Markers of Apoptosis Predict Cardiovascular Outcomes and Point to ‘Response to Injury’ as a Common Pathway Leading to Diabetes and Cardiovascular Events

Saved in:
Bibliographic Details
Published inEBioMedicine Vol. 28; no. C; pp. 19 - 20
Main Authors Hartley, Adam, Haskard, Dorian, Khamis, Ramzi
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.02.2018
Elsevier
Subjects
Online AccessGet full text
ISSN2352-3964
2352-3964
DOI10.1016/j.ebiom.2018.01.003

Cover

Author Khamis, Ramzi
Haskard, Dorian
Hartley, Adam
AuthorAffiliation National Heart and Lung Institute, Imperial College London, United Kingdom
AuthorAffiliation_xml – name: National Heart and Lung Institute, Imperial College London, United Kingdom
Author_xml – sequence: 1
  givenname: Adam
  surname: Hartley
  fullname: Hartley, Adam
– sequence: 2
  givenname: Dorian
  surname: Haskard
  fullname: Haskard, Dorian
– sequence: 3
  givenname: Ramzi
  surname: Khamis
  fullname: Khamis, Ramzi
  email: r.khamis@imperial.ac.uk
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29398600$$D View this record in MEDLINE/PubMed
BookMark eNqFkt9u0zAYxSM0xMbYEyAhX3LTYsd2_ggxaSoDKhWt4s-15ThfO2eJXWynqHd7DJB4uj0JzlqmbRLqVRL7nN-x853nyYGxBpLkJcFjgkn2phlDpW03TjEpxpiMMaZPkqOU8nREy4wd3Hs_TE68bzDGhLO4WDxLDtOSlkWG8VHy57N0V-A8sgt0trKrYL32aO6g1iqgiXS1tmvpVd9Khy76oGwHHklTo7nVJqBg0c31ry_gV9Z4GD6npund5ub6N5JRiCa266xBcxkuf8oNmoGstVkOwvdaVhB2tEdJ52swwb9Ini5k6-Fk9zxOvn84_zb5NJpdfJxOzmYjldE0jBjjwMqCFjlARSCnwClUmcIKp3WaszxjJGeSZGWdxZvXJCUKc7KoeL5IgXB6nEy33NrKRqyc7qTbCCu1uF2wbimkC1q1ILK8rhShPCsoZpTIiilZVjmHlAFOqyyyTresVV91UKt4DyfbB9CHO0ZfiqVdC15QzjmJgNc7gLM_evBBdNoraFtpwPZekLJkNM6ODlmv7mfdhfwbbxTQrUA5672DxZ2EYDH0SDTitkdi6JHARERTdJWPXEoHGbQdDqzbPd53Wy_Eea01OOGVBqNinxyoEH-o3uM_feRXrTZayfYKNuAb2zsTqyCI8KnA4uvQ8qHkJM5j8EfA2_8D9sb_BctCEHI
CitedBy_id crossref_primary_10_1136_bmjopen_2022_067605
Cites_doi 10.1016/j.ebiom.2016.06.012
10.1056/NEJMoa1701488
10.2337/dc14-0396
10.1073/pnas.1421227112
10.1161/01.ATV.0000122852.22604.78
10.1038/nrneph.2017.51
10.1016/j.ebiom.2017.11.023
10.3389/fimmu.2016.00099
10.1111/j.1365-2796.1993.tb00647.x
ContentType Journal Article
Copyright 2018 The Authors
The Authors
2018 The Authors 2018
Copyright_xml – notice: 2018 The Authors
– notice: The Authors
– notice: 2018 The Authors 2018
DBID 6I.
AAFTH
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
DOA
DOI 10.1016/j.ebiom.2018.01.003
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 2352-3964
EndPage 20
ExternalDocumentID oai_doaj_org_article_67dbc1356830431ab4ca9b75e24e02b6
PMC5835551
29398600
10_1016_j_ebiom_2018_01_003
S2352396418300033
1_s2_0_S2352396418300033
Genre Comment
Journal Article
GrantInformation_xml – fundername: British Heart Foundation
  grantid: FS/17/16/32560
GroupedDBID .1-
.FO
0R~
4.4
457
53G
5VS
AAEDT
AAEDW
AAIKJ
AALRI
AAMRU
AAXUO
AAYWO
ABMAC
ACGFS
ACVFH
ADBBV
ADCNI
ADEZE
ADRAZ
ADVLN
AEUPX
AEXQZ
AFPUW
AFRHN
AFTJW
AGHFR
AIGII
AITUG
AJUYK
AKBMS
AKRWK
AKYEP
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
AOIJS
APXCP
BCNDV
EBS
EJD
FDB
GROUPED_DOAJ
HYE
HZ~
IPNFZ
KQ8
M41
M48
O9-
OK1
RIG
ROL
RPM
SSZ
Z5R
0SF
6I.
