Exploring the potential association between brominated diphenyl ethers, polychlorinated biphenyls, organochlorine pesticides, perfluorinated compounds, phthalates, and bisphenol a in polycystic ovary syndrome: a case–control study

Background Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association wi...

Full description

Saved in:
Bibliographic Details
Published inBMC endocrine disorders Vol. 14; no. 1; p. 86
Main Authors Vagi, Sara J, Azziz-Baumgartner, Eduardo, Sjödin, Andreas, Calafat, Antonia M, Dumesic, Daniel, Gonzalez, Leonardo, Kato, Kayoko, Silva, Manori J, Ye, Xiaoyun, Azziz, Ricardo
Format Journal Article
LanguageEnglish
Published London BioMed Central 28.10.2014
BioMed Central Ltd
Springer Nature B.V
Subjects
Adolescent
Adult
Benzhydryl Compounds - blood
Bisphenol A
Caprylates - blood
Care and treatment
Case-Control Studies
Chromatography, Gas
Diabetes
Diagnosis
Disease control
Endocrine disruptors
Endocrine Disruptors - adverse effects
Endocrine Disruptors - blood
Endocrinology
Environmental Monitoring
Environmental Pollutants - adverse effects
Environmental Pollutants - blood
Epidemiology of Endocrine Disorders
Female
Fluorocarbons - blood
Halogenated Diphenyl Ethers - blood
Health aspects
Humans
Hydrocarbons, Chlorinated - blood
Mass Spectrometry
Medical centers
Medicine
Medicine & Public Health
Metabolic Diseases
Metabolites
Middle Aged
PCB
Pesticides - blood
Phenols - blood
Phthalic Acids - blood
Pilot Projects
Polychlorinated biphenyls
Polychlorinated Biphenyls - blood
Polycystic ovary syndrome
Polycystic Ovary Syndrome - blood
Polycystic Ovary Syndrome - chemically induced
Polycystic Ovary Syndrome - epidemiology
Prevalence
Research Article
Risk factors
rology
Solid Phase Extraction
Specimen Handling
Stein-Leventhal syndrome
Studies
Type 2 diabetes
United States - epidemiology
United States
Los Angeles California
United States > US
USA, California, Los Angeles
Polycystic Ovary Syndrome
Phthalate
Organochlorine Pesticide
Indoor Dust
PCOS Patient
Online AccessGet full text
ISSN1472-6823
1472-6823
DOI10.1186/1472-6823-14-86

Cover

Abstract Background Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS. Methods Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007–2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine. Results PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GM cases = 4.1 μg/L, GM controls = 2.3 μg/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GM cases = 8.2 μg/L, GM controls = 4.9 μg/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GM cases = 7.5 μg/g creatinine, GM controls = 11.7 μg/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8–6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14–0.25, p < 0.05). Conclusions Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
AbstractList Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS.BACKGROUNDPolycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS.Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007-2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine.METHODSFifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007-2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine.PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GMcases = 4.1 μg/L, GMcontrols = 2.3 μg/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GMcases = 8.2 μg/L, GMcontrols = 4.9 μg/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GMcases = 7.5 μg/g creatinine, GMcontrols = 11.7 μg/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8-6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14-0.25, p < 0.05).RESULTSPCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GMcases = 4.1 μg/L, GMcontrols = 2.3 μg/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GMcases = 8.2 μg/L, GMcontrols = 4.9 μg/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GMcases = 7.5 μg/g creatinine, GMcontrols = 11.7 μg/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8-6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14-0.25, p < 0.05).Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.CONCLUSIONSOur data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS. Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007-2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine. PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GM.sub.cases = 4.1 [mu]g/L, GM.sub.controls = 2.3 [mu]g/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GM.sub.cases = 8.2 [mu]g/L, GM.sub.controls = 4.9 [mu]g/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GM.sub.cases = 7.5 [mu]g/g creatinine, GM.sub.controls = 11.7 [mu]g/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8-6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14-0.25, p < 0.05). Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
Doc number: 86 Abstract Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS. Methods: Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007-2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine. Results: PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GMcases = 4.1 μg/L, GMcontrols = 2.3 μg/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GMcases = 8.2 μg/L, GMcontrols = 4.9 μg/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GMcases = 7.5 μg/g creatinine, GMcontrols = 11.7 μg/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8-6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14-0.25, p < 0.05). Conclusions: Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
Background Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS. Methods Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007–2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine. Results PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GM cases = 4.1 μg/L, GM controls = 2.3 μg/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GM cases = 8.2 μg/L, GM controls = 4.9 μg/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GM cases = 7.5 μg/g creatinine, GM controls = 11.7 μg/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8–6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14–0.25, p < 0.05). Conclusions Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS. Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007-2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine. PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GMcases = 4.1 μg/L, GMcontrols = 2.3 μg/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GMcases = 8.2 μg/L, GMcontrols = 4.9 μg/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GMcases = 7.5 μg/g creatinine, GMcontrols = 11.7 μg/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8-6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14-0.25, p < 0.05). Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endocrine disruptors in animals, little is known about their potential association with PCOS. The objective of this case-control pilot study is to determine whether women with PCOS have higher concentrations of specific environmental contaminants compared to women who have not developed PCOS. Methods: Fifty-two PCOS case-patients (diagnosed using the National Institutes of Health 1990 definition) and 50 controls were recruited in 2007-2008, from an urban academic medical center in Los Angeles, CA. Brominated diphenyl ethers, polychlorinated biphenyls (PCBs), organochlorine pesticides, and perfluorinated compounds (PFCs) were measured in serum, and phthalates metabolites and bisphenol A (BPA) in urine. Results: PCOS case-patients had significantly higher geometric mean (GM) serum concentrations of two PFCs: perfluorooctanoate (PFOA) (GM sub(cases) = 4.1 [mu]g/L, GM sub(controls) = 2.3 [mu]g/L; p = 0.001) and perfluorooctane sulfonate (PFOS) (GM sub(cases) = 8.2 [mu]g/L, GM sub(controls) = 4.9 [mu]g/L; p = 0.01), and lower urinary concentrations of monobenzyl phthalate (mBzP) (GM sub(cases) = 7.5 [mu]g/g creatinine, GM sub(controls) = 11.7 [mu]g/g creatinine; p = 0.02). Logistic regression, controlling for body mass index, age and race, identified an increased likelihood of PCOS in subjects with higher serum concentrations of PFOA and PFOS (adjusted-ORs = 5.8-6.9, p < 0.05), and with lower urine concentrations of mBzP and mono-n-butyl phthalate (mBP) (aORs = 0.14-0.25, p < 0.05). Conclusions: Our data suggest that PCOS case-patients may differ from controls in their environmental contaminant profile. PCOS subjects had higher serum concentrations of two PFCs, PFOA and PFOS, and lower urine concentrations of mBP and mBzP. Future studies are needed to confirm these preliminary findings and determine if these chemicals or their precursors may have a role in the pathogenesis of PCOS.
