脊柱推拿对腰椎间盘突出症患者脑功能活动的影响

目的:观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法:招募11例腰椎间盘突出症患者,8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗,并在脊柱推拿治疗前、后对患者进行颅脑功能核磁共振成像检测,评估患者脑功能活动的改变及与疗效关系。结果:4例腰椎间盘突出症患者脊柱推拿治疗有效,4例无效。脊柱推拿有效患者治疗前、后产生视觉模拟评分(VAS)为50分时的疼痛压力值分别为(7.43±1.47)kg和(10.53±0.55)kg(P<0.05),而无效患者的则无明显差异(P>0.05)。颅脑功能核磁共振成像检测结果提示,脊柱推拿治疗有效患者的脑功能活动以抑制为主,抑制区域主要位于右侧前...

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Published in浙江大学学报(医学版) no. 2; pp. 124 - 130
Main Author 元唯安 沈知彼 薛利 谭文莉 程英武 詹松华 詹红生
Format Journal Article
LanguageChinese
Published 上海市中医药研究院骨伤科研究所,上海201203%复旦大学计算机科学技术学院,上海,201203%上海中医药大学附属曙光医院放射科,上海,201203%上海市中医药研究院推拿研究所,上海,200437 2015
上海中医药大学附属曙光医院石氏伤科医学中心,上海201203
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ISSN1008-9292
DOI10.3785/j.issn.1008-9292.2015.03.002

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Summary:目的:观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法:招募11例腰椎间盘突出症患者,8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗,并在脊柱推拿治疗前、后对患者进行颅脑功能核磁共振成像检测,评估患者脑功能活动的改变及与疗效关系。结果:4例腰椎间盘突出症患者脊柱推拿治疗有效,4例无效。脊柱推拿有效患者治疗前、后产生视觉模拟评分(VAS)为50分时的疼痛压力值分别为(7.43±1.47)kg和(10.53±0.55)kg(P<0.05),而无效患者的则无明显差异(P>0.05)。颅脑功能核磁共振成像检测结果提示,脊柱推拿治疗有效患者的脑功能活动以抑制为主,抑制区域主要位于右侧前额叶及小脑区域;而脊柱推拿治疗无效患者的脑功能活动以增强为主。结论:脊柱推拿能够影响腰椎间盘突出症患者的脑功能活动,其治疗有效患者的抑制区域主要在额叶及小脑。
Bibliography:33-1248/R
Objective: To investigate the effects of spinal manipulation ( SM) on brain functional activity in patients with lumbar disc herniation ( LDH ) .Methods:Eleven patients with LDH were recruited in the study .All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated .All patients received brain functional magnetic resonance imaging ( fMRI ) scans before and after SM treatment.Results: Three subjects dropped out and 8 subjects completed the study , among whom 4 cases were effective and 4 ineffective after SM treatment .The required pressure value producing the same level ( VAS 50 ) pain was ( 7 .43 ±1 .47 ) kg and (10.53 ±0.55) kg before and after SM treatment in effective patients ( P〈0.05);however , there was no significant difference in ineffective patients ( P〉0 .05 ) . Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited , the inhibited areas were located in the right side of prefrontal cortex and cerebellum;wh
ISSN:1008-9292
DOI:10.3785/j.issn.1008-9292.2015.03.002