Is the C-reactive protein/albumin ratio a prognostic and predictive factor in sudden hearing loss?
Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions....
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Published in | Brazilian journal of otorhinolaryngology Vol. 86; no. 2; pp. 180 - 184 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Brazil
Elsevier Editora Ltda
01.03.2020
Elsevier Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial |
Subjects | |
Online Access | Get full text |
ISSN | 1808-8694 1808-8686 1808-8686 |
DOI | 10.1016/j.bjorl.2018.10.007 |
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Abstract | Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions.
The aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio.
A retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests.
The patients included 16 females and 24 males with a mean age of 44.1±14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2±13.8 years. The mean C-reactive protein/albumin ratio was 0.95±0.47 in the patient group and 0.74±0.13 in the control group. The difference was statistically significant (p=0.009). The mean C-reactive protein/albumin ratio was 0.79±0.12 in the response to treatment group and 1.27±0.72 in the non-response group, with no significant difference determined between the groups (p=0.418). The mean neutrophil/lymphocyte ratio was 3.52±3.00 in the response to treatment group and 4.90±4.60 in the non-response group, with no statistically significant difference determined between the groups (p=0.261).
C-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant.
A perda auditiva neurossensorial súbita ou surdez súbita é uma emergência otológica significativa. Estudos anteriores revelaram uma coexistência dessa condição com inflamação crônica. A importância preditiva dos valores da relação proteína C-reativa/albumina como fator prognóstico tem sido demonstrada em várias condições inflamatórias e tumorais.
O objetivo deste estudo foi determinar se a relação proteína C-reativa/albumina na perda auditiva neurossensorial súbita pode ser usada para fins prognósticos e se existe uma associação entre as relações neutrófilo/linfócito e proteína C-reativa/albumina.
Foram avaliados retrospectivamente 40 pacientes com diagnóstico de perda auditiva neurossensorial súbita idiopática e um grupo controle de 45 indivíduos saudáveis. As médias de tons puros de todos os pacientes foram determinadas na primeira consulta e repetidas 3 meses após o tratamento. Os pacientes foram separados em 2 grupos de acordo com a resposta ao tratamento. As relações neutrófilo/linfócito e proteína C-reativa/albumina foram calculadas a partir de testes laboratoriais.
Os pacientes incluíam 16 mulheres e 24 homens, com média de 44,1±14,2 anos, e o grupo controle por 23 mulheres e 22 homens, com média de 42,2±13,8 anos. A média da relação proteína C-reativa/albumina foi de 0,95±0,47 no grupo de pacientes e de 0,74±0,13 no grupo controle e a diferença foi estatisticamente significante (p=0,009). A média da relação proteína C-reativa/albumina foi de 0,79±0,12 do grupo com resposta ao tratamento e de 1,27±0,72 no grupo sem resposta, sem diferença significante entre os grupos (p=0,418). A média da relação neutrófilo/linfócito foi de 3,52±3,00 no grupo com resposta ao tratamento e de 4,90±4,60 no grupo sem resposta, sem diferença estatisticamente significativa entre os grupos (p=0,261).
A relação proteína C-reativa/albumina foi significantemente maior nos pacientes com perda auditiva neurossensorial súbita do que no grupo controle. No entanto, embora a relação proteína C-reativa/albumina tenha sido menor nos pacientes com perda auditiva neurossensorial súbita que responderam ao tratamento em comparação a aqueles que não apresentaram resposta, a diferença entre os dois grupos não foi estatisticamente significante. |
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AbstractList | Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions.
The aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio.
A retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests.
The patients included 16 females and 24 males with a mean age of 44.1±14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2±13.8 years. The mean C-reactive protein/albumin ratio was 0.95±0.47 in the patient group and 0.74±0.13 in the control group. The difference was statistically significant (p=0.009). The mean C-reactive protein/albumin ratio was 0.79±0.12 in the response to treatment group and 1.27±0.72 in the non-response group, with no significant difference determined between the groups (p=0.418). The mean neutrophil/lymphocyte ratio was 3.52±3.00 in the response to treatment group and 4.90±4.60 in the non-response group, with no statistically significant difference determined between the groups (p=0.261).