AACTN
AAFTH
AFCTW
NCXOZ
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
ID FETCH-LOGICAL-c632t-445e498387eeb1e73e53eb6c0c02d274764174a169d6293d121c051fb57f2e153
IEDL.DBID M48
ISSN 2352-3964
IngestDate Wed Aug 27 01:33:12 EDT 2025
Thu Aug 21 18:26:36 EDT 2025
Fri Sep 05 12:49:47 EDT 2025
Mon Jul 21 06:05:36 EDT 2025
Tue Jul 01 00:38:45 EDT 2025
Thu Apr 24 23:04:27 EDT 2025
Wed May 17 01:14:36 EDT 2023
Sun Feb 23 10:19:24 EST 2025
Tue Aug 26 16:43:52 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue C
Language English
License This is an open access article under the CC BY-NC-ND license.
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c632t-445e498387eeb1e73e53eb6c0c02d274764174a169d6293d121c051fb57f2e153
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Commentary-3
content type line 23
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.1016/j.ebiom.2018.01.003
PMID 29398600
PQID 1994360036
PQPubID 23479
PageCount 2
ParticipantIDs doaj_primary_oai_doaj_org_article_67dbc1356830431ab4ca9b75e24e02b6
pubmedcentral_primary_oai_pubmedcentral_nih_gov_5835551
proquest_miscellaneous_1994360036
pubmed_primary_29398600
crossref_primary_10_1016_j_ebiom_2018_01_003
crossref_citationtrail_10_1016_j_ebiom_2018_01_003
elsevier_sciencedirect_doi_10_1016_j_ebiom_2018_01_003
elsevier_clinicalkeyesjournals_1_s2_0_S2352396418300033
elsevier_clinicalkey_doi_10_1016_j_ebiom_2018_01_003
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2018-02-01
PublicationDateYYYYMMDD 2018-02-01
PublicationDate_xml – month: 02
  year: 2018
  text: 2018-02-01
  day: 01
PublicationDecade 2010
PublicationPlace Netherlands
PublicationPlace_xml – name: Netherlands
PublicationTitle EBioMedicine
PublicationTitleAlternate EBioMedicine
PublicationYear 2018
Publisher Elsevier B.V
Elsevier
Publisher_xml – name: Elsevier B.V
– name: Elsevier
References Berglund, Elmstahl, Janzon, Larsson (bb0005) 1993; 233
Halban, Polonsky, Bowden, Hawkins, Ling, Mather (bb0025) 2014; 37
Ceriello, Motz (bb0010) 2004; 24
Gistera, Hansson (bb0015) 2017; 13
Khamis, Hughes, Caga-Anan, Chang, Boyle, Kojima (bb0030) 2016; 9
Grasset, Duhlin, Agardh, Ovchinnikova, Hagglof, Forsell (bb0020) 2015; 112
Wang, Coligan, Morse (bb0045) 2016; 7
Mattisson, Björkbacka, Wigren (bb0035) 2017; 26
Ridker, Revkin, Amarenco, Brunell, Curto, Civeira (bb0040) 2017; 376
Gistera (10.1016/j.ebiom.2018.01.003_bb0015) 2017; 13
Ceriello (10.1016/j.ebiom.2018.01.003_bb0010) 2004; 24
Berglund (10.1016/j.ebiom.2018.01.003_bb0005) 1993; 233
Grasset (10.1016/j.ebiom.2018.01.003_bb0020) 2015; 112
Mattisson (10.1016/j.ebiom.2018.01.003_bb0035) 2017; 26
Wang (10.1016/j.ebiom.2018.01.003_bb0045) 2016; 7
Khamis (10.1016/j.ebiom.2018.01.003_bb0030) 2016; 9
Ridker (10.1016/j.ebiom.2018.01.003_bb0040) 2017; 376
Halban (10.1016/j.ebiom.2018.01.003_bb0025) 2014; 37
29208468 - EBioMedicine. 2017 Dec;26:187-197. doi: 10.1016/j.ebiom.2017.11.023.
References_xml – volume: 7
  start-page: 99
  year: 2016
  ident: bb0045
  article-title: Emerging functions of natural IgM and its Fc receptor FCMR in immune homeostasis
  publication-title: Front. Immunol.
– volume: 112
  start-page: E2030
  year: 2015
  end-page: 8
  ident: bb0020
  article-title: Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 376
  start-page: 1527
  year: 2017
  end-page: 1539
  ident: bb0040
  article-title: Cardiovascular efficacy and safety of bococizumab in high-risk patients
  publication-title: N. Engl. J. Med.
– volume: 13
  start-page: 368
  year: 2017
  end-page: 380
  ident: bb0015
  article-title: The immunology of atherosclerosis
  publication-title: Nat. Rev. Nephrol.
