Effect of low glycemic index food and postprandial exercise on blood glucose level, oxidative stress and antioxidant capacity
Low glycemic index (GI) food and postprandial exercise are non-drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxi...
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          | Published in | Experimental and therapeutic medicine Vol. 9; no. 4; pp. 1201 - 1204 | 
|---|---|
| Main Authors | , , , , , , | 
| Format | Journal Article | 
| Language | English | 
| Published | 
        Greece
          D.A. Spandidos
    
        01.04.2015
     Spandidos Publications Spandidos Publications UK Ltd  | 
| Subjects | |
| Online Access | Get full text | 
| ISSN | 1792-0981 1792-1015 1792-1015  | 
| DOI | 10.3892/etm.2015.2228 | 
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| Abstract | Low glycemic index (GI) food and postprandial exercise are non-drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxidant capacity. A total of 13 healthy subjects were each used in four experiments: i) rice only (control), ii) salad prior to rice (LGI), iii) exercise following rice (EX) and iv) salad prior to rice and exercise following rice (MIX). The blood glucose level, oxidative stress and antioxidant capacity were then measured. At 60 min after the meal, the blood glucose level was observed to be increased in the MIX group compared with that in the LGI group. Furthermore, at 180 min, the antioxidant capacity was found to be reduced in the MIX group compared with those of the LGI and EX groups. These findings suggest that low GI food combined with postprandial exercise does not improve postprandial hyperglycemia. It may be necessary to establish optimal timing and intensity when combining low GI food with postprandial exercise to improve postprandial hyperglycemia. | 
    
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| AbstractList | Low glycemic index (GI) food and postprandial exercise are non-drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxidant capacity. A total of 13 healthy subjects were each used in four experiments: i) rice only (control), ii) salad prior to rice (LGI), iii) exercise following rice (EX) and iv) salad prior to rice and exercise following rice (MIX). The blood glucose level, oxidative stress and antioxidant capacity were then measured. At 60 min after the meal, the blood glucose level was observed to be increased in the MIX group compared with that in the LGI group. Furthermore, at 180 min, the antioxidant capacity was found to be reduced in the MIX group compared with those of the LGI and EX groups. These findings suggest that low GI food combined with postprandial exercise does not improve postprandial hyperglycemia. It may be necessary to establish optimal timing and intensity when combining low GI food with postprandial exercise to improve postprandial hyperglycemia. Low glycemic index (GI) food and postprandial exercise are non-drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxidant capacity. A total of 13 healthy subjects were each used in four experiments: i) rice only (control), ii) salad prior to rice (LGI), iii) exercise following rice (EX) and iv) salad prior to rice and exercise following rice (MIX). The blood glucose level, oxidative stress and antioxidant capacity were then measured. At 60 min after the meal, the blood glucose level was observed to be increased in the MIX group compared with that in the LGI group. Furthermore, at 180 min, the antioxidant capacity was found to be reduced in the MIX group compared with those of the LGI and EX groups. These findings suggest that low GI food combined with postprandial exercise does not improve postprandial hyperglycemia. It may be necessary to establish optimal timing and intensity when combining low GI food with postprandial exercise to improve postprandial hyperglycemia.Low glycemic index (GI) food and postprandial exercise are non-drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxidant capacity. A total of 13 healthy subjects were each used in four experiments: i) rice only (control), ii) salad prior to rice (LGI), iii) exercise following rice (EX) and iv) salad prior to rice and exercise following rice (MIX). The blood glucose level, oxidative stress and antioxidant capacity were then measured. At 60 min after the meal, the blood glucose level was observed to be increased in the MIX group compared with that in the LGI group. Furthermore, at 180 min, the antioxidant capacity was found to be reduced in the MIX group compared with those of the LGI and EX groups. These findings suggest that low GI food combined with postprandial exercise does not improve postprandial hyperglycemia. It may be necessary to establish optimal timing and intensity when combining low GI food with postprandial exercise to improve postprandial hyperglycemia. Low glycemic index (GI) food and postprandial exercise are non-drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxidant capacity. A total of 13 healthy subjects were each used in four experiments: i) rice only (control), ii) salad prior to rice (LGI), iii) exercise following rice (EX) and iv) salad prior to rice and exercise following rice (MIX). The blood glucose level, oxidative stress and antioxidant capacity were then measured. At 60 min after the meal, the blood glucose level was observed to be increased in the MIX group compared with that in the LGI group. Furthermore, at 180 min, the antioxidant capacity was found to be reduced in the MIX group compared with those of the LGI and EX groups. These findings suggest that low GI food combined with postprandial exercise does not improve postprandial hyperglycemia. It may be necessary to establish optimal timing and intensity when combining low GI food with postprandial exercise to improve postprandial hyperglycemia. Key words: glycemic index, blood glucose level, oxidative stress, antioxidant capacity  | 
    