C-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant. Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions.INTRODUCTIONSudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions.The aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio.OBJECTIVESThe aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio.A retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests.METHODSA retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests.The patients included 16 females and 24 males with a mean age of 44.1±14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2±13.8 years. The mean C-reactive protein/albumin ratio was 0.95±0.47 in the patient group and 0.74±0.13 in the control group. The difference was statistically significant (p=0.009). The mean C-reactive protein/albumin ratio was 0.79±0.12 in the response to treatment group and 1.27±0.72 in the non-response group, with no significant difference determined between the groups (p=0.418). The mean neutrophil/lymphocyte ratio was 3.52±3.00 in the response to treatment group and 4.90±4.60 in the non-response group, with no statistically significant difference determined between the groups (p=0.261).RESULTSThe patients included 16 females and 24 males with a mean age of 44.1±14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2±13.8 years. The mean C-reactive protein/albumin ratio was 0.95±0.47 in the patient group and 0.74±0.13 in the control group. The difference was statistically significant (p=0.009). The mean C-reactive protein/albumin ratio was 0.79±0.12 in the response to treatment group and 1.27±0.72 in the non-response group, with no significant difference determined between the groups (p=0.418). The mean neutrophil/lymphocyte ratio was 3.52±3.00 in the response to treatment group and 4.90±4.60 in the non-response group, with no statistically significant difference determined between the groups (p=0.261).C-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant.CONCLUSIONC-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant. Introduction: Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions. Objectives: The aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio. Methods: A retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests. Results: The patients included 16 females and 24 males with a mean age of 44.1 ± 14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2 ± 13.8 years. The mean C-reactive protein/albumin ratio was 0.95 ± 0.47 in the patient group and 0.74 ± 0.13 in the control group. The difference was statistically significant (p = 0.009). The mean C-reactive protein/albumin ratio was 0.79 ± 0.12 in the response to treatment group and 1.27 ± 0.72 in the non-response group, with no significant difference determined between the groups (p = 0.418). The mean neutrophil/lymphocyte ratio was 3.52 ± 3.00 in the response to treatment group and 4.90 ± 4.60 in the non-response group, with no statistically significant difference determined between the groups (p = 0.261). Conclusion: C-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant. Resumo: Introdução: A perda auditiva neurossensorial súbita ou surdez súbita é uma emergência otológica significativa. Estudos anteriores revelaram uma coexistência dessa condição com inflamação crônica. A importância preditiva dos valores da relação proteína C-reativa/albumina como fator prognóstico tem sido demonstrada em várias condições inflamatórias e tumorais. Objetivos: O objetivo deste estudo foi determinar se a relação proteína C-reativa/albumina na perda auditiva neurossensorial súbita pode ser usada para fins prognósticos e se existe uma associação entre as relações neutrófilo/linfócito e proteína C-reativa/albumina. Método: Foram avaliados retrospectivamente 40 pacientes com diagnóstico de perda auditiva neurossensorial súbita idiopática e um grupo controle de 45 indivíduos saudáveis. As médias de tons puros de todos os pacientes foram determinadas na primeira consulta e repetidas 3 meses após o tratamento. Os pacientes foram separados em 2 grupos de acordo com a resposta ao tratamento. As relações neutrófilo/linfócito e proteína C-reativa/albumina foram calculadas a partir de testes laboratoriais. Resultados: Os pacientes incluíam 16 mulheres e 24 homens, com média de 44,1 ± 14,2 anos, e o grupo controle por 23 mulheres e 22 homens, com média de 42,2 ± 13,8 anos. A média da relação proteína C-reativa/albumina foi de 0,95 ± 0,47 no grupo de pacientes e de 0,74 ± 0,13 no grupo controle e a diferença foi estatisticamente significante (p = 0,009). A média da relação proteína C-reativa/albumina foi de 0,79 ± 0,12 do grupo com resposta ao tratamento e de 1,27 ± 0,72 no grupo sem resposta, sem diferença significante entre os grupos (p = 0,418). A média da relação neutrófilo/linfócito foi de 3,52 ± 3,00 no grupo com