ArticleNumber 86
Audience Academic
Author Dumesic, Daniel
Azziz-Baumgartner, Eduardo
Ye, Xiaoyun
Vagi, Sara J
Calafat, Antonia M
Sjödin, Andreas
Kato, Kayoko
Gonzalez, Leonardo
Silva, Manori J
Azziz, Ricardo
Author_xml – sequence: 1
  givenname: Sara J
  surname: Vagi
  fullname: Vagi, Sara J
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 2
  givenname: Eduardo
  surname: Azziz-Baumgartner
  fullname: Azziz-Baumgartner, Eduardo
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 3
  givenname: Andreas
  surname: Sjödin
  fullname: Sjödin, Andreas
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 4
  givenname: Antonia M
  surname: Calafat
  fullname: Calafat, Antonia M
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 5
  givenname: Daniel
  surname: Dumesic
  fullname: Dumesic, Daniel
  organization: University of California
– sequence: 6
  givenname: Leonardo
  surname: Gonzalez
  fullname: Gonzalez, Leonardo
  organization: Cedars Sinai Medical Center
– sequence: 7
  givenname: Kayoko
  surname: Kato
  fullname: Kato, Kayoko
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 8
  givenname: Manori J
  surname: Silva
  fullname: Silva, Manori J
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 9
  givenname: Xiaoyun
  surname: Ye
  fullname: Ye, Xiaoyun
  organization: U.S. Centers for Disease Control and Prevention
– sequence: 10
  givenname: Ricardo
  surname: Azziz
  fullname: Azziz, Ricardo
  email: razziz@gru.edu
  organization: University of California, Cedars Sinai Medical Center, Georgia Regents University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/25348326$$D View this record in MEDLINE/PubMed
BookMark eNqNU8tu1DAUjVARfcCaHYrEhgXTOnFiOyyQqqo8pEpsYG157JsZVx472ElLdvwDf8iKz-BmZminFaAqC1v3nnN8fY5zmO354CHLnhfkuCgEOykqXs6YKOmsqGaCPcoObip7O_v97DClS0IKLkryJNsva1oJWrKD7Nf5t86FaP0i75eQd6EH31vlcpVS0Fb1Nvh8Dv01AK4xrKxXPZjc2G4JfnQ5IC2m18h0o16updaA-RaArRAXyodtE8-A1FttDUwsiK0bbkg6rLoweDN1lv1SOaziXvlJL02CASfLrd8cN05CebhScczT6A2OB2-wr1WCn99_6OD7iITUD2Z8mj1ulUvwbLseZV_enX8--zC7-PT-49npxUyzUvQzRQRAww3hTQt6TkStRSNoS8tCG1MWHEvMlGbezAvDCeGc06bVtGg0EC4qepSRje7gOzVeK-dkF-0KR5QFkVNocopFTrHgTgqGlLcbSjfMV2A0JhDVLS0oK-92vF3KRbiSVSk4pQ0KvNoKxPB1QHvlyiYNzikPYUiyYHXFGOM1fQCU1ngrwSbVl_egl2GIHs1boygXhNFb1EI5kNa3AUfUk6g8rWlTo3nVdMXjv6DwM7CymBO0Fut3CC92Pbkx48_LRcDJBqBjSClC-wCb63sMbfv1A8dZrPsPb5to6qb_BOKOD_-g_AY0MSaz
CitedBy_id crossref_primary_10_3390_toxics12020104
crossref_primary_10_1016_j_beem_2021_101552
crossref_primary_10_1016_j_envpol_2019_01_039
crossref_primary_10_1177_25148486231192096
crossref_primary_10_3390_jox14020038
crossref_primary_10_1016_j_tox_2021_153031
crossref_primary_10_1111_joim_13748
crossref_primary_10_1007_s11356_016_7573_5
crossref_primary_10_1289_EHP12783
crossref_primary_10_3389_fendo_2015_00008
crossref_primary_10_1371_journal_pone_0120070
crossref_primary_10_1515_reveh_2022_0187
crossref_primary_10_1515_reveh_2020_0032
crossref_primary_10_3390_toxics12080539
crossref_primary_10_1016_j_fct_2018_06_011
crossref_primary_10_3390_cells12010174
crossref_primary_10_3390_ijerph19031257
crossref_primary_10_1007_s13668_024_00557_5
crossref_primary_10_1016_j_reprotox_2021_06_005
crossref_primary_10_1097_GRF_0000000000000562
crossref_primary_10_1016_j_reprotox_2023_108388
crossref_primary_10_3390_ijms23095176
crossref_primary_10_1007_s00204_020_02834_y
crossref_primary_10_3389_fpubh_2020_553850
crossref_primary_10_1007_s11356_021_15204_7
crossref_primary_10_33920_med_10_2502_07
crossref_primary_10_1007_s40618_022_01885_5
crossref_primary_10_1016_j_envpol_2023_121957
crossref_primary_10_1021_acs_est_4c08701
crossref_primary_10_1093_molehr_gaab003
crossref_primary_10_5468_ogs_2020_63_1_1
crossref_primary_10_1016_j_envpol_2020_115962
crossref_primary_10_1097_MED_0000000000000309
crossref_primary_10_1002_jssc_201901223
crossref_primary_10_1016_j_ddmod_2020_11_008
crossref_primary_10_1016_j_envres_2016_07_011
crossref_primary_10_1016_j_ecoenv_2024_116251
crossref_primary_10_1186_s12958_023_01056_y
crossref_primary_10_3390_ijerph19095608
crossref_primary_10_1080_03007995_2020_1729108
crossref_primary_10_1016_j_ecoenv_2022_113909
crossref_primary_10_1002_ijgo_15349
crossref_primary_10_1007_s11270_018_3796_z
crossref_primary_10_1016_j_envpol_2022_120711
crossref_primary_10_3390_jcm11237227
crossref_primary_10_2903_j_efsa_2023_6857
crossref_primary_10_1080_26896583_2022_2043135
crossref_primary_10_1016_j_envint_2021_106819
crossref_primary_10_3390_ijms21197054
crossref_primary_10_1007_s12403_022_00496_y
crossref_primary_10_1016_j_jsbmb_2022_106195
crossref_primary_10_38053_acmj_955138
crossref_primary_10_1080_09513590_2017_1405931
crossref_primary_10_1016_j_scitotenv_2017_06_137
crossref_primary_10_1016_j_reprotox_2024_108562
crossref_primary_10_33549_physiolres_934521
crossref_primary_10_1177_17455057221117966
crossref_primary_10_1016_j_ando_2017_04_024
crossref_primary_10_1289_EHP11814
crossref_primary_10_1515_reveh_2016_0067
crossref_primary_10_1152_physrev_00023_2015
crossref_primary_10_1016_j_cca_2023_117225
crossref_primary_10_1177_1933719116654992
crossref_primary_10_1515_hmbci_2020_0032
crossref_primary_10_1016_j_envres_2021_112584
crossref_primary_10_3390_ijms21093215
crossref_primary_10_1016_j_envint_2021_106837
crossref_primary_10_1055_s_0043_107242
crossref_primary_10_1016_j_envres_2020_109963
crossref_primary_10_4103_ijmr_IJMR_2077_16
crossref_primary_10_1016_j_etap_2023_104233
crossref_primary_10_1016_j_reprotox_2022_02_006
crossref_primary_10_1016_j_reprotox_2018_06_005
crossref_primary_10_1055_s_0043_104530
crossref_primary_10_1016_j_chemosphere_2021_131495
crossref_primary_10_1016_j_envint_2016_09_013
crossref_primary_10_3390_toxics12090678
crossref_primary_10_1016_j_fertnstert_2016_08_031
crossref_primary_10_1016_j_jsbmb_2024_106641
crossref_primary_10_1530_JME_18_0079
crossref_primary_10_1080_09513590_2019_1630608
crossref_primary_10_3390_biomedicines12061255
crossref_primary_10_1097_MD_0000000000016948
crossref_primary_10_1007_s00103_018_2709_z
crossref_primary_10_1016_S2213_8587_20_30129_7
crossref_primary_10_1007_s11356_021_16489_4
crossref_primary_10_1016_j_fertnstert_2016_05_011
crossref_primary_10_3390_ijerph21121615
crossref_primary_10_4103_pjog_pjog_50_24
crossref_primary_10_1016_j_chemosphere_2023_138877
crossref_primary_10_1093_toxsci_kfac006
crossref_primary_10_3390_jcm12041454
crossref_primary_10_1007_s11356_022_21612_0
crossref_primary_10_1186_s12958_018_0448_5
crossref_primary_10_1055_s_0043_119751
crossref_primary_10_1016_j_envres_2024_118966
crossref_primary_10_1007_s12595_021_00406_1
crossref_primary_10_3390_life13010138
crossref_primary_10_1016_j_scitotenv_2024_175313
crossref_primary_10_1016_j_lfs_2019_116911
crossref_primary_10_1016_j_reprotox_2023_108515
crossref_primary_10_1016_j_yrtph_2021_104862
crossref_primary_10_3390_children6080089
crossref_primary_10_1055_s_0044_1801405
crossref_primary_10_2903_j_efsa_2024_8497
crossref_primary_10_1016_j_fertnstert_2015_01_005
crossref_primary_10_1016_j_ijheh_2018_07_009
crossref_primary_10_1016_j_pestbp_2023_105521
Cites_doi 10.2203/dose-response.003.03.002
10.1080/1047322X.1990.10389587
10.1097/EDE.0b013e31823b5031
10.1210/jc.2003-032046
10.1016/j.reprotox.2011.01.004
10.1210/jc.2010-1658
10.1210/jc.2010-2401
10.1002/jat.1672
10.1016/S0301-2115(01)00441-9
10.1021/ac050390d
10.1289/ehp.0901584
10.1093/humrep/der450
10.1093/humupd/8.3.231
10.1021/ac050671l
10.1016/j.jchromb.2007.10.023
10.1093/humrep/den490
10.1210/jc.2005-0628
10.1111/j.1365-2605.2012.01260.x
10.3109/09513598709023610
10.1146/annurev-physiol-012110-142200
10.1016/j.jsbmb.2004.12.008
10.1210/jc.2003-031122
10.1073/pnas.1207854109
10.1093/toxsci/58.2.339
10.1016/j.mce.2009.02.021
10.1210/jcem.84.11.6148
10.1021/ac030381+
10.1002/sim.4780141908
10.1289/ehp.1205113
10.1507/endocrj.51.165
ContentType Journal Article
Copyright Vagi et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated.
