Empirical bayes analysis of sequencing-based transcriptional profiling without replicates - Wu, Zhijin; Jenkins, Bethany D; Rynearson, Tatiana A; Dyhrman, Sonya T; Saito, Mak A; Mercier, Melissa; Whitney, LeAnn P (BMC bioinformatics, 2010)
Keywords: Algorithms; Analysis; Bayes Theorem; Bayesian statistical decision theory; Bias; Bioinformatics; Biological variation; Biomedical and Life Sciences; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Databases, Genetic; DNA replication; Experiments; Gene expression; Gene Expression Profiling - methods; Genetic transcription; Genetic variation; Genomics; Life Sciences; Methods; Microarrays; Oligonucleotide Array Sequence Analysis - methods; Parameter estimation; Research Article; Sequence Analysis, DNA; Sequence Analysis, RNA; Standard deviation; Studies; Transcriptome analysis; Gaussian Approximation; Shrinkage Estimate; Biological Variation; Posterior Expectation; Digital Gene Expression