resposta ao tratamento e de 4,90 ± 4,60 no grupo sem resposta, sem diferença estatisticamente significativa entre os grupos (p = 0,261). Conclusão: A relação proteína C-reativa/albumina foi significantemente maior nos pacientes com perda auditiva neurossensorial súbita do que no grupo controle. No entanto, embora a relação proteína C-reativa/albumina tenha sido menor nos pacientes com perda auditiva neurossensorial súbita que responderam ao tratamento em comparação a aqueles que não apresentaram resposta, a diferença entre os dois grupos não foi estatisticamente significante. Keywords: Sudden hearing loss, C-reactive protein, Albumin, Chronic inflammation, Palavras-chave: Perda auditiva súbita, Proteína C-reativa, Albumina, Inflamação crônica Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions. The aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio. A retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests. The patients included 16 females and 24 males with a mean age of 44.1±14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2±13.8 years. The mean C-reactive protein/albumin ratio was 0.95±0.47 in the patient group and 0.74±0.13 in the control group. The difference was statistically significant (p=0.009). The mean C-reactive protein/albumin ratio was 0.79±0.12 in the response to treatment group and 1.27±0.72 in the non-response group, with no significant difference determined between the groups (p=0.418). The mean neutrophil/lymphocyte ratio was 3.52±3.00 in the response to treatment group and 4.90±4.60 in the non-response group, with no statistically significant difference determined between the groups (p=0.261). C-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant. A perda auditiva neurossensorial súbita ou surdez súbita é uma emergência otológica significativa. Estudos anteriores revelaram uma coexistência dessa condição com inflamação crônica. A importância preditiva dos valores da relação proteína C-reativa/albumina como fator prognóstico tem sido demonstrada em várias condições inflamatórias e tumorais. O objetivo deste estudo foi determinar se a relação proteína C-reativa/albumina na perda auditiva neurossensorial súbita pode ser usada para fins prognósticos e se existe uma associação entre as relações neutrófilo/linfócito e proteína C-reativa/albumina. Foram avaliados retrospectivamente 40 pacientes com diagnóstico de perda auditiva neurossensorial súbita idiopática e um grupo controle de 45 indivíduos saudáveis. As médias de tons puros de todos os pacientes foram determinadas na primeira consulta e repetidas 3 meses após o tratamento. Os pacientes foram separados em 2 grupos de acordo com a resposta ao tratamento. As relações neutrófilo/linfócito e proteína C-reativa/albumina foram calculadas a partir de testes laboratoriais. Os pacientes incluíam 16 mulheres e 24 homens, com média de 44,1±14,2 anos, e o grupo controle por 23 mulheres e 22 homens, com média de 42,2±13,8 anos. A média da relação proteína C-reativa/albumina foi de 0,95±0,47 no grupo de pacientes e de 0,74±0,13 no grupo controle e a diferença foi estatisticamente significante (p=0,009). A média da relação proteína C-reativa/albumina foi de 0,79±0,12 do grupo com resposta ao tratamento e de 1,27±0,72 no grupo sem resposta, sem diferença significante entre os grupos (p=0,418). A média da relação neutrófilo/linfócito foi de 3,52±3,00 no grupo com resposta ao tratamento e de 4,90±4,60 no grupo sem resposta, sem diferença estatisticamente significativa entre os grupos (p=0,261). A relação proteína C-reativa/albumina foi significantemente maior nos pacientes com perda auditiva neurossensorial súbita do que no grupo controle. No entanto, embora a relação proteína C-reativa/albumina tenha sido menor nos pacientes com perda auditiva neurossensorial súbita que responderam ao tratamento em comparação a aqueles que não apresentaram resposta, a diferença entre os dois grupos não foi estatisticamente significante. Abstract Introduction: Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The predictive importance of C-reactive protein/albumin values as a prognostic factor has been shown in various inflammatory and tumoral conditions. Objectives: The aim of this study was to determine whether the C-reactive protein/albumin ratio in sudden hearing loss can be used for prognostic purposes and whether there is a relationship between the neutrophil/lymphocyte ratio and the C-reactive protein/albumin ratio. Methods: A retrospective examination was made of 40 patients diagnosed with idiopathic sudden hearing loss and a control group of 45 healthy subjects. The pure tone averages of all the patients were determined on first presentation and repeated at 3 months after the treatment. The patients were separated into 2 groups according to the response to treatment. The