Accumulation of Gene Polymorphisms Related to Plaque Disruption and Thrombosis Is Associated With Cerebral Infarction in Subjects With Type 2 Diabetes - Katakami, Naoto; Takahara, Mitsuyoshi; Kaneto, Hideaki; Shimizu, Ikki; Ohno, Keizo; Ishibashi, Fukashi; Osonoi, Takeshi; Kashiwagi, Atsunori; Kawamori, Ryuzo; Shimomura, Iichiro; Matsuhisa, Munehide; Yamasaki, Yoshimitsu (Diabetes care, 2010)
Keywords: Adult; Aged; alleles; Biological and medical sciences; blood; Blood clot; blood coagulation factors; Cardiovascular disease; Cerebral Infarction; Cerebral Infarction - epidemiology; Cerebral Infarction - genetics; Cholesterol, HDL; Cholesterol, HDL - blood; clinical examination; coagulation; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 2 - genetics; Diabetes. Impaired glucose tolerance; Diabetic Angiopathies; Diabetic Angiopathies - genetics; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; epidemiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Factor XII; Factor XII - genetics; Female; gelatinase B; Genes; Genetic aspects; genetic polymorphism; Genetic research; genetics; Genotype; Glycated Hemoglobin; Glycated Hemoglobin A - metabolism; Hospitals; Humans; infarction; Japan; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase 9 - genetics; Medical sciences; Metabolic diseases; metabolism; Middle Aged; Miscellaneous; noninsulin-dependent diabetes mellitus; odds ratio; Original Research; pathogenesis; patients; plasminogen activator; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 1 - genetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proteins; Public health. Hygiene; Public health. Hygiene-occupational medicine; regression analysis; risk factors; Thrombosis; Thrombosis - genetics; Triglycerides; Triglycerides - blood; Type 2 diabetes; Von Willebrand factor; von Willebrand Factor - genetics; Japan; Endocrinopathy; Type 2 diabetes; Human; Cerebral infarction; Nervous system diseases; Genetic variability; Nutrition; Cardiovascular disease; Genotype; Metabolic diseases; Thrombosis; Accumulation; Cerebral disorder; Vascular disease; Association; Central nervous system disease; Cerebrovascular disease; Endocrinology; Polymorphism