Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages - Håversen, Liliana; Danielsson, Kristina Norén; Fogelstrand, Linda; Wiklund, Olov (Atherosclerosis, 2009)
Keywords: Atherosclerosis; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; biosynthesis; Blood and lymphatic vessels; Cardiology. Vascular system; Cardiovascular; Cardiovascular system; Cell Line; Cell Line, Tumor; Ceramide; Ceramides; Ceramides - biosynthesis; Cytokines; Cytokines - genetics; Cytokines - metabolism; Cytokines - secretion; cytology; Dermatologi och venereologi; Dermatology and Venereal Diseases; Diabetes; drug effects; Fatty Acids; Fatty Acids - pharmacology; genetics; Humans; Interleukin-1beta; Interleukin-1beta - genetics; Interleukin-1beta - metabolism; Interleukin-1beta - secretion; Interleukin-8; Interleukin-8 - genetics; Interleukin-8 - metabolism; Interleukin-8 - secretion; JNK Mitogen-Activated Protein Kinases; JNK Mitogen-Activated Protein Kinases - metabolism; Lauric Acids; Lauric Acids - pharmacology; Leukemia; Linoleic Acid; Linoleic Acid - pharmacology; Macrophages; Medical sciences; Messenger; metabolism; Microbiology in the Medical Area; Mikrobiologi inom det medicinska området; Monocytes; Monocytes - cytology; Monocytes - drug effects; Monocytes - physiology; Myeloid Differentiation Factor 88; Myeloid Differentiation Factor 88 - genetics; Myeloid Differentiation Factor 88 - metabolism; Myristic Acid; Myristic Acid - pharmacology; p38 Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases - metabolism; Palmitate; Palmitic Acid; Palmitic Acid - pharmacology; Palmitoyl Coenzyme A; Palmitoyl Coenzyme A - metabolism; pharmacology; Pharmacology. Drug treatments; physiology; Proinflammatory cytokines; RNA; RNA, Messenger - metabolism; RNA, Small Interfering; secretion; Serine palmitoyltransferase; Small Interfering; Stearate; Stearic Acids; Stearic Acids - pharmacology; Transcription Factor AP-1; Transcription Factor AP-1 - metabolism; Tumor; Tumor Necrosis Factor-alpha; Tumor Necrosis Factor-alpha - genetics; Tumor Necrosis Factor-alpha - metabolism; Tumor Necrosis Factor-alpha - secretion; Vasodilator agents. Cerebral vasodilators; Serine palmitoyltransferase; Palmitate; Atherosclerosis; Stearate; Ceramide; Diabetes; Proinflammatory cytokines; Macrophages; Endocrinopathy; Human; Long chain; Diabetes mellitus; Serine; Cytokine; Sphingolipid; Lipids