Genetic and Evolutionary Analyses of the Human Bone Morphogenetic Protein Receptor 2 (BMPR2) in the Pathophysiology of Obesity - Schleinitz, Dorit; Klöting, Nora; Böttcher, Yvonne; Wolf, Sara; Dietrich, Kerstin; Tönjes, Anke; Breitfeld, Jana; Enigk, Beate; Halbritter, Jan; Körner, Antje; Schön, Michael R.; Jenkner, Jost; et al. (PloS one, 2011)
Keywords: Adipocytes; Adipogenesis; Adipose tissue; Adipose Tissue - metabolism; Adipose Tissue - pathology; Adult; Aged; Analysis; Bioinformatics; Biological evolution; Biology; Body mass; Body weight; Bone morphogenetic protein receptor type II; Bone morphogenetic protein receptors; Bone Morphogenetic Protein Receptors, Type II - analysis; Bone Morphogenetic Protein Receptors, Type II - genetics; Bone Morphogenetic Protein Receptors, Type II - metabolism; Bone Morphogenetic Protein Receptors, Type II - physiology; Bone morphogenetic proteins; Bones; Cardiovascular disease; Cohort Studies; Coronary vessels; Data processing; Deoxyribonucleic acid; Diabetes; Diabetes Mellitus, Type 2 - ethnology; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - pathology; DNA; European Continental Ancestry Group - ethnology; European Continental Ancestry Group - genetics; Evolution; Evolution, Molecular; Evolutionary design method; Fasting; Fats; Female; Gene expression; Genes; Genetic aspects; Genetic Association Studies; Genetics; Genomes; Genotypes; Germany - ethnology; Glucose - metabolism; Haplotypes; Human populations; Humans; Hypertension; Hypotheses; Insulin; Insulin Resistance - genetics; Insulin Resistance - physiology; Interdisciplinary aspects; Kinases; Loci; Male; Measurement; Medicine; Messenger RNA; Middle Aged; Nucleotide sequence; Obesity; Obesity - ethnology; Obesity - genetics; Obesity - metabolism; Obesity - pathology; Overweight; Phylogenetics; Polymorphism, Single Nucleotide; Population; Populations; Proteins; Replication; Research design; Rodents; Signaling; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Statistical analysis; Statistical methods; Stem cells; Studies; Type 2 diabetes; Vertebrates; Germany