neutrophil/lynphocyte ratio and the C-reactive protein/albumin ratios were calculated from the laboratory tests. Results: The patients included 16 females and 24 males with a mean age of 44.1 ± 14.2 years and the control group was composed of 23 females and 22 males with a mean age of 42.2 ± 13.8 years. The mean C-reactive protein/albumin ratio was 0.95 ± 0.47 in the patient group and 0.74 ± 0.13 in the control group. The difference was statistically significant (p = 0.009). The mean C-reactive protein/albumin ratio was 0.79 ± 0.12 in the response to treatment group and 1.27 ± 0.72 in the non-response group, with no significant difference determined between the groups (p = 0.418). The mean neutrophil/lymphocyte ratio was 3.52 ± 3.00 in the response to treatment group and 4.90 ± 4.60 in the non-response group, with no statistically significant difference determined between the groups (p = 0.261). Conclusion: C-reactive/albumin ratio was significantly higher in patients with sudden hearing loss than in the control group. Although C-reactive protein/albumin ratio was found to be lower in sudden hearing loss patients who responded to treatment compared to those who did not, the difference between two groups was not statistically significant. |
Author | Alataş, Necat Akın Öçal, Fatma Ceyda Güllüev, Mustafa Öçal, Ramazan |
AuthorAffiliation | Health Sciences University |
AuthorAffiliation_xml | – name: Health Sciences University |
Author_xml | – sequence: 1 givenname: Ramazan orcidid: 0000-0002-9087-4806 surname: Öçal fullname: Öçal, Ramazan email: drramazanocal@gmail.com organization: Health Sciences University, Ankara Training and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Ankara, Turkey – sequence: 2 givenname: Fatma Ceyda surname: Akın Öçal fullname: Akın Öçal, Fatma Ceyda organization: Health Sciences University, Gülhane Training and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Ankara, Turkey – sequence: 3 givenname: Mustafa surname: Güllüev fullname: Güllüev, Mustafa organization: Health Sciences University, Konya Training and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey – sequence: 4 givenname: Necat surname: Alataş fullname: Alataş, Necat organization: Health Sciences University, Konya Training and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30522831$$D View this record in MEDLINE/PubMed |
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DocumentTitleAlternate | A relação proteína C-reativa/albumina é um fator prognóstico e preditivo na surdez súbita? |
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Keywords | Albumina C-reactive protein Chronic inflammation Sudden hearing loss Perda auditiva súbita Albumin Proteína C-reativa Inflamação crônica |
Language | English |
License | This is an open access article under the CC BY license. Copyright © 2018 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). This work is licensed under a Creative Commons Attribution 4.0 International License. http://creativecommons.org/licenses/by/4.0 |
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publication-title: Eur Ann Otorhinolaryngol Head Neck Dis doi: 10.1016/j.anorl.2016.06.005 – volume: 15 start-page: 350 year: 2015 ident: 10.1016/j.bjorl.2018.10.007_bib0235 article-title: A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio publication-title: BMC Cancer doi: 10.1186/s12885-015-1379-6 – volume: 7 start-page: 1406 year: 2016 ident: 10.1016/j.bjorl.2018.10.007_bib0240 article-title: Exploration and validation of C-reactive protein/albumin ratio as a novel inflammation-based prognostic marker in nasopharyngeal carcinoma publication-title: J Cancer doi: 10.7150/jca.15401 – volume: 8 start-page: 467 year: 1975 article-title: The treatment of idiopathic sudden sensorineural hearing loss publication-title: Otolaryngol Clin North Am – volume: 29 start-page: 464 year: 2009 end-page: 479 article-title: Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects publication-title: J Cereb Blood Flow Metab – volume: 159 start-page: 313 year: 2012 end-page: 325 article-title: Biomarkers in inflammatory bowel disease: current practices and recent advances publication-title: Transl Res – volume: 7 start-page: 1406 year: 2016 end-page: 1412 article-title: Exploration and validation of C-reactive protein/albumin ratio as a novel inflammation-based prognostic marker in nasopharyngeal carcinoma publication-title: J Cancer – volume: 134 start-page: 383 year: 2017 end-page: 386 article-title: Are neutrophil/lymphocyte and platelet/lymphocyte ratios related with formation of sudden hearing loss and its prognosis? publication-title: Eur Ann Otorhinolaryngol Head Neck Dis – volume: 26 start-page: 387 year: 2012 end-page: 396 article-title: Polymorphisms in genes involved in inflammatory pathways in patients with sudden sensorineural