COPYRIGHT 2014 BioMed Central Ltd.
2014 Vagi et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Vagi et al.; licensee BioMed Central Ltd. 2014
Copyright_xml – notice: Vagi et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated.
– notice: COPYRIGHT 2014 BioMed Central Ltd.
– notice: 2014 Vagi et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
– notice: Vagi et al.; licensee BioMed Central Ltd. 2014
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7QP
7TK
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
7X8
7TV
C1K
5PM
ADTOC
UNPAY
DOI 10.1186/1472-6823-14-86
DatabaseName Springer Nature OA Free Journals (WRLC)
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Calcium & Calcified Tissue Abstracts
Neurosciences Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials - QC
ProQuest Central
ProQuest One
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
ProQuest Health & Medical Collection
Medical Database
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
Pollution Abstracts
Environmental Sciences and Pollution Management
PubMed Central (Full Participant titles)
Unpaywall for CDI: Periodical Content
Unpaywall
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
Calcium & Calcified Tissue Abstracts
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
Pollution Abstracts
Environmental Sciences and Pollution Management
DatabaseTitleList MEDLINE - Academic

Publicly Available Content Database

MEDLINE
Pollution Abstracts
Database_xml – sequence: 1
  dbid: C6C
  name: Springer Nature OA Free Journals
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: UNPAY
  name: Unpaywall
  url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/
  sourceTypes: Open Access Repository
– sequence: 5
  dbid: BENPR
  name: Proquest Central
  url: http://www.proquest.com/pqcentral?accountid=15518
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1472-6823
EndPage 86
ExternalDocumentID 10.1186/1472-6823-14-86
PMC4287339
3524617401
A539598346
25348326
10_1186_1472_6823_14_86
Genre Research Support, Non-U.S. Gov't
Journal Article
GeographicLocations United States
Los Angeles California
United States--US
USA, California, Los Angeles
GeographicLocations_xml – name: United States
– name: Los Angeles California
– name: United States--US
– name: USA, California, Los Angeles
GroupedDBID ---
0R~
23N
2WC
4.4
53G
5VS
6J9
6PF
7X7
88E
8FI
8FJ
AAFWJ
AAJSJ
AASML
AAWTL
ABDBF
ABUWG
ACGFO
ACGFS
ACIHN
ACPRK
ACUHS
ADBBV
ADRAZ
ADUKV
AEAQA
AENEX
AFKRA
AFPKN
AHBYD
AHMBA
AHSBF
AHYZX
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AMTXH
AOIJS
BAPOH
BAWUL
BCNDV
BENPR
BFQNJ
BMC
BPHCQ
BVXVI
C6C
CCPQU
CS3
DIK
E3Z
EBD
EBLON
EBS
EJD
ESX
F5P
FYUFA
GROUPED_DOAJ
GX1
H13
HMCUK
HYE
IAO
IHR
INH
INR
IPNFZ
ITC
KQ8
M1P
M48
M~E
O5R
O5S
OK1
OVT
P2P
PGMZT
PHGZM
PHGZT
PIMPY
PJZUB
PPXIY
PQQKQ
PROAC
PSQYO
PUEGO
RBZ
RIG
RNS
ROL
RPM
RSV
SMD
SOJ
TR2
TUS
UKHRP
W2D
WOQ
WOW
XSB
~8M
AAYXX
CITATION
-A0
3V.
ACRMQ
ADINQ
ALIPV
C24
CGR
CUY
CVF
ECM
EIF
NPM
7QP
7TK
7XB
8FK
AZQEC
DWQXO
K9.
PKEHL
PQEST
PQUKI
PRINS
7X8
7TV
C1K
5PM
2VQ
ADTOC
AFFHD
C1A
UNPAY
ID FETCH-LOGICAL-c628t-a08ee97d079fecb085c8983f321cdd217b086d2db9b1d70077739fc319ce07843
IEDL.DBID M48
ISSN 1472-6823
IngestDate Wed Oct 29 11:38:54 EDT 2025
Tue Sep 30 16:59:03 EDT 2025
Tue Oct 07 08:00:08 EDT 2025
Thu Oct 02 10:52:45 EDT 2025
Tue Oct 07 05:13:09 EDT 2025
Mon Oct 20 22:49:31 EDT 2025
Mon Oct 20 17:03:48 EDT 2025
Thu Jan 02 22:21:44 EST 2025
Wed Oct 01 02:40:01 EDT 2025
Thu Apr 24 23:08:34 EDT 2025
Sat Sep 06 07:23:16 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Polycystic Ovary Syndrome
Phthalate
Organochlorine Pesticide
Indoor Dust
PCOS Patient
Language English
License This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
cc-by
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c628t-a08ee97d079fecb085c8983f321cdd217b086d2db9b1d70077739fc319ce07843
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.1186/1472-6823-14-86
PMID 25348326
PQID 1635378063
PQPubID 44656
PageCount 1
ParticipantIDs unpaywall_primary_10_1186_1472_6823_14_86
pubmedcentral_primary_oai_pubmedcentral_nih_gov_4287339
proquest_miscellaneous_1654666753
proquest_miscellaneous_1635007869
proquest_journals_1635378063
gale_infotracmisc_A539598346
gale_infotracacademiconefile_A539598346
pubmed_primary_25348326
crossref_primary_10_1186_1472_6823_14_86
crossref_citationtrail_10_1186_1472_6823_14_86
springer_journals_10_1186_1472_6823_14_86
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2014-10-28
PublicationDateYYYYMMDD 2014-10-28
PublicationDate_xml – month: 10
  year: 2014
  text: 2014-10-28
  day: 28
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle BMC endocrine disorders
PublicationTitleAbbrev BMC Endocr Disord
PublicationTitleAlternate BMC Endocr Disord
PublicationYear 2014
Publisher BioMed Central
BioMed Central Ltd
Springer Nature B.V
Publisher_xml – name: BioMed Central
– name: BioMed Central Ltd
– name: Springer Nature B.V
References Whitworth, Haug, Baird, Becher, Hoppin, Skjaerven, Thomsen, Eggesbo, Travlos, Wilson, Longnecker (CR27) 2012; 23
Fei, McLaughlin, Lipworth, Olsen (CR25) 2009; 24
Donato, Zani (CR30) 2010; 22
Silva, Samandar, Preau, Reidy, Needham, Calafat (CR19) 2007; 860
Knox, Jackson, Javins, Frisbee, Shankar, Ducatman (CR23) 2011; 96
Kuklenyik, Needham, Calafat (CR18) 2005; 77
Casals-Casas, Desvergne (CR13) 2011; 73
Azziz, Marin, Hoq, Badamgarav, Song (CR7) 2005; 90
Kodavanti (CR10) 2005; 3
Hines, White, Stanko, Gibbs-Flournoy, Lau, Fenton (CR14) 2009; 304
Tsutsumi (CR34) 2005; 93
Asuncion, Calvo, San Millan, Sancho, Avila, Escobar-Morreale (CR1) 2000; 85
Hull (CR5) 1987; 1
Parks, Ostby, Lambright, Abbott, Klinefelter, Barlow, Gray (CR12) 2000; 58
Hornung RW (CR21) 1990; 5
Kandaraki, Chatzigeorgiou, Livadas, Palioura, Economou, Koutsilieris, Palimeri, Panidis, Diamanti-Kandarakis (CR33) 2011; 96
Hunt, Lawson, Gieske, Murdoch, Smith, Marre, Hassold, VandeVoort (CR11) 2012; 109
Wild (CR6) 2002; 8
Azziz, Sanchez, Knochenhauer, Moran, Lazenby, Stephens, Taylor, Boots (CR16) 2004; 89
Recio-Vega, Velazco-Rodriguez, Ocampo-Gomez, Hernandez-Gonzalez, Ruiz-Flores, Lopez-Marquez (CR29) 2011; 31
Shelby (CR9) 2008; 22
Cohn, Cirillo, Sholtz, Ferrara, Park, Schwingl (CR28) 2011; 31
Sjodin, Jones, Lapeza, Focant, McGahee, Patterson (CR17) 2004; 76
Ye, Kuklenyik, Needham, Calafat (CR20) 2005; 77