– volume: 233
  start-page: 45
  year: 1993
  end-page: 51
  ident: bb0005
  article-title: The malmo diet and cancer study. Design and feasibility
  publication-title: J. Intern. Med.
– volume: 9
  start-page: 372
  year: 2016
  end-page: 380
  ident: bb0030
  article-title: High serum immunoglobulin G and M levels predict freedom from adverse cardiovascular events in hypertension: a nested case-control substudy of the Anglo-Scandinavian cardiac outcomes trial
  publication-title: EBioMedicine
– volume: 24
  start-page: 816
  year: 2004
  end-page: 823
  ident: bb0010
  article-title: Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited
  publication-title: Arterioscler. Thromb. Vasc. Biol.
– volume: 26
  start-page: 187
  year: 2017
  end-page: 197
  ident: bb0035
  article-title: Elevated markers of death receptor-activated apoptosis are associated with increased risk for development of diabetes and cardiovascular disease
  publication-title: EBioMedicine
– volume: 37
  start-page: 1751
  year: 2014
  end-page: 1758
  ident: bb0025
  article-title: Beta-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment
  publication-title: Diabetes Care
– volume: 9
  start-page: 372
  year: 2016
  ident: 10.1016/j.ebiom.2018.01.003_bb0030
  article-title: High serum immunoglobulin G and M levels predict freedom from adverse cardiovascular events in hypertension: a nested case-control substudy of the Anglo-Scandinavian cardiac outcomes trial
  publication-title: EBioMedicine
  doi: 10.1016/j.ebiom.2016.06.012
– volume: 376
  start-page: 1527
  issue: 16
  year: 2017
  ident: 10.1016/j.ebiom.2018.01.003_bb0040
  article-title: Cardiovascular efficacy and safety of bococizumab in high-risk patients
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa1701488
– volume: 37
  start-page: 1751
  issue: 6
  year: 2014
  ident: 10.1016/j.ebiom.2018.01.003_bb0025
  article-title: Beta-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment
  publication-title: Diabetes Care
  doi: 10.2337/dc14-0396
– volume: 112
  start-page: E2030
  issue: 16
  year: 2015
  ident: 10.1016/j.ebiom.2018.01.003_bb0020
  article-title: Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1421227112
– volume: 24
  start-page: 816
  issue: 5
  year: 2004
  ident: 10.1016/j.ebiom.2018.01.003_bb0010
  article-title: Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/01.ATV.0000122852.22604.78
– volume: 13
  start-page: 368
  issue: 6
  year: 2017
  ident: 10.1016/j.ebiom.2018.01.003_bb0015
  article-title: The immunology of atherosclerosis
  publication-title: Nat. Rev. Nephrol.
  doi: 10.1038/nrneph.2017.51
– volume: 26
  start-page: 187
  year: 2017
  ident: 10.1016/j.ebiom.2018.01.003_bb0035
  article-title: Elevated markers of death receptor-activated apoptosis are associated with increased risk for development of diabetes and cardiovascular disease
  publication-title: EBioMedicine
  doi: 10.1016/j.ebiom.2017.11.023
– volume: 7
  start-page: 99
  year: 2016
  ident: 10.1016/j.ebiom.2018.01.003_bb0045
  article-title: Emerging functions of natural IgM and its Fc receptor FCMR in immune homeostasis
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2016.00099
– volume: 233
  start-page: 45
  issue: 1
  year: 1993
  ident: 10.1016/j.ebiom.2018.01.003_bb0005
  article-title: The malmo diet and cancer study. Design and feasibility
  publication-title: J. Intern. Med.
  doi: 10.1111/j.1365-2796.1993.tb00647.x
– reference: 29208468 - EBioMedicine. 2017 Dec;26:187-197. doi: 10.1016/j.ebiom.2017.11.023.
