Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization - Tappu, Rewati; Haas, Jan; Lehmann, David H.; Sedaghat-Hamedani, Farbod; Kayvanpour, Elham; Keller, Andreas; Katus, Hugo A.; Frey, Norbert; Meder, Benjamin (PloS one, 2022)
Keywords: Algorithms; Analysis; Biological activity; Biology and life sciences; Biopsy; Cardiomyopathy; Cardiomyopathy, Dilated; Cardiovascular disease; Clustering; Computer and Information Sciences; Computer-aided medical diagnosis; Congestive heart failure; Correlation; Correlation coefficient; Correlation coefficients; CpG islands; Data analysis; Datasets; Decomposition; Deoxyribonucleic acid; Diagnosis; Dilated cardiomyopathy; DNA; DNA methylation; DNA Methylation - genetics; Extracellular matrix; Factorization; Gene expression; Gene sequencing; Genetic aspects; Genomes; Heart; High-Throughput Nucleotide Sequencing; Human tissues; Humans; Immune response; Leucine; Medicine and Health Sciences; Methods; Methylation; Network analysis; Nucleic acids; Pathogenesis; Patients; Phospholipids; Physical Sciences; Research and Analysis Methods; RNA sequencing; Sarcomeres - metabolism; Tissues; Transcriptomes; Tropomyosin; Variables; Germany