An insertion variant of MGMT disrupts a STAT1 binding site and confers susceptibility to glioma - Huang, Liming; Xu, Wenshen; Yan, Danfang; Shi, Xi; You, Xin; Xu, Jiaqi; You, Pingping; Ke, Yuanyuan; Dai, Lian (Cancer cell international, 2021)
Keywords: Alkylation; Alleles; Binding sites; Biomedical and Life Sciences; Biomedicine; Biotechnology; Brain research; Cancer; Cancer Research; Carcinogenesis; Cell Biology; Deoxyribonucleic acid; DNA; DNA damage; DNA methylation; DNA methyltransferase; DNA repair; Epigenetics; Expression quantitative trait locus; Gene expression; Genetic diversity; Genomes; Genotype & phenotype; Genotypes; Glioma; Hospitals; Insertion; Medical prognosis; Methylguanine; MGMT; Nervous system; O6-methylguanine-DNA methyltransferase; Patients; Population studies; Primary Research; Proteins; Quantitative trait loci; Reporter gene; siRNA; STAT1; Stat1 protein; Susceptibility; Tumors; United States--US; China; Glioma; Susceptibility; Expression quantitative trait locus