Droplet microfluidic technology for single-cell high-throughput screening - Brouzes, Eric; Medkova, Martina; Savenelli, Neal; Marran, Dave; Twardowski, Mariusz; Hutchison, J. Brian; Rothberg, Jonathan M; Link, Darren R; Perrimon, Norbert; Samuels, Michael L (Proceedings of the National Academy of Sciences - PNAS, 2009)
Keywords: Biological Sciences; Biomedical technology; Cell growth; Cell Survival - drug effects; cell viability; Cells; Cytotoxicity; droplets; Drug Evaluation, Preclinical - methods; drugs; Dyes; Emulsions; Encapsulation; Fluorescent Dyes - chemistry; Humans; Libraries; Mammals; Microfluidic Analytical Techniques - methods; Microfluidics - instrumentation; Microfluidics - methods; Mitomycin - chemistry; Mitomycin - pharmacology; Nozzles; oils; Physical Sciences; Preclinical drug evaluation; Reagents; Reproducibility of Results; screening; Time Factors; Toxicity; U937 Cells; Validation studies; Viability