Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer - Kel, Alexander; Boyarskikh, Ulyana; Stegmaier, Philip; Leskov, Leonid S.; Sokolov, Andrey V.; Yevshin, Ivan; Mandrik, Nikita; Stelmashenko, Daria; Koschmann, Jeannette; Kel-Margoulis, Olga; Krull, Mathias; Martínez-Cardús, Anna; et al. (BMC bioinformatics, 2019)
Keywords: Age; Algorithms; Artificial intelligence; Binding sites; Biofeedback training; Bioinformatics; Biomarkers; Biomedical and Life Sciences; Blood; Cancer; Carcinogens; Circulating DNA; Colorectal cancer; Colorectal carcinoma; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Consortia; CpG islands; Data analysis; Data processing; Deoxyribonucleic acid; Diagnosis; DNA; DNA methylation; Enhancers; Epigenetics; Feedback; Feedback loops; Gene expression; Gene regulation; Genes; Genetic algorithms; Genetic aspects; Genetic markers; Genomes; Genomics; Health aspects; Information sources; Learning algorithms; Life Sciences; Machine learning; Methylation; Microarrays; Multi-omics analysis; Myc protein; Patients; Plasma; Positive feedback; Prognostic biomarkers; Regulatory sequences; Ribonucleic acid; RNA; Searching; Signal transduction; Software; Statistical analysis; Statistical methods; Topology; Transcription factor binding sites; Transcription factors; Transduction; Walking; Web services; Germany; Prognostic biomarkers; Signal transduction; Genetic algorithm; Multi-omics analysis; Colorectal cancer; DNA methylation; Transcription factor binding sites; Circulating DNA