A computational grid-to-place-cell transformation model indicates a synaptic driver of place cell impairment in early-stage Alzheimer’s Disease - Ness, Natalie; Schultz, Simon R. (PLoS computational biology, 2021)
Keywords: Abnormalities; Alzheimer's disease; Animal models; Biology and Life Sciences; Cognitive ability; Competition; Computational grids; Computational neuroscience; Development and progression; Feedback; Firing rate; Health aspects; Impairment; Medicine and Health Sciences; Memory; Neurodegeneration; Neurodegenerative diseases; Presenilin 1; Pyramidal cells; Representations; Research and Analysis Methods; Simulation; Stability; Synapses; Transformation; Transformations (mathematics); United Kingdom