脊柱推拿对腰椎间盘突出症患者脑功能活动的影响
目的：观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法：招募11例腰椎间盘突出症患者，8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗，并在脊柱推拿治疗前、后对患者进行颅脑功能核磁共振成像检测，评估患者脑功能活动的改变及与疗效关系。结果：4例腰椎间盘突出症患者脊柱推拿治疗有效，4例无效。脊柱推拿有效患者治疗前、后产生视觉模拟评分（VAS）为50分时的疼痛压力值分别为（7.43±1.47）kg和（10.53±0.55）kg（P＜0.05），而无效患者的则无明显差异（P＞0.05）。颅脑功能核磁共振成像检测结果提示，脊柱推拿治疗有效患者的脑功能活动以抑制为主，抑制区域主要位于右侧前...
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| Published in | 浙江大学学报（医学版） no. 2; pp. 124 - 130 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
上海市中医药研究院骨伤科研究所，上海201203%复旦大学计算机科学技术学院,上海,201203%上海中医药大学附属曙光医院放射科,上海,201203%上海市中医药研究院推拿研究所,上海,200437
2015
上海中医药大学附属曙光医院石氏伤科医学中心，上海201203 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1008-9292 |
| DOI | 10.3785/j.issn.1008-9292.2015.03.002 |
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| Abstract | 目的：观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法：招募11例腰椎间盘突出症患者，8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗，并在脊柱推拿治疗前、后对患者进行颅脑功能核磁共振成像检测，评估患者脑功能活动的改变及与疗效关系。结果：4例腰椎间盘突出症患者脊柱推拿治疗有效，4例无效。脊柱推拿有效患者治疗前、后产生视觉模拟评分（VAS）为50分时的疼痛压力值分别为（7.43±1.47）kg和（10.53±0.55）kg（P＜0.05），而无效患者的则无明显差异（P＞0.05）。颅脑功能核磁共振成像检测结果提示，脊柱推拿治疗有效患者的脑功能活动以抑制为主，抑制区域主要位于右侧前额叶及小脑区域；而脊柱推拿治疗无效患者的脑功能活动以增强为主。结论：脊柱推拿能够影响腰椎间盘突出症患者的脑功能活动，其治疗有效患者的抑制区域主要在额叶及小脑。 |
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| AbstractList | R244; 目的：观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法：招募11例腰椎间盘突出症患者，8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗，并在脊柱推拿治疗前、后对患者进行颅脑功能核磁共振成像检测，评估患者脑功能活动的改变及与疗效关系。结果：4例腰椎间盘突出症患者脊柱推拿治疗有效，4例无效。脊柱推拿有效患者治疗前、后产生视觉模拟评分（VAS）为50分时的疼痛压力值分别为（7.43±1.47）kg和（10.53±0.55）kg（P＜0.05），而无效患者的则无明显差异（P＞0.05）。颅脑功能核磁共振成像检测结果提示，脊柱推拿治疗有效患者的脑功能活动以抑制为主，抑制区域主要位于右侧前额叶及小脑区域；而脊柱推拿治疗无效患者的脑功能活动以增强为主。结论：脊柱推拿能够影响腰椎间盘突出症患者的脑功能活动，其治疗有效患者的抑制区域主要在额叶及小脑。 目的：观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法：招募11例腰椎间盘突出症患者，8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗，并在脊柱推拿治疗前、后对患者进行颅脑功能核磁共振成像检测，评估患者脑功能活动的改变及与疗效关系。结果：4例腰椎间盘突出症患者脊柱推拿治疗有效，4例无效。脊柱推拿有效患者治疗前、后产生视觉模拟评分（VAS）为50分时的疼痛压力值分别为（7.43±1.47）kg和（10.53±0.55）kg（P＜0.05），而无效患者的则无明显差异（P＞0.05）。颅脑功能核磁共振成像检测结果提示，脊柱推拿治疗有效患者的脑功能活动以抑制为主，抑制区域主要位于右侧前额叶及小脑区域；而脊柱推拿治疗无效患者的脑功能活动以增强为主。结论：脊柱推拿能够影响腰椎间盘突出症患者的脑功能活动，其治疗有效患者的抑制区域主要在额叶及小脑。 |
| Abstract_FL | Objective: To investigate the effects of spinal manipulation ( SM) on brain functional activity in patients with lumbar disc herniation ( LDH ) .Methods:Eleven patients with LDH were recruited in the study .All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated .All patients received brain functional magnetic resonance imaging ( fMRI ) scans before and after SM treatment.Results: Three subjects dropped out and 8 subjects completed the study , among whom 4 cases were effective and 4 ineffective after SM treatment .The required pressure value producing the same level ( VAS 50 ) pain was ( 7 .43 ±1 .47 ) kg and (10.53 ±0.55) kg before and after SM treatment in effective patients ( P<0.05);however , there was no significant difference in ineffective patients ( P>0 .05 ) . Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited , the inhibited areas were located in the right side of prefrontal cortex and cerebellum;while the brain functional activity was generally enhanced in ineffective patients.Conclusion:SM can affect the brain functional activity of patients with LDH , the inhibited areas is mainly located in prefrontal cortex and cerebellum when SM treatment is effective . |
| Author | 元唯安 沈知彼 薛利 谭文莉 程英武 詹松华 詹红生 |
| AuthorAffiliation | 上海中医药大学附属曙光医院石氏伤科医学中心,上海201203 上海市中医药研究院骨伤科研究所,上海201203 复旦大学计算机科学技术学院,上海201203 上海中医药大学附属曙光医院放射科,上海201203 上海市中医药研究院推拿研究所,上海200437 |
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| Author_FL | CHENG Ying-wu ZHAN Song-hua ZHAN Hong-sheng TAN Wen-li YUAN Wei-an SHEN Zhi-bi XUE Li |
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| DocumentTitleAlternate | Effect of spinal manipulation on brain functional activity in patients with lumbar disc herniation |
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| Keywords | Brain Treatment outcome 椎间盘移位按/摩疗法 Intervertebral disk displacement /AN MO LIAO FA Lumbar vertebrae 腰椎 脑 疼痛 治疗结果 Pain 磁共振成像 Magnetic resonance imaging 推拿,脊柱 Manipulation,spinal |
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| Notes | 33-1248/R Objective： To investigate the effects of spinal manipulation （ SM） on brain functional activity in patients with lumbar disc herniation （ LDH ） .Methods：Eleven patients with LDH were recruited in the study .All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated .All patients received brain functional magnetic resonance imaging （ fMRI ） scans before and after SM treatment.Results： Three subjects dropped out and 8 subjects completed the study , among whom 4 cases were effective and 4 ineffective after SM treatment .The required pressure value producing the same level （ VAS 50 ） pain was （ 7 .43 ±1 .47 ） kg and （10.53 ±0.55） kg before and after SM treatment in effective patients （ P〈0.05）;however , there was no significant difference in ineffective patients （ P〉0 .05 ） . Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited , the inhibited areas were located in the right side of prefrontal cortex and cerebellum;wh |
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| Publisher | 上海市中医药研究院骨伤科研究所，上海201203%复旦大学计算机科学技术学院,上海,201203%上海中医药大学附属曙光医院放射科,上海,201203%上海市中医药研究院推拿研究所,上海,200437 上海中医药大学附属曙光医院石氏伤科医学中心，上海201203 |
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| Snippet | 目的：观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法：招募11例腰椎间盘突出症患者，8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗，并在脊柱推拿... R244; 目的：观察脊柱推拿治疗对腰椎间盘突出症患者脑功能活动的影响。方法：招募11例腰椎间盘突出症患者，8例受试者完成了研究。所有患者接受6次腰部脊柱推拿治疗，并在脊... |
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| SubjectTerms | 推拿,脊柱 椎间盘移位按/摩疗法 治疗结果 疼痛 磁共振成像 脑 腰椎 |
| Title | 脊柱推拿对腰椎间盘突出症患者脑功能活动的影响 |
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