hearing loss publication-title: J Neurogenet – volume: 5 start-page: 10481 year: 2015 article-title: Ratio of Creactive protein/albumin is an inflammatory prognostic score for predicting overall survival of patients with small-cell lung cancer publication-title: Sci Rep – volume: 17 start-page: 432 year: 2004 end-page: 437 article-title: Serum albumin: relationship to inflammation and nutrition publication-title: Semin Dial – volume: 27 start-page: 604 year: 2006 end-page: 608 article-title: Comparison of intratympanic and intravenous dexamethasone treatment of sudden senorineural hearing loss with diabetes publication-title: Otol Neurotol – volume: 33 start-page: 1142 year: 2012 end-page: 1150 article-title: Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss publication-title: Otol Neurotol – volume: 83 start-page: 575 year: 2006 end-page: 583 article-title: Proinflammatory cytokines expression in noise-induced damaged cochlea publication-title: J Neurosci Res – volume: 25 start-page: 276 year: 2010 end-page: 281 article-title: Prognostic factors of mortality in patients with community-acquired bloodstream infection with severe sepsis and septic shock publication-title: J Crit Care – volume: 8 start-page: 339 year: 2015 end-page: 345 article-title: Preoperative C-reactive protein/albumin ratio predicts prognosis of patients after curative resection for gastric cancer publication-title: Transl Oncol – volume: 86 start-page: 463 year: 1977 end-page: 468 article-title: Natural history of sudden sensorineural hearing loss publication-title: Ann Otol Rhinol Laryngol – volume: 375 start-page: 1203 year: 2010 end-page: 1211 article-title: Sudden sensorineural hearing loss publication-title: Lancet – volume: 34 start-page: 1400 year: 2013 end-page: 1404 article-title: Neutrophil-to-lymphocyte ratio as a new, quick, and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss publication-title: Otol Neurotol – volume: 22 start-page: 4393 year: 2016 end-page: 4400 article-title: Serum albumin and C-reactive protein/albumin ratio are useful biomarkers of Crohn's disease activity publication-title: Med Sci Monit – volume: 22 start-page: 803 year: 2015 end-page: 810 article-title: The C-reactive protein/albumin ratio, a novel inflammation-based prognostic score, predicts outcomes in patients with hepatocellular carcinoma publication-title: Ann Surg Oncol – volume: 7 start-page: 19 year: 1980 end-page: 22 article-title: Association of a low serum albumin with infection and increased mortality in critically ill patients publication-title: Intensive Care Med – volume: 15 start-page: 350 year: 2015 article-title: A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio publication-title: BMC Cancer – volume: 40 start-page: 1855 year: 2005 end-page: 1857 article-title: Pilot study evaluating C-reactive protein levels in the assessment of response to treatment of severe bloodstream infection publication-title: Clin Infect Dis – volume: 106 start-page: 772 year: 1980 end-page: 776 article-title: The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study publication-title: Arch Otolaryngol – volume: 10 start-page: R63 year: 2006 article-title: Early identification of intensive care unit-acquired infections with daily monitoring of C-reactive protein: a prospective observational study publication-title: Crit Care – volume: 34 start-page: 481 year: 2008 end-page: 487 article-title: C-reactive protein concentration as a predictor of in-hospital mortality after ICU discharge: a prospective cohort study publication-title: Intensive Care Med |
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Snippet | Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic inflammation. The... Abstract Introduction: Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with... Introduction: Sudden hearing loss is a significant otologic emergency. Previous studies have revealed a coexistence of sudden hearing loss with chronic... |
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SubjectTerms | Adult Albumin Albumina Biomarkers - blood C-reactive protein C-Reactive Protein - analysis Case-Control Studies Chronic inflammation Female Hearing Loss, Sensorineural - blood Hearing Loss, Sensorineural - drug therapy Hearing Loss, Sudden - blood Hearing Loss, Sudden - drug therapy Humans Inflamação crônica Lymphocyte Count Male Methylprednisolone - therapeutic use Middle Aged Neutrophils Original OTORHINOLARYNGOLOGY Perda auditiva súbita Predictive Value of Tests Prognosis Proteína C-reativa Retrospective Studies Serum Albumin - analysis Sudden hearing loss Treatment Outcome |
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Title | Is the C-reactive protein/albumin ratio a prognostic and predictive factor in sudden hearing loss? |
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