SSID ssj0001542358
Score 2.0795527
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
elsevier
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 19
SubjectTerms Advanced Basic Science
Apoptosis
Biomarkers
Cardiovascular Diseases
Diabetes Mellitus, Type 2
Humans
Internal Medicine
Receptors, Death Domain
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Na9wwEBUlUOil9LvbpkWFHmtqy7JsHdOQkJZ-LG0DuQlJHtMNwV5iLyW3_IwU-uvySzpj2cs6LcmlR9uSZWuepTd45g1jrwEKn1RlEunUo4NS6DJySBPQa3XCCQRAEDD99FkdHMoPR9nRRqkvigkL8sBh4t6qvHQ-STNVpKQDY530Vrs8AyEhFq4X2451vOFMhfxgSTmgfWW5TESpVnKUHOqDu4CS2ymwq-hFO8eSWcO21Kv3T3anv9nn1SDKjV1p_x67O9BJvhNe4z67BfUDdjsUmDx7yH5TKg4SPN5UfGfZLLumXbR8fkp_Zzq-O4lF5V9WHcIPWm7rks-bRd3xruGX5xdfQxwt0OH7-hitcHn-i1tsyCm_pKn5HHnkT3vGP4aQfGo4hNqEu10ZaY-CLNtH7HB_7_vuQTTUY4i8SkUXSZmB1EVa5IArPOQpZCk45WMfi5K8WyXRv7GJ0qVCFlEmIvH4zVcuyysBaPTHbKtuanjKOKgMtCVxtdjLuCxslSotLZSJQ3_RVzMmRnMYP4iVU82MEzNGpR2b3oaGbGjihDROZ-zNutMyaHVc3_wd2XndlIS2-xMIPzPAz9wEvxmTI0rMmMuKqy_eaHH92Pm_ukE7rCCtSUwrTGy-EX4Jvrj0kv-KPdW650CSAvm5echXI4gNLiH0X8jW0KxwKK1lqkiZaMaeBFCvJwXtqAu8hg88gftk1qZX6sWPXqY8Q3KPfPzZ_5jm5-wOvUoIl99mW93pCl4gG-zcy_7D_wMIEV2b
  priority: 102
  providerName: Directory of Open Access Journals
Title Markers of Apoptosis Predict Cardiovascular Outcomes and Point to ‘Response to Injury’ as a Common Pathway Leading to Diabetes and Cardiovascular Events
URI https://www.clinicalkey.com/#!/content/1-s2.0-S2352396418300033
https://www.clinicalkey.es/playcontent/1-s2.0-S2352396418300033
https://dx.doi.org/10.1016/j.ebiom.2018.01.003
https://www.ncbi.nlm.nih.gov/pubmed/29398600
https://www.proquest.com/docview/1994360036
https://pubmed.ncbi.nlm.nih.gov/PMC5835551
https://doaj.org/article/67dbc1356830431ab4ca9b75e24e02b6
Volume 28
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELaqIiQuiDdLoTISR4ISx3HiA0KlalXey2Ol3izbcWCrKtlusoK99WeAxK_rL2EmThZSVkXislI2fiSesf1NPPMNIY-cy2xU5FEgYwsGSibzwABMAKvVMMNAATyB6Zu34mDCXx4mhxukz4raDWC91rTDfFKT-fGTbyfLZzDhn_721XIYq45-WlnLwYnsn5faAyP05evwvg8b5hga2iacS1gQS8F7JqL17Qx2q5bUf7Bp_Q1Kz_tW_rFZ7V8jVzuUSXe8WlwnG668QS77vJPLm-QnRugA7qNVQXdm1ayp6mlNx3M8tGno7sBFlb5bNKCVrqa6zOm4mpYNbSp6dvr9g3evdXj5ojwC4Zyd_qAaClIMO6lKOgZ4-VUv6WvvqY8FOw8c39q5nvbQ97K-RSb7e592D4IuTUNgRcyagPPEcZnFWepg4Xdp7JLYGWFDG7IcjV7BwezRkZC5AHCRRyyysBQUJkkL5kAXbpPNsirdXUKdSJzUyLkWWh7mmS5iIbl2eWTAjLTFiLBeHMp2HOaYSuNY9c5qR6qVoUIZqjBC6tMRebyqNPMUHhcXf45yXhVF_u32j2r-WXXTWYk0NzaKE5HFyE6kDbdamjRxjLuQGTEivNcS1Ye4wqIMDU0v7jtdV83V_bxQkaqZCtVH1F9UX1iR0ayFmmJVs8NOHhP9u8uHvRIrWFnwuEiXrlpAV1LyWCBh0Yjc8Uq9GhSQo8zgHjzwQN0Hoza8U06_tOzlCWB-gOn3_vtVt8gVfH7vOn-fbDbzhXsAyLAx2-0XFfh99T7bbmf-L1EPZKU
linkProvider Scholars Portal
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Markers+of+Apoptosis+Predict+Cardiovascular+Outcomes+and+Point+to+%E2%80%98Response+to+Injury%E2%80%99+as+a+Common+Pathway+Leading+to+Diabetes+and+Cardiovascular+Events&rft.jtitle=EBioMedicine&rft.au=Hartley%2C+Adam&rft.au=Haskard%2C+Dorian&rft.au=Khamis%2C+Ramzi&rft.date=2018-02-01&rft.issn=2352-3964&rft.eissn=2352-3964&rft.volume=28&rft.spage=19&rft.epage=20&rft_id=info:doi/10.1016%2Fj.ebiom.2018.01.003&rft.externalDBID=ECK1-s2.0-S2352396418300033&rft.externalDocID=1_s2_0_S2352396418300033
thumbnail_m http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F23523964%2FS2352396418X00036%2Fcov150h.gif