The pan-cancer landscape of prognostic germline variants in 10,582 patients - Chatrath, Ajay; Przanowska, Roza; Kiran, Shashi; Su, Zhangli; Saha, Shekhar; Wilson, Briana; Tsunematsu, Takaaki; Ahn, Ji-Hye; Lee, Kyung Yong; Paulsen, Teressa; Sobierajska, Ewelina; Kiran, Manjari; et al. (Genome medicine, 2020)
Keywords: Analysis; Bioinformatics; Biomarkers, Tumor - genetics; Biomedical and Life Sciences; Biomedicine; Cancer; Cancer biology; Cancer genetics; Cancer patients; Cancer Research; Cancer therapies; Clinical outcomes; Gene expression; Genes; Genetic aspects; Genetic polymorphisms; Genetic research; Genetic Testing - statistics & numerical data; Genomes; Genomics; Germ-Line Mutation; Germline variants; Human Genetics; Humans; Medical research; Medical screening; Medicine/Public Health; Metabolomics; Mutation; Neoplasms - genetics; Neoplasms - pathology; Oncogene Proteins - genetics; Oncology; Pan-cancer; Patients; Physicians; Polymorphism, Single Nucleotide; Power (Philosophy); Prognosis; Protein structure; Quality control; Quantitative Trait Loci; Regression analysis; Single nucleotide polymorphism; Single nucleotide polymorphisms; Studies; Survival analysis; Systems Biology; Tumor suppressor; Tumor suppressor genes; Tumor Suppressor Proteins - genetics; Tumors; Survival analysis; Non-synonymous mutation; Germline variants; Cancer biology; Pan-cancer; Oncogene; Single nucleotide polymorphism; eQTL; Driver gene; Tumor suppressor