An MRI substudy of a donepezil clinical trial in mild cognitive impairment - Schuff, Norbert; Suhy, Joyce; Goldman, Robert; Xu, Yikang; Sun, Yijun; Truran-Sacrey, Diana; Murthy, Anita (Neurobiology of aging, 2011)
Keywords: Aged; Aged, 80 and over; Amnestic MCI; Atrophy; Brain - drug effects; Brain - pathology; Cognitive decline; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - drug therapy; Cognitive Dysfunction - psychology; Donepezil; Double-Blind Method; Female; Hippocampus; Humans; Indans - pharmacology; Indans - therapeutic use; Internal Medicine; Magnetic Resonance Imaging - methods; Male; Middle Aged; Neurology; Piperidines - pharmacology; Piperidines - therapeutic use; Randomized clinical trial; Serial MRI volumetric imaging; Single-Blind Method; Surrogate marker; Whole brain analysis; Cognitive decline; Atrophy; Amnestic MCI; Randomized clinical trial; Donepezil; Surrogate marker; Whole brain analysis; Hippocampus; Serial MRI volumetric imaging