Frederiksen, Sorensen, Mouritsen, Aksglaede, Hagen, Petersen, Skakkebaek, Andersson, Juul (CR32) 2012; 35
Massaad, Entezami, Massade, Benahmed, Olivennes, Barouki, Hamamah (CR8) 2002; 100
Takeuchi, Tsutsumi, Ikezuki, Takai, Taketani (CR35) 2004; 51
Prevention (CR15) 2012
Azziz, Woods, Reyna, Key, Knochenhauer, Yildiz (CR2) 2004; 89
Joensen, Frederiksen, Jensen, Lauritsen, Olesen, Lassen, Andersson, Jorgensen (CR31) 2012; 120
Knochenhauer, Key, Kahsar-Miller, Waggoner, Boots, Azziz (CR4) 1998; 83
(CR36) 2010
Vestergaard, Nielsen, Andersson, Hjollund, Grandjean, Andersen, Jensen (CR26) 2012; 27
Mehta, Patel (CR22) 1995; 14
Diamanti-Kandarakis, Kouli, Bergiele, Filandra, Tsianateli, Spina, Zapanti, Bartzis (CR3) 1999; 84
Melzer, Rice, Depledge, Henley, Galloway (CR24) 2010; 118
CDC (298_CR15) 2012
UN Joensen (298_CR31) 2012; 120
E Diamanti-Kandarakis (298_CR3) 1999; 84
R Azziz (298_CR7) 2005; 90
C Fei (298_CR25) 2009; 24
RA Wild (298_CR6) 2002; 8
SS Knox (298_CR23) 2011; 96
WHO (World Health Organization) (298_CR36) 2010
RL Hornung RW (298_CR21) 1990; 5
R Azziz (298_CR16) 2004; 89
CR Mehta (298_CR22) 1995; 14
X Ye (298_CR20) 2005; 77
F Donato (298_CR30) 2010; 22
C Casals-Casas (298_CR13) 2011; 73
R Recio-Vega (298_CR29) 2011; 31
Z Kuklenyik (298_CR18) 2005; 77
H Frederiksen (298_CR32) 2012; 35
T Takeuchi (298_CR35) 2004; 51
BA Cohn (298_CR28) 2011; 31
M Asuncion (298_CR1) 2000; 85
C Massaad (298_CR8) 2002; 100
LG Parks (298_CR12) 2000; 58
MD Shelby (298_CR9) 2008; 22
O Tsutsumi (298_CR34) 2005; 93
PA Hunt (298_CR11) 2012; 109
ES Knochenhauer (298_CR4) 1998; 83
R Azziz (298_CR2) 2004; 89
E Kandaraki (298_CR33) 2011; 96
A Sjodin (298_CR17) 2004; 76
EP Hines (298_CR14) 2009; 304
S Vestergaard (298_CR26) 2012; 27
MJ Silva (298_CR19) 2007; 860
D Melzer (298_CR24) 2010; 118
MG Hull (298_CR5) 1987; 1
PR Kodavanti (298_CR10) 2005; 3
KW Whitworth (298_CR27) 2012; 23
17997365 - J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Dec 1;860(1):106-12
22246448 - Hum Reprod. 2012 Mar;27(3):873-80
21193545 - J Clin Endocrinol Metab. 2011 Mar;96(3):E480-4
11750951 - Eur J Obstet Gynecol Reprod Biol. 2002 Jan 10;100(2):127-37
21054169 - Annu Rev Physiol. 2011;73:135-62
21411548 - J Clin Endocrinol Metab. 2011 Jun;96(6):1747-53
16159145 - Anal Chem. 2005 Sep 15;77(18):6085-91
15944216 - J Clin Endocrinol Metab. 2005 Aug;90(8):4650-8
19407859 - NTP CERHR MON. 2008 Sep;(22):v, vii-ix, 1-64 passim
10566641 - J Clin Endocrinol Metab. 1999 Nov;84(11):4006-11
16097788 - Anal Chem. 2005 Aug 15;77(16):5407-13
10902790 - J Clin Endocrinol Metab. 2000 Jul;85(7):2434-8
21480306 - J Appl Toxicol. 2011 Apr;31(3):270-8
19176540 - Hum Reprod. 2009 May;24(5):1200-5
22081060 - Epidemiology. 2012 Mar;23(2):257-63
20089479 - Environ Health Perspect. 2010 May;118(5):686-92
15053652 - Anal Chem. 2004 Apr 1;76(7):1921-7
3140583 - Gynecol Endocrinol. 1987 Sep;1(3):235-45
22428786 - Int J Androl. 2012 Jun;35(3):216-26
21296657 - Reprod Toxicol. 2011 Apr;31(3):290-6
22832070 - Environ Health Perspect. 2012 Oct;120(10):1397-403
18648619 - Dose Response. 2006 May 01;3(3):273-305
15181052 - J Clin Endocrinol Metab. 2004 Jun;89(6):2745-9
15118266 - Endocr J. 2004 Apr;51(2):165-9
9745406 - J Clin Endocrinol Metab. 1998 Sep;83(9):3078-82
19433254 - Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105
14764747 - J Clin Endocrinol Metab. 2004 Feb;89(2):453-62
12078834 - Hum Reprod Update. 2002 May-Jun;8(3):231-41
20677670 - Ann Ig. 2010 May-Jun;22(3):185-98
8552893 - Stat Med. 1995 Oct 15;14(19):2143-60
11099646 - Toxicol Sci. 2000 Dec;58(2):339-49
15860277 - J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):325-30
23012422 - Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17525-30
References_xml – volume: 85
  start-page: 2434
  issue: 7
  year: 2000
  end-page: 2438
  ident: CR1
  article-title: A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain
  publication-title: J Clin Endocrinol Metab
– volume: 3
  start-page: 273
  issue: 3
  year: 2005
  end-page: 305
  ident: CR10
  article-title: Neurotoxicity of persistent organic pollutants: possible mode(s) of action and further considerations
  publication-title: Dose Response
  doi: 10.2203/dose-response.003.03.002
– volume: 5
  start-page: 46
  issue: 1
  year: 1990
  end-page: 51
  ident: CR21
  article-title: Estimation of average concentration in the presence of nondetectable values
  publication-title: Appl Occup Environ Hyg
  doi: 10.1080/1047322X.1990.10389587
– volume: 23
  start-page: 257
  issue: 2
  year: 2012
  end-page: 263
  ident: CR27
  article-title: Perfluorinated compounds and subfecundity in pregnant women
  publication-title: Epidemiology
  doi: 10.1097/EDE.0b013e31823b5031
– volume: 22
  start-page: 185
  issue: 3
  year: 2010
  end-page: 198
  ident: CR30
  article-title: [Chronic exposure to organochlorine compounds and health effects in adults: diabetes and thyroid diseases]
  publication-title: Ann Ig
– volume: 89
  start-page: 2745
  issue: 6
  year: 2004
  end-page: 2749
  ident: CR2
  article-title: The prevalence and features of the polycystic ovary syndrome in an unselected population
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2003-032046
– volume: 31
  start-page: 290
  issue: 3
  year: 2011
  end-page: 296
  ident: CR28
  article-title: Polychlorinated biphenyl (PCB) exposure in mothers and time to pregnancy in daughters
  publication-title: Reprod Toxicol
  doi: 10.1016/j.reprotox.2011.01.004
– volume: 96
  start-page: E480
  issue: 3
  year: 2011
  end-page: 484
  ident: CR33
  article-title: Endocrine disruptors and polycystic ovary syndrome (PCOS): elevated serum levels of bisphenol A in women with PCOS
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2010-1658
– volume: 96
  start-page: 1747
  issue: 6
  year: 2011
  end-page: 1753
  ident: CR23
  article-title: Implications of early menopause in women exposed to perfluorocarbons
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2010-2401
– volume: 31
  start-page: 270
  issue: 3
  year: 2011
  end-page: 278
  ident: CR29
  article-title: Serum levels of polychlorinated biphenyls in Mexican women and breast cancer risk
  publication-title: J Appl Toxicol
  doi: 10.1002/jat.1672
– volume: 100
  start-page: 127
  issue: 2
  year: 2002
  end-page: 137
  ident: CR8
  article-title: How can chemical compounds alter human fertility?
