(b=0~1000s/mm2),并分析参数(f、D*、D、ADC)。两组间分别进行独立样本t检验,采用受试者工作特征曲线下面积评估上述参数值鉴别宫颈癌的能力。结果宫颈癌组的参数f、D*、D、ADC平均值分别为(25.83±6.12)%,(16.83±4.02)×10-3mm2/s,(0.95±0.15)×10-3mm2/s,(1.05±0.17)×10-3mm2/s。正常健康女性宫颈纤维间质的上述参数平均值分别为(40.87±9.84)%,(17.64±4.80)×10-3mm2/s,(1.00±0.28)×10-3mm2/s,(1.56±0.45)×10-3mm2/s;外侧肌层分别为(36.00±5.99)%,(17.69±4.37)×10-3mm2/s,(1.24±0.20)×10-3mm2/s,(1.83±0.54)×10-3mm2/s。除D*值外,f、D、ADC值在纤维间质和外侧肌层间差异均有统计学意义(P<0.05)。除D*、D值外,f、ADC值鉴别宫颈癌和纤维间质差异有统计学意义(P<0.01),其ROC曲线下面积分别为:0.923、0.912;除D*值外,f、D、ADC值鉴别宫颈癌和外侧肌层差异均有统计学意义(P<0.01),其ROC曲线下面积分别为:0.881、0.887、0.974。结论1.5TMR体素内不相干运动成像参数在宫颈癌诊断中具有应用价值,并能有效区分正常宫颈纤维间质和外侧肌层。
Bibliography:Intravoxel incoherent motion;Cervical cancer;Magnetic resonance imaging
44-1391/R
Objective To evaluate the intravoxel incoherent motion(IVIM)imaging parameters on1.5T MR system for diagnosing cervical carcinoma.Methods24patients with pathologically confirmed cervical cancer and30healthy women underwent IVIM imaging with b values of0-1000s/mm2.The parameters including f,D*,D,and ADC were determined and compared between the two groups using independent samples t test.The usefulness of these parameters for diagnosing cervical cancer was evaluated by areas under the receiver operating characteristic(ROC)curves.Results The average f,D and ADC values were significantly different(P<0.05)between that of normal fibrous stroma(40.87±9.84%,1.00±0.28×10-3mm2/s,1.56±0.45×10-3mm2/s)and lateral muscle layer(36.00±5.99%,1.24±0.20×10-3mm2/s,1.83±0.54×10-3mm2/s)whereas the D*values were not significantly different between that of normal fibrous stroma(17.64±4.80×10-3mm2/s)and normal lateral muscle layer(17.69±4.37×10-3mm2/s)
ISSN:1005-8001
DOI:10.3969/j.issn.1005-8001.2017.05.009