Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism - Zhang, Xiaochu; Lee, Mary R.; Salmeron, Betty Jo; Stein, Dan J.; Hong, L. Elliot; Geng, Xiujuan; Ross, Thomas J.; Li, Nan; Hodgkinson, Colin; Shen, Pei-Hong; Yang, Yihong; Goldman, David; et al. (NeuroImage (Orlando, Fla.), 2013)
Keywords: Addiction; Addictive behaviors; Adult; Anisotropy; Behavior; Biological and medical sciences; Catechol O-Methyltransferase - genetics; Cocaine; COMT; Diffusion Magnetic Resonance Imaging; Dopamine; Drug use; DTI; Female; Fundamental and applied biological sciences. Psychology; Genetics; Genotype; Heroin; Humans; Image Interpretation, Computer-Assisted; Imaging; Male; Nicotine; Polymorphism, Single Nucleotide; Prefrontal Cortex - pathology; Substance-Related Disorders - genetics; Substance-Related Disorders - pathology; Vertebrates: nervous system and sense organs; DTI; Genetics; Addiction; COMT; Imaging; Nicotine; Enzyme; Transferases; White matter; Polymorphism