  publication-title: Eur J Obstet Gynecol Reprod Biol
  doi: 10.1016/S0301-2115(01)00441-9
– volume: 83
  start-page: 3078
  issue: 9
  year: 1998
  end-page: 3082
  ident: CR4
  article-title: Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study
  publication-title: J Clin Endocrinol Metab
– volume: 77
  start-page: 5407
  issue: 16
  year: 2005
  end-page: 5413
  ident: CR20
  article-title: Automated on-line column-switching HPLC-MS/MS method with peak focusing for the determination of nine environmental phenols in urine
  publication-title: Anal Chem
  doi: 10.1021/ac050390d
– volume: 118
  start-page: 686
  issue: 5
  year: 2010
  end-page: 692
  ident: CR24
  article-title: Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.0901584
– volume: 27
  start-page: 873
  issue: 3
  year: 2012
  end-page: 880
  ident: CR26
  article-title: Association between perfluorinated compounds and time to pregnancy in a prospective cohort of Danish couples attempting to conceive
  publication-title: Hum Reprod
  doi: 10.1093/humrep/der450
– volume: 8
  start-page: 231
  issue: 3
  year: 2002
  end-page: 241
  ident: CR6
  article-title: Long-term health consequences of PCOS
  publication-title: Hum Reprod Update
  doi: 10.1093/humupd/8.3.231
– volume: 77
  start-page: 6085
  issue: 18
  year: 2005
  end-page: 6091
  ident: CR18
  article-title: Measurement of 18 perfluorinated organic acids and amides in human serum using on-line solid-phase extraction
  publication-title: Anal Chem
  doi: 10.1021/ac050671l
– volume: 860
  start-page: 106
  issue: 1
  year: 2007
  end-page: 112
  ident: CR19
  article-title: Quantification of 22 phthalate metabolites in human urine
  publication-title: J Chromatogr B Analyt Technol Biomed Life Sci
  doi: 10.1016/j.jchromb.2007.10.023
– volume: 24
  start-page: 1200
  issue: 5
  year: 2009
  end-page: 1205
  ident: CR25
  article-title: Maternal levels of perfluorinated chemicals and subfecundity
  publication-title: Hum Reprod
  doi: 10.1093/humrep/den490
– volume: 90
  start-page: 4650
  issue: 8
  year: 2005
  end-page: 4658
  ident: CR7
  article-title: Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2005-0628
– volume: 35
  start-page: 216
  issue: 3
  year: 2012
  end-page: 226
  ident: CR32
  article-title: High urinary phthalate concentration associated with delayed pubarche in girls
  publication-title: Int J Androl
  doi: 10.1111/j.1365-2605.2012.01260.x
– year: 2010
  ident: CR36
  publication-title: Joint FAO/WHO Expert Meeting to Review Toxicological and Health Aspects of Bisphenol A: Summary Report including Report of Stakeholders Meeting on Bisphenol A
– volume: 1
  start-page: 235
  issue: 3
  year: 1987
  end-page: 245
  ident: CR5
  article-title: Epidemiology of infertility and polycystic ovarian disease: endocrinological and demographic studies
  publication-title: Gynecol Endocrinol
  doi: 10.3109/09513598709023610
– volume: 73
  start-page: 135
  year: 2011
  end-page: 162
  ident: CR13
  article-title: Endocrine disruptors: from endocrine to metabolic disruption
  publication-title: Annu Rev Physiol
  doi: 10.1146/annurev-physiol-012110-142200
– volume: 93
  start-page: 325
  issue: 2–5
  year: 2005
  end-page: 330
  ident: CR34
  article-title: Assessment of human contamination of estrogenic endocrine-disrupting chemicals and their risk for human reproduction
  publication-title: J Steroid Biochem Mol Biol
  doi: 10.1016/j.jsbmb.2004.12.008
– volume: 22
  start-page: 1
  year: 2008
  end-page: 64 passim
  ident: CR9
  article-title: NTP-CERHR monograph on the potential human reproductive and developmental effects of bisphenol A
  publication-title: Ntp Cerhr Mon
– volume: 89
  start-page: 453
  issue: 2
  year: 2004
  end-page: 462
  ident: CR16
  article-title: Androgen excess in women: experience with over 1000 consecutive patients
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2003-031122
– volume: 109
  start-page: 17525
  issue: 43
  year: 2012
  end-page: 17530
  ident: CR11
  article-title: Bisphenol A alters early oogenesis and follicle formation in the fetal ovary of the rhesus monkey
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1207854109
– volume: 58
  start-page: 339
  issue: 2
  year: 2000
  end-page: 349
  ident: CR12
  article-title: The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/58.2.339
– volume: 304
  start-page: 97
  issue: 1–2
  year: 2009
  end-page: 105
  ident: CR14
  article-title: Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2009.02.021
– volume: 84
  start-page: 4006
  issue: 11
  year: 1999
  end-page: 4011
  ident: CR3
  article-title: A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem.84.11.6148
– volume: 76
  start-page: 1921
  issue: 7
  year: 2004
  end-page: 1927
  ident: CR17
  article-title: Semiautomated high-throughput extraction and cleanup method for the measurement of polybrominated diphenyl ethers, polybrominated biphenyls, and polychlorinated biphenyls in human serum
  publication-title: Anal Chem
  doi: 10.1021/ac030381+
– volume: 14
  start-page: 2143
  issue: 19
  year: 1995
  end-page: 2160
  ident: CR22
  article-title: Exact logistic regression: theory and examples
  publication-title: Stat Med
  doi: 10.1002/sim.4780141908
– volume: 120
  start-page: 1397
  issue: 10
  year: 2012
  end-page: 1403
  ident: CR31
  article-title: Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1205113
– year: 2012
  ident: CR15
  publication-title: Fourth National Report on Human Exposure to Environmental Chemicals, Updated Tables
– volume: 51
  start-page: 165
  issue: 2
  year: 2004
  end-page: 169
  ident: CR35
  article-title: Positive relationship between androgen and the endocrine disruptor, bisphenol A, in normal women and women with ovarian dysfunction
  publication-title: Endocr J
  doi: 10.1507/endocrj.51.165
– volume: 84
  start-page: 4006
  issue: 11
  year: 1999
  ident: 298_CR3
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem.84.11.6148
– volume: 76
  start-page: 1921
  issue: 7
  year: 2004
  ident: 298_CR17
  publication-title: Anal Chem
  doi: 10.1021/ac030381+
– volume: 109
  start-page: 17525
  issue: 43
  year: 2012
  ident: 298_CR11
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1207854109
– volume: 90
  start-page: 4650
  issue: 8
  year: 2005
  ident: 298_CR7
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2005-0628
– volume: 8
  start-page: 231
  issue: 3
  year: 2002
  ident: 298_CR6
  publication-title: Hum Reprod Update
  doi: 10.1093/humupd/8.3.231
– volume: 77
  start-page: 6085
  issue: 18
  year: 2005
  ident: 298_CR18
