A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): A randomized, controlled non-inferiority trial - Keitel, Kristina; Kagoro, Frank; Samaka, Josephine; Masimba, John; Said, Zamzam; Temba, Hosiana; Mlaganile, Tarsis; Sangu, Willy; Rambaud-Althaus, Clotilde; Gervaix, Alain; Genton, Blaise; D’Acremont, Valérie (PLoS medicine, 2017)
Keywords: Age of Onset; Algorithms; Ambulatory care; Analysis; Anemia; Anti-Bacterial Agents - therapeutic use; Antibiotics; Antimicrobial agents; Biology and Life Sciences; Biomarkers - blood; C-reactive protein; Care and treatment; Case management; Child, Preschool; Children; Children & youth; Clinical Decision-Making; Clinical outcomes; Communicable Diseases - diagnosis; Communicable Diseases - drug therapy; Communicable Diseases - mortality; Communicable Diseases - physiopathology; Consultation; Control algorithms; Decision Support Techniques; Diagnosis, Computer-Assisted - instrumentation; Diagnosis, Differential; Disease management; Failure; Female; Fever - diagnosis; Fever - drug therapy; Fever - mortality; Fever - physiopathology; Funding; Heart Rate; Hemoglobin; Hospitals; Humans; Infant; Infections; Malaria; Male; Management tools; Medical tests; Medicine; Medicine and Health Sciences; Mobile Applications; Mortality; Nutritional Status; Patient Readmission; Patient Selection; Pediatric diseases; Pneumonia; Point of care testing; Point-of-Care Systems; Predictive Value of Tests; Prescriptions; Procalcitonin; Proteins; Public health; Randomization; Reproducibility of Results; Respiration; Risk Factors; Severity of Illness Index; Smartphone; Supervision; Tanzania; Treatment outcome; Vector-borne diseases; Tanzania; Switzerland