| Audience | Academic | 
    
| Author | TAKANAMI, YOSHIKAZU MURATA, ISAMU KASUYA, NORIAKI OHTA, SHOICHIRO INOUE, YUTAKA KANAMOTO, IKUO KAWAI, YUKARI  | 
    
| AuthorAffiliation | 1 Laboratory of Drug Safety Management, Division of Pharmaceutical Sciences, Josai University, Sakado, Saitama 350-0295, Japan 4 Louis Pasteur Center for Medical Research, Kyoto 606-8225, Japan 2 Department of Urology, Kan-Etsu Hospital, Tsurugashima, Saitama 350-2213, Japan 3 Department of Food Science, Otsuma Women’s University, Tokyo 102-8357, Japan  | 
    
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25780409$$D View this record in MEDLINE/PubMed | 
    
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| Keywords | glycemic index blood glucose level antioxidant capacity oxidative stress  | 
    
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| References_xml | – volume: 92 start-page: 367 year: 2004 end-page: 381 ident: b10-etm-09-04-1201 article-title: Meta-analysis of the health effects of using the glycaemic index in meal-planning publication-title: Br J Nutr doi: 10.1079/BJN20041203 – volume: 108 start-page: 635 year: 2001 end-page: 636 ident: b8-etm-09-04-1201 article-title: Acute hyperglycemia induces an oxidative stress in healthy subjects publication-title: J Clin Invest doi: 10.1172/JCI13727 – volume: 106 start-page: 2067 year: 2002 end-page: 2072 ident: b7-etm-09-04-1201 article-title: Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress publication-title: Circulation doi: 10.1161/01.CIR.0000034509.14906.AE – volume: 30 start-page: 146 year: 1998 end-page: 149 ident: b5-etm-09-04-1201 article-title: Hyperglycemia-induced circulating ICAM-1 increase in diabetes mellitus: the possible role of oxidative stress publication-title: Horm Metab Res doi: 10.1055/s-2007-978854 – volume: 29 start-page: 775 year: 2006 end-page: 780 ident: b13-etm-09-04-1201 article-title: Cereal fiber improves whole-body insulin sensitivity in overweight and obese women publication-title: Diabetes Care doi: 10.2337/diacare.29.04.06.dc05-2374 – volume: 71 start-page: 1123 year: 2000 end-page: 1128 ident: b12-etm-09-04-1201 article-title: Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects publication-title: Am J Clin Nutr – volume: 21 start-page: 1529 year: 1998 end-page: 1533 ident: b19-etm-09-04-1201 article-title: Meal-generated oxidative stress in type 2 diabetic patients publication-title: Diabetes Care doi: 10.2337/diacare.21.9.1529 – volume: 21 start-page: 1861 year: 1998 end-page: 1969 ident: b3-etm-09-04-1201 article-title: Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis publication-title: Diabetes Care doi: 10.2337/diacare.21.11.1861 – volume: 40 start-page: 447 year: 1997 end-page: 453 ident: b16-etm-09-04-1201 article-title: The effect of moderate exercise on postprandial glucose homeostasis in NIDDM patients publication-title: Diabetologia doi: 10.1007/s001250050699 – volume: 14 start-page: 3380 year: 2009 end-page: 3400 ident: b17-etm-09-04-1201 article-title: Targeting the AMPK pathway for the treatment of Type 2 diabetes publication-title: Front Biosci (Landmark Ed) doi: 10.2741/3460 – volume: 85 start-page: 2860 year: 2000 end-page: 2864 ident: b18-etm-09-04-1201 article-title: Impact of time interval from the last meal on glucose response to exercise in subjects with type 2 diabetes publication-title: J Clin Endocrinol Metab – volume: 332 start-page: 73 year: 2006 end-page: 78 ident: b1-etm-09-04-1201 article-title: Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies publication-title: BMJ doi: 10.1136/bmj.38678.389583.7C – volume: 97 start-page: 1695 year: 1998 end-page: 1701 ident: b9-etm-09-04-1201 article-title: Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo publication-title: Circulation doi: 10.1161/01.CIR.97.17.1695 – volume: 39 start-page: 1145 year: 2002 end-page: 50 ident: b6-etm-09-04-1201 article-title: Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(02)01741-2 – volume: 26 start-page: 434 year: 2007 end-page: 444 ident: b14-etm-09-04-1201 article-title: A MUFA-rich diet improves posprandial glucose, lipid and GLP-1 responses in insulin-resistant subjects publication-title: J Am Coll Nutr doi: 10.1080/07315724.2007.10719633 – volume: 95 start-page: 1238 year: 2012 end-page: 1244 ident: b20-etm-09-04-1201 article-title: Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans publication-title: Am J Clin Nutr doi: 10.3945/ajcn.111.029207 – volume: 161 start-page: 397 year: 2001 end-page: 405 ident: b4-etm-09-04-1201 article-title: Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria publication-title: Arch Intern Med doi: 10.1001/archinte.161.3.397 – volume: 59 start-page: 983 year: 2005 end-page: 988 ident: b15-etm-09-04-1201 article-title: Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects publication-title: Eur J Clin Nutr doi: 10.1038/sj.ejcn.1602197 – volume: 67 start-page: 187 year: 2005 end-page: 197 ident: b21-etm-09-04-1201 article-title: Molecular mechanisms of vascular adaptations to exercise: Physical activity as an effective antioxidant therapy? publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.04.032 – volume: 339 start-page: 229 year: 1998 end-page: 234 ident: b2-etm-09-04-1201 article-title: Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction publication-title: N Engl J Med doi: 10.1056/NEJM199807233390404 – volume: 53 start-page: 96 year: 2010 end-page: 101 ident: b11-etm-09-04-1201 article-title: Effect of differences in low glycemic index food intake sequence on plasma glucose profile publication-title: J Jpn Diabetes Soc – volume: 108 start-page: 635 year: 2001 ident: key20180108125752_b8-etm-09-04-1201 article-title: Acute hyperglycemia induces an oxidative stress in healthy subjects publication-title: J Clin Invest doi: 10.1172/JCI13727 – volume: 14 start-page: 3380 year: 2009 ident: key20180108125752_b17-etm-09-04-1201 article-title: Targeting the AMPK pathway for the treatment of Type 2 diabetes publication-title: Front Biosci (Landmark Ed) doi: 10.2741/3460 – volume: 53 start-page: 96 year: 2010 ident: key20180108125752_b11-etm-09-04-1201 article-title: Effect of differences in low glycemic index food intake sequence on plasma glucose profile publication-title: J Jpn Diabetes Soc – volume: 85 start-page: 2860 year: 2000 ident: key20180108125752_b18-etm-09-04-1201 article-title: Impact of time interval from the last meal on glucose response to exercise in subjects with type 2 diabetes publication-title: J Clin Endocrinol Metab – volume: 106 start-page: 2067 year: 2002 ident: key20180108125752_b7-etm-09-04-1201 article-title: Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress publication-title: Circulation doi: 10.1161/01.CIR.0000034509.14906.AE – volume: 30 start-page: 146 year: 1998 ident: key20180108125752_b5-etm-09-04-1201 article-title: Hyperglycemia-induced circulating ICAM-1 increase in diabetes mellitus: the possible role of oxidative stress publication-title: Horm Metab Res doi: 10.1055/s-2007-978854 – volume: 40 start-page: 447 year: 1997 ident: key20180108125752_b16-etm-09-04-1201 article-title: The effect of moderate exercise on postprandial glucose homeostasis in NIDDM patients publication-title: Diabetologia doi: 10.1007/s001250050699 – volume: 67 start-page: 187 year: 2005 ident: key20180108125752_b21-etm-09-04-1201 article-title: Molecular mechanisms of vascular adaptations to exercise: Physical activity as an effective antioxidant therapy? 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| SubjectTerms | antioxidant capacity Antioxidants blood glucose level Blood sugar Diabetes Exercise Food Glucose Glycemic index Health aspects Hyperglycemia Insulin Meals Medical research Medicine, Experimental Musculoskeletal system Olive oil Oxidative stress Physiological aspects Plasma Rice Salads Vinegar  | 
    
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