  publication-title: Anal Chem
  doi: 10.1021/ac050671l
– volume: 31
  start-page: 290
  issue: 3
  year: 2011
  ident: 298_CR28
  publication-title: Reprod Toxicol
  doi: 10.1016/j.reprotox.2011.01.004
– volume: 35
  start-page: 216
  issue: 3
  year: 2012
  ident: 298_CR32
  publication-title: Int J Androl
  doi: 10.1111/j.1365-2605.2012.01260.x
– volume: 89
  start-page: 2745
  issue: 6
  year: 2004
  ident: 298_CR2
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2003-032046
– volume: 22
  start-page: 1
  year: 2008
  ident: 298_CR9
  publication-title: Ntp Cerhr Mon
– volume: 77
  start-page: 5407
  issue: 16
  year: 2005
  ident: 298_CR20
  publication-title: Anal Chem
  doi: 10.1021/ac050390d
– volume: 93
  start-page: 325
  issue: 2–5
  year: 2005
  ident: 298_CR34
  publication-title: J Steroid Biochem Mol Biol
  doi: 10.1016/j.jsbmb.2004.12.008
– volume: 5
  start-page: 46
  issue: 1
  year: 1990
  ident: 298_CR21
  publication-title: Appl Occup Environ Hyg
  doi: 10.1080/1047322X.1990.10389587
– volume: 23
  start-page: 257
  issue: 2
  year: 2012
  ident: 298_CR27
  publication-title: Epidemiology
  doi: 10.1097/EDE.0b013e31823b5031
– volume: 304
  start-page: 97
  issue: 1–2
  year: 2009
  ident: 298_CR14
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2009.02.021
– volume: 83
  start-page: 3078
  issue: 9
  year: 1998
  ident: 298_CR4
  publication-title: J Clin Endocrinol Metab
– volume: 100
  start-page: 127
  issue: 2
  year: 2002
  ident: 298_CR8
  publication-title: Eur J Obstet Gynecol Reprod Biol
  doi: 10.1016/S0301-2115(01)00441-9
– volume: 96
  start-page: 1747
  issue: 6
  year: 2011
  ident: 298_CR23
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2010-2401
– volume: 24
  start-page: 1200
  issue: 5
  year: 2009
  ident: 298_CR25
  publication-title: Hum Reprod
  doi: 10.1093/humrep/den490
– volume: 58
  start-page: 339
  issue: 2
  year: 2000
  ident: 298_CR12
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/58.2.339
– volume: 118
  start-page: 686
  issue: 5
  year: 2010
  ident: 298_CR24
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.0901584
– volume: 89
  start-page: 453
  issue: 2
  year: 2004
  ident: 298_CR16
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2003-031122
– volume-title: Fourth National Report on Human Exposure to Environmental Chemicals, Updated Tables
  year: 2012
  ident: 298_CR15
– volume: 22
  start-page: 185
  issue: 3
  year: 2010
  ident: 298_CR30
  publication-title: Ann Ig
– volume: 14
  start-page: 2143
  issue: 19
  year: 1995
  ident: 298_CR22
  publication-title: Stat Med
  doi: 10.1002/sim.4780141908
– volume: 27
  start-page: 873
  issue: 3
  year: 2012
  ident: 298_CR26
  publication-title: Hum Reprod
  doi: 10.1093/humrep/der450
– volume: 3
  start-page: 273
  issue: 3
  year: 2005
  ident: 298_CR10
  publication-title: Dose Response
  doi: 10.2203/dose-response.003.03.002
– volume: 31
  start-page: 270
  issue: 3
  year: 2011
  ident: 298_CR29
  publication-title: J Appl Toxicol
  doi: 10.1002/jat.1672
– volume: 96
  start-page: E480
  issue: 3
  year: 2011
  ident: 298_CR33
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2010-1658
– volume: 73
  start-page: 135
  year: 2011
  ident: 298_CR13
  publication-title: Annu Rev Physiol
  doi: 10.1146/annurev-physiol-012110-142200
– volume-title: Joint FAO/WHO Expert Meeting to Review Toxicological and Health Aspects of Bisphenol A: Summary Report including Report of Stakeholders Meeting on Bisphenol A
  year: 2010
  ident: 298_CR36
– volume: 120
  start-page: 1397
  issue: 10
  year: 2012
  ident: 298_CR31
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1205113
– volume: 51
  start-page: 165
  issue: 2
  year: 2004
  ident: 298_CR35
  publication-title: Endocr J
  doi: 10.1507/endocrj.51.165
– volume: 1
  start-page: 235
  issue: 3
  year: 1987
  ident: 298_CR5
  publication-title: Gynecol Endocrinol
  doi: 10.3109/09513598709023610
– volume: 860
  start-page: 106
  issue: 1
  year: 2007
  ident: 298_CR19
  publication-title: J Chromatogr B Analyt Technol Biomed Life Sci
  doi: 10.1016/j.jchromb.2007.10.023
– volume: 85
  start-page: 2434
  issue: 7
  year: 2000
  ident: 298_CR1
  publication-title: J Clin Endocrinol Metab
– reference: 22832070 - Environ Health Perspect. 2012 Oct;120(10):1397-403
– reference: 19433254 - Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105
– reference: 16097788 - Anal Chem. 2005 Aug 15;77(16):5407-13
– reference: 8552893 - Stat Med. 1995 Oct 15;14(19):2143-60
– reference: 19407859 - NTP CERHR MON. 2008 Sep;(22):v, vii-ix, 1-64 passim
– reference: 22428786 - Int J Androl. 2012 Jun;35(3):216-26
– reference: 15860277 - J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):325-30
– reference: 19176540 - Hum Reprod. 2009 May;24(5):1200-5
– reference: 22246448 - Hum Reprod. 2012 Mar;27(3):873-80
– reference: 10566641 - J Clin Endocrinol Metab. 1999 Nov;84(11):4006-11
– reference: 11099646 - Toxicol Sci. 2000 Dec;58(2):339-49
– reference: 22081060 - Epidemiology. 2012 Mar;23(2):257-63
– reference: 15118266 - Endocr J. 2004 Apr;51(2):165-9
– reference: 21411548 - J Clin Endocrinol Metab. 2011 Jun;96(6):1747-53
– reference: 17997365 - J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Dec 1;860(1):106-12
– reference: 11750951 - Eur J Obstet Gynecol Reprod Biol. 2002 Jan 10;100(2):127-37
– reference: 16159145 - Anal Chem. 2005 Sep 15;77(18):6085-91
– reference: 14764747 - J Clin Endocrinol Metab. 2004 Feb;89(2):453-62
– reference: 15181052 - J Clin Endocrinol Metab. 2004 Jun;89(6):2745-9
– reference: 15053652 - Anal Chem. 2004 Apr 1;76(7):1921-7
– reference: 20089479 - Environ Health Perspect. 2010 May;118(5):686-92
– reference: 3140583 - Gynecol Endocrinol. 1987 Sep;1(3):235-45
– reference: 21296657 - Reprod Toxicol. 2011 Apr;31(3):290-6
– reference: 15944216 - J Clin Endocrinol Metab. 2005 Aug;90(8):4650-8
– reference: 18648619 - Dose Response. 2006 May 01;3(3):273-305
– reference: 21480306 - J Appl Toxicol. 2011 Apr;31(3):270-8
– reference: 20677670 - Ann Ig. 2010 May-Jun;22(3):185-98
– reference: 21193545 - J Clin Endocrinol Metab. 2011 Mar;96(3):E480-4
– reference: 12078834 - Hum Reprod Update. 2002 May-Jun;8(3):231-41
– reference: 9745406 - J Clin Endocrinol Metab. 1998 Sep;83(9):3078-82
– reference: 10902790 - J Clin Endocrinol Metab. 2000 Jul;85(7):2434-8
– reference: 21054169 - Annu Rev Physiol. 2011;73:135-62
– reference: 23012422 - Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17525-30
SSID ssj0017820
Score 2.383999
Snippet Background Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although...
Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary...
Background Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although...
Doc number: 86 Abstract Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of...
Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although...
SourceID unpaywall
pubmedcentral
proquest
gale
pubmed
crossref
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 86
SubjectTerms Adolescent
Adult
Benzhydryl Compounds - blood
Bisphenol A
Caprylates - blood
Care and treatment
Case-Control Studies
Chromatography, Gas
Diabetes
Diagnosis
Disease control
Endocrine disruptors
Endocrine Disruptors - adverse effects
Endocrine Disruptors - blood
Endocrinology
Environmental Monitoring
Environmental Pollutants - adverse effects
Environmental Pollutants - blood
Epidemiology of Endocrine Disorders
Female
Fluorocarbons - blood
Halogenated Diphenyl Ethers - blood
Health aspects
Humans
Hydrocarbons, Chlorinated - blood
Mass Spectrometry
Medical centers
Medicine
Medicine & Public Health
Metabolic Diseases
Metabolites
Middle Aged
PCB
Pesticides - blood
Phenols - blood
Phthalic Acids - blood
Pilot Projects
Polychlorinated biphenyls
Polychlorinated Biphenyls - blood
Polycystic ovary syndrome
Polycystic Ovary Syndrome - blood
Polycystic Ovary Syndrome - chemically induced
Polycystic Ovary Syndrome - epidemiology
Prevalence
Research Article
Risk factors
rology
Solid Phase Extraction
Specimen Handling
Stein-Leventhal syndrome
Studies
Type 2 diabetes
United States - epidemiology
SummonAdditionalLinks – databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV3ra9swEBddCnt8GHsvWzc0GGyFarUtWZYHY3SjpQwaxlih34xeJgFjZ3ls5B_e37E7R3aTQrtvIXd6WD6dfrJOvyPkbe6kT7XzzJSeM2G1Yyo1nGWRyQDMASbW-B3ybCRPz8W3i_Rih4y6uzAYVtn5xNZRu8biN_JDwA0pzxSsqJ-nvxhmjcLT1S6Fhg6pFdynlmLsFtlNkBlrQHa_HI--_-jPFZAdLhD8xEoexiJLmFQJZ7FgeJ16Y2266qE3lqir4ZP9Geo9cmdZT_Xqj66qjWXq5AG5H_AlPVobxEOy4-tH5PZZOEF_TP72QXcUoB-dNgsMF4IS-vI90RC8Rc2swUgZAKXUTTAYbFXR9oLw_ABKVuA626paBRMUQNRmimqCENpAIg87cR5L-VlZLftCGNCOeZ1QMl6MdYXI94DqGuubY4UN9IxO6nVzK6yINr_1bEU7qoWPILewFLMQdE9bwtwn5Pzk-OfXUxZyPTArE7VgOlLe55mLsrz01gAQtCpXvORJbJ2DfRP8JV3iTG5ilyEJUcbz0oIDsR5QjuBPyaBuav-c0CjWQibCSxtZoU2Sl0Z7FXErI6cUd0PyoXvLhQ1E6JiPoyraDZGSBZpFgWYBvwolh-R9X2C65gC5XvUdmk2B3gHqtDpccoCeIc9WcZTyPIXnEqC5t6UJs9puizvDK4JXmReXc2BI3vRiLImRcrVvlmsdxH0yv0knFbBthZ3qkDxb23L_YEnKBXh56EC2ZeW9AvKRb0vqybjlJcfdN-fQ7n43Hza6ft147fcT5n9j--LmIXlJ7gKYFYgrErVHBovZ0r8CwLgwr4MX-AdmZnAR
  priority: 102
  providerName: ProQuest
– databaseName: Springer Nature OA Free Journals (WRLC)
  dbid: C6C
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1bi9QwFA66gpcH8e7oKhEEXdisbZOmqW_L4rII65ML-1ZyKzNQ2mGms8u8-R_8hz75MzynzdTp4iq-DXMuSdOT5Etz8oWQt7mTPtXOM1N6zoTVjqnUcJZFJgMwB5hY43fI0y_y5Ex8Pk_PA0kSnoXZ3r-PlfwQiyxhUiWcxYIpeZPcghlKdruy8mjYLkDSt8Db8wej0ZRzdeDdmnmuZkUOW6P3yJ1VPdfrS11VW7PP8QNyP8BGeti_54fkhq8fkdunYWP8Mfk55NJRQHR03rSYBQQW-nfz05CTRc2iwQQYwJrUzTDHa13R7tzvch8sKxgRO1edggkKIOougGqCEMpAfg47cx6t_KKsVoMR5qnjdU0ombZTXSGg3ae6Rn9LdNhAzeis7otboyPaXOjFmm4YFD6C3MIM--Pb95BNTzsm3Cfk7PjT16MTFi5xYFYmqmU6Ut7nmYuyvPTWAMKzKle85ElsnYMFEfwlXeJMbmKXIbtQxvPSwshgPcAXwZ-Snbqp_XNCo1gLmQgvbWSFNkleGu1VxK2MnFLcTcjB5j0XNjCc40UbVdGtdJQsMDAKDAz4VSg5Ie8Hg3lP7nG96jsMnAK7Pfi0OpxegJohgVZxmPI8hecSoLk70oTuasfiTegVYbhYFgCKU54pgIsT8mYQoyWmwNW-WfU6COhk_jedVMB6FJagE_Ksj-bhwZKUCxi-oQLZKM4HBSQaH0vq2bQjHMdlNedQ7t6mR2xV_br22hu6zL_a9sV_-H1J7gJkFYgeErVLdtrFyr8CWNia192Q8AtZz2KN
  priority: 102
  providerName: Springer Nature
– databaseName: Unpaywall
  dbid: UNPAY
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1bi9NAFB7WLnh58H6prjKCoAubbppJJhPfirgsQhcfLKxPYW6hxZiUNFXqk__Bf-iTP8Nzkmlsi6sIvoWcc-aSzJz5JjnnG0KeJYbbSBrrqcwyL9TSeCJSzIt9FQOYA0ws8Tvk-IyfTsI359H5Hhmvc2HUR20LU-rKNOSTg80k9LzNccAzFGx1PDdZO-UFPx6GceBxETBvGHqCXyL7PAJo3iP7k7O3o_dNhpHTcPQ-v7HaWpl2_fPGArUbPNn9Qb1GriyLuVx9lnm-sUid3CDFunttbMqHwbJWA_1lh_nxv_X_Jrnu4CwdtePvFtmzxW1yeex-2N8hP7oYPwpIk87LGqOTwEL-GhbUxYpRVZUYmAMYmJoZxp6tctrkIy-OwDIHT90U1SgopwCi5mCq0gmhDuQN0TNj0cpWWb7sjDB-Ho-RQsm0nsocgfYRlQWWt8ACS2gZnRVtdSssiJafZLWia2aHlyDXsPJ___rNRfnThqH3LpmcvH736tRzh0t4mgei9qQvrE1i48dJZrUC5KlFIljGgqE2BjZqcIubwKhEDU2MrEcxSzINHktbgFUhu0d6RVnYB4T6QxnyILRc-zqUKkgyJa3wmea-EYKZPhmsB1aqHfM6HgCSp80OTPAU31-K7w-uUsH75EVnMG9JRy5WfY4jNUV3BGVq6bIqoGVI7JWOIpZE0K8QNA-2NMGN6G3xeqynzo0tUgDrEYsFwNg-edqJ0RJD8wpbLlsdBJo8-ZNOFMI-GbbGfXK_nT5dx4KIhbCsQAPirYnVKSAB-rakmE0bInTc7jMG9R6up-BG0y96XofdHP3bs334D7qPyFWA0iGimkAckF5dLe1jgKu1euKc0E-qGZiT
  priority: 102
  providerName: Unpaywall
Title Exploring the potential association between brominated diphenyl ethers, polychlorinated biphenyls, organochlorine pesticides, perfluorinated compounds, phthalates, and bisphenol a in polycystic ovary syndrome: a case–control study
URI https://link.springer.com/article/10.1186/1472-6823-14-86
https://www.ncbi.nlm.nih.gov/pubmed/25348326
https://www.proquest.com/docview/1635378063
https://www.proquest.com/docview/1635007869
https://www.proquest.com/docview/1654666753
https://pubmed.ncbi.nlm.nih.gov/PMC4287339
https://bmcendocrdisord.biomedcentral.com/counter/pdf/10.1186/1472-6823-14-86
UnpaywallVersion publishedVersion
Volume 14
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVADU
  databaseName: BioMed Central Open Access Free
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: RBZ
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://www.biomedcentral.com/search/
  providerName: BioMedCentral
– providerCode: PRVAFT
  databaseName: Open Access Digital Library
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: KQ8
  dateStart: 20011001
  isFulltext: true
  titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html
  providerName: Colorado Alliance of Research Libraries
– providerCode: PRVAFT
  databaseName: Open Access Digital Library
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: KQ8
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html
  providerName: Colorado Alliance of Research Libraries
– providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: DOA
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVEBS
  databaseName: Academic Search Ultimate
  customDbUrl: https://search.ebscohost.com/login.aspx?authtype=ip,shib&custid=s3936755&profile=ehost&defaultdb=asn
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: ABDBF
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://search.ebscohost.com/direct.asp?db=asn
  providerName: EBSCOhost
– providerCode: PRVBFR
  databaseName: Free Medical Journals
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: DIK
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: http://www.freemedicaljournals.com
  providerName: Flying Publisher
– providerCode: PRVFQY
  databaseName: GFMER Free Medical Journals
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: GX1
  dateStart: 0
  isFulltext: true
  titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php
  providerName: Geneva Foundation for Medical Education and Research
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: M~E
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
– providerCode: PRVAQN
  databaseName: PubMed Central
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: RPM
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/
  providerName: National Library of Medicine
– providerCode: PRVPQU
  databaseName: Health & Medical Collection
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: 7X7
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/healthcomplete
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Proquest Central
  customDbUrl: http://www.proquest.com/pqcentral?accountid=15518
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: BENPR
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://www.proquest.com/central
  providerName: ProQuest
– providerCode: PRVFZP
  databaseName: Scholars Portal Journals: Open Access
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 20250131
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: M48
  dateStart: 20011001
  isFulltext: true
  titleUrlDefault: http://journals.scholarsportal.info
  providerName: Scholars Portal
– providerCode: PRVAVX
  databaseName: HAS SpringerNature Open Access 2022
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: AAJSJ
  dateStart: 20011201
  isFulltext: true
  titleUrlDefault: https://www.springernature.com
  providerName: Springer Nature
– providerCode: PRVAVX
  databaseName: Springer Nature OA Free Journals
  customDbUrl:
  eissn: 1472-6823
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0017820
  issn: 1472-6823
  databaseCode: C6C
  dateStart: 20010112
  isFulltext: true
  titleUrlDefault: http://www.springeropen.com/
  providerName: Springer Nature
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1fa9swEBdrC1v3MPava7YuaDDYCnXnWLIsD8ZIQ0sZJJSyQLYXI0syCRg7y59tedt32Dfc0z7G7hzbSUq7wV5CkruTZPlO-p11viPkZWiE9ZWxTpxY5nCtjCP9mDmBGwcA5gATK3wO2e2J8z7_MPAHq3JA5QROr3XtsJ5Uf5Ief_-yeA8G_64weCnetHjgOUJ6zGlxR4otsgPbVIh1HLp8daSAieHK3D7XCGFSYJ9x0G-xsUNdXafXNqqrQZT1SepdcmeejdXim0rTtc3q7D65V6JM2l6qxQNyy2YPye1ueY7-iPyuQ-8oAEA6zmcYNAQSanW3aBnCReNJjvEyAE2pGWFI2CKlxWvC0yOQTGEBLZoqGOKSAUhFvai8JEIfmM5Dj4xFKTtJ0nkthGHtWN0JKcPZUKWIf4-oyrC9KTaYw8joKFt2t8CGaP5VTRa0SrjwFugaNuRfP36Wwfe0SJz7mPTPTj92zp2y5oOjhSdnjnKltWFg3CBMrI4BEGoZSpYwr6WNAf8J_hLGM3EYt0yAyYgCFiYaFhJtAe1wtke2szyz-4S6LcWFx63QruYq9sIkVla6TAvXSMlMgxxX9znSZUJ0rMuRRoVjJEWEOhKhjsC3SIoGeV0LjJe5QG5mfYWKE6HeQptalS87wMgw31bU9lnow3Vx4DzY4ATr1pvkSvWiyjgiwNA-CySgywZ5UZNREiPmMpvPlzyI_0T4Nx6fg_sKHmuDPFlqc31hlTU0SLCh5zUD5iXfpGSjYZGfHL1wxqDfw8oi1oZ-03wd1ibzr7l9-t8jekZ2Ae9yhB6ePCDbs8ncPgdMOYubZCsYBE2yc3Lau7iEXx3RaRbPZ5rFKgKflyefgd7vXbQ__QGBEYIX
linkProvider Scholars Portal
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1fb9MwELfGJjF4QPynMMBIIJg0szR2EgdpQgM2dWyt0LRJewuO7aiVoqT0D1O_HB-Hz8Fd6mTtpI2nvVW9s-PY57vfxec7Qt7GJrSBMpalmeVMaGWYDFLOIi-NAMwBJlb4HbLbCzun4vtZcLZC_tR3YTCsstaJlaI2pcZv5NuAGwIeSbCon4e_GFaNwtPVuoSGcqUVzE6VYsxd7Di0s3Nw4cY7B99gvd_5_v7eydcOc1UGmA59OWHKk9bGkfGiOLM6BQiiZSx5xv22NgYQO_wVGt-kcdo2Eaa_iXicaRBdbcG-Cg793iJrgosYnL-1L3u9H8fNOQZmo3MJhdoy3G6LyGeh9DlrC4bXtxds4WWLsGASL4drNme2d8n6tBiq2bnK8wWzuH-f3HN4lu7OBfABWbHFQ3K7607sH5G_TZAfBahJh-UEw5OghbqQC-qCxWg6KjEyB0AwNQMMPpvltLqQPN6Cljmo6qqriiF1DECqKlOVjgjPwMQhemAstrKjLJ82jTCAHutIIaU_6asckfYWVQX2N8YOSxgZHRTzx82wI1r-VqMZrVM7fAK6BtPPXJA_rRL0PianN7LqT8hqURb2GaFeW4nQFzbUnhYq9eMsVVZ6XIeekZKbFvlYr3KiXeJ1rP-RJ5UDJsMExSJBsYBfiQxb5EPTYDjPOXI163sUmwS1EfSplbtUASPDvF7JbsDjAN5LAOfGEidoEb1MrgUvcVpsnFzsuRZ505CxJUbmFbacznkQZ4bxdTyBADcZPOMWeTqX5ebF_IALsCowgGhJyhsGzH--TCkG_SoPOnr7nMNzN-v9sDD0q-Zrs9kw_5vb59dPyWuy3jnpHiVHB73DF-QOAGmBmMaXG2R1MpralwBWJ-krpxEo-XnTSugf9Wasnw
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9QwELagSIUeEO8uFDASElRqaBI7jsOtWliVRysOVOot8ivalaJktQ_Q3vgP_ENO_AxmEifsVhTEbbUzntjxePw5Hn8m5HlmhUuUdYEuHAu4UTaQiWZBGuoUwBxgYoXfIU9OxfEZf3-enPvcnHmX7d5tSbZnGpClqVocTm3RDnEpDiOexoGQMQsiHkhxlVzjMLXhBQZDMew3EZAKzrP5_KHQxkR0MRyvzUcXcyX7DdMdcn1ZTdXqqyrLtTlpdIvc9GCSHrW9f5tccdUdsn3it8vvkp99hh0FnEenNTYRHI6q351CfaYW1bMa02IAgVI7wcyvVUmb08DzAyhZQpxsTDUK2iuAqLkWqvZCeAaydpiJdVjKzYpy2RfC7HW8xAkl48VYlQhzD6iq0N4cDdZQMzqp2set0BCtv6jZina8Cq9BbmDe_fHtu8-xpw0_7j1yNnr7eXgc-KsdAiNiuQhUKJ3LUhumWeGMBtxnZCZZweLIWAvLJPhL2NjqTEc2Rc6hlGWFgXhhHIAazu6Traqu3C6hYaS4iLkTJjRc6TgrtHIyZEaEVkpmB-RV18-58bzneP1GmTfrHylydIwcHQN-5VIMyMu-wLSl_Lhc9QU6To7BAGwa5c80QM2QVis_SliWQLs4aO5taMIgNpvizvVyH0TmOUDlhKUSQOSAPOvFWBIT4ypXL1sdhHki-5tOwmGVCgvTAXnQenPfsDhhHII6VCDd8PNeAenHNyXVZNzQkONimzF47n43Itaqftn72u-HzL_e7cP_sPuUbH96M8o_vjv98IjcAEzLEV7Eco9sLWZL9xhw40I_aaLDL51lbcM
linkToUnpaywall http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1bi9NAFB7WLnh58H6prjKCoAubbppJJhPfirgsQhcfLKxPYW6hxZiUNFXqk__Bf-iTP8Nzkmlsi6sIvoWcc-aSzJz5JjnnG0KeJYbbSBrrqcwyL9TSeCJSzIt9FQOYA0ws8Tvk-IyfTsI359H5Hhmvc2HUR20LU-rKNOSTg80k9LzNccAzFGx1PDdZO-UFPx6GceBxETBvGHqCXyL7PAJo3iP7k7O3o_dNhpHTcPQ-v7HaWpl2_fPGArUbPNn9Qb1GriyLuVx9lnm-sUid3CDFunttbMqHwbJWA_1lh_nxv_X_Jrnu4CwdtePvFtmzxW1yeex-2N8hP7oYPwpIk87LGqOTwEL-GhbUxYpRVZUYmAMYmJoZxp6tctrkIy-OwDIHT90U1SgopwCi5mCq0gmhDuQN0TNj0cpWWb7sjDB-Ho-RQsm0nsocgfYRlQWWt8ACS2gZnRVtdSssiJafZLWia2aHlyDXsPJ___rNRfnThqH3LpmcvH736tRzh0t4mgei9qQvrE1i48dJZrUC5KlFIljGgqE2BjZqcIubwKhEDU2MrEcxSzINHktbgFUhu0d6RVnYB4T6QxnyILRc-zqUKkgyJa3wmea-EYKZPhmsB1aqHfM6HgCSp80OTPAU31-K7w-uUsH75EVnMG9JRy5WfY4jNUV3BGVq6bIqoGVI7JWOIpZE0K8QNA-2NMGN6G3xeqynzo0tUgDrEYsFwNg-edqJ0RJD8wpbLlsdBJo8-ZNOFMI-GbbGfXK_nT5dx4KIhbCsQAPirYnVKSAB-rakmE0bInTc7jMG9R6up-BG0y96XofdHP3bs334D7qPyFWA0iGimkAckF5dLe1jgKu1euKc0E-qGZiT
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Exploring+the+potential+association+between+brominated+diphenyl+ethers%2C+polychlorinated+biphenyls%2C+organochlorine+pesticides%2C+perfluorinated+compounds%2C+phthalates%2C+and+bisphenol+a+in+polycystic+ovary+syndrome%3A+a+case%E2%80%93control+study&rft.jtitle=BMC+endocrine+disorders&rft.au=Vagi%2C+Sara+J&rft.au=Azziz-Baumgartner%2C+Eduardo&rft.au=Sj%C3%B6din%2C+Andreas&rft.au=Calafat%2C+Antonia+M&rft.date=2014-10-28&rft.pub=BioMed+Central&rft.eissn=1472-6823&rft.volume=14&rft_id=info:doi/10.1186%2F1472-6823-14-86&rft_id=info%3Apmid%2F25348326&rft.externalDocID=PMC4287339
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1472-6823&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1472-6823&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1472-6823&client=summon