立体定向丘脑腹中间核毁损术治疗书写痉挛的疗效评估
目的探讨丘脑腹中间（Vim）核毁损术治疗书写痉挛的有效性和安全性。方法采用微电极引导下左侧丘脑Vim核毁损治疗书写痉挛（WC）患者47例,其中男32例,女15例;年龄15-64岁,平均（28.9±10.7）岁;病程2-21年。在术前和术后,采用书写痉挛评分量表（the writer＇s cramp rating scale,WCRS）对患者进行评分。结果全部患者毁损手术当时症状就明显改善,肘部、腕部和手指痉挛明显缓解,写字的流利程度和速度明显提升。其中2例患者（4.2%）出现一过性的右手指尖麻木;另有3例患者（6.4%）出现一过性言语不流利;上述并发症在3个月内完全恢复,没有永久性并发症发生。...
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| Published in | 临床神经外科杂志 Vol. 13; no. 6; pp. 412 - 414 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
10053 北京,首都医科大学宣武医院功能神经外科,北京市功能神经外科研究所
2016
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-7770 |
| DOI | 10.3969/j.issn.1672-7770.2016.06.004 |
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| Abstract | 目的探讨丘脑腹中间（Vim）核毁损术治疗书写痉挛的有效性和安全性。方法采用微电极引导下左侧丘脑Vim核毁损治疗书写痉挛（WC）患者47例,其中男32例,女15例;年龄15-64岁,平均（28.9±10.7）岁;病程2-21年。在术前和术后,采用书写痉挛评分量表（the writer＇s cramp rating scale,WCRS）对患者进行评分。结果全部患者毁损手术当时症状就明显改善,肘部、腕部和手指痉挛明显缓解,写字的流利程度和速度明显提升。其中2例患者（4.2%）出现一过性的右手指尖麻木;另有3例患者（6.4%）出现一过性言语不流利;上述并发症在3个月内完全恢复,没有永久性并发症发生。术后对患者进行电话随访,随访时间6-36个月,平均23个月;结果显示,患者的症状改善稳定;其中有3例患者失随访。另外,有1例患者因症状反复,再次行丘脑Vim核毁损术,术后症状改善明显。结论丘脑Vim核毁损术治疗书写痉挛是一种有效、安全的手术方式。 |
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| AbstractList | 目的探讨丘脑腹中间（Vim）核毁损术治疗书写痉挛的有效性和安全性。方法采用微电极引导下左侧丘脑Vim核毁损治疗书写痉挛（WC）患者47例,其中男32例,女15例;年龄15-64岁,平均（28.9±10.7）岁;病程2-21年。在术前和术后,采用书写痉挛评分量表（the writer＇s cramp rating scale,WCRS）对患者进行评分。结果全部患者毁损手术当时症状就明显改善,肘部、腕部和手指痉挛明显缓解,写字的流利程度和速度明显提升。其中2例患者（4.2%）出现一过性的右手指尖麻木;另有3例患者（6.4%）出现一过性言语不流利;上述并发症在3个月内完全恢复,没有永久性并发症发生。术后对患者进行电话随访,随访时间6-36个月,平均23个月;结果显示,患者的症状改善稳定;其中有3例患者失随访。另外,有1例患者因症状反复,再次行丘脑Vim核毁损术,术后症状改善明显。结论丘脑Vim核毁损术治疗书写痉挛是一种有效、安全的手术方式。 R454.1%R322.81; 目的 探讨丘脑腹中间(Vim)核毁损术治疗书写痉挛的有效性和安全性.方法 采用微电极引导下左侧丘脑Vim核毁损治疗书写痉挛(WC)患者47例,其中男32例,女15例;年龄15~64岁,平均(28.9±10.7)岁;病程2~21年.在术前和术后,采用书写痉挛评分量表(the writer's cramp rating scale,WCRS)对患者进行评分.结果 全部患者毁损手术当时症状就明显改善,肘部、腕部和手指痉挛明显缓解,写字的流利程度和速度明显提升.其中2例患者(4.2%)出现一过性的右手指尖麻木;另有3例患者(6.4%)出现一过性言语不流利;上述并发症在3个月内完全恢复,没有永久性并发症发生.术后对患者进行电话随访,随访时间6~36个月,平均23个月;结果显示,患者的症状改善稳定;其中有3例患者失随访.另外,有1例患者因症状反复,再次行丘脑Vim核毁损术,术后症状改善明显.结论 丘脑Vim核毁损术治疗书写痉挛是一种有效、安全的手术方式. |
| Abstract_FL | Objective To explore the efficacy and safety of stereotactic selective thalamotomy for the treatment of writer's cramp( WC) .Methods 47 patients(32 men,15 women,age 15-64 years, mean 28.9 years) with medically intractable task-specific focal dystonia of the hand underwent Vim thalamotomy.The stereotactic target was chosen at ventralis intermedius nucleus. The mean duration of the symptom ranged from 2 to 21 years ( mean 5 .5 years ) .Results All patients showed immediate postoperative disappearance of dystonic symptoms , and the effect was sustained during the follow-up period ( 6-36 months, mean 23 months ) , except in 3 cases.One patient showed partial recurrence of the symptom and underwent second thalamotomy 6 months after the initial surgery with satisfactory results.The score on WC rating scale decreased significantly (P<0.001) after Vim thalamotomy.There were no permanent operative complications.There was no mortality or permanent morbidity.Conclusion Although a longer follow-up is needed, stereotactic Vim thalamotomy is a useful and safe therapeutic option for writer's cramp. |
| Author | 李建宇 张宇清 庄平 李勇杰 |
| AuthorAffiliation | 首都医科大学宣武医院功能神经外科,北京市功能神经外科研究所,北京10053 |
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| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
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| Keywords | 脑深部核团毁损术 书写痉挛 writer's cramp 丘脑腹中间核 ventralis intermedius nucleus of thalamotomy |
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| Notes | LI Jian-yu, ZHANG Yu-qing, ZHUANG Ping, et al（ Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beifing 100053, China） writer＇s cramp; ventralis intermedius nucleus of thalamotomy Objective To explore the efficacy and safety of stereotactic selective thalamotomy for the treatment of writer＇s cramp（ WC）. Methods 47 patients（ 32 men,15 women,age 15- 64 years,mean 28. 9 years） with medically intractable task-specific focal dystonia of the hand underwent Vim thalamotomy. The stereotactic target was chosen at ventralis intermedius nucleus.The mean duration of the symptom ranged from 2 to 21 years（ mean 5. 5 years）. Results All patients showed immediate postoperative disappearance of dystonic symptoms,and the effect was sustained during the follow-up period（ 6-36 months,mean 23 months）,except in 3 cases. One patient showed partial recurrence of the symptom and underwent second thalamotomy 6 months after the initial surgery with satisfactory results. The score on WC rating sca |
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| PublicationTitle | 临床神经外科杂志 |
| PublicationTitleAlternate | Journal of Clinical Neurosurgery |
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| PublicationYear | 2016 |
| Publisher | 10053 北京,首都医科大学宣武医院功能神经外科,北京市功能神经外科研究所 |
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| Snippet | 目的探讨丘脑腹中间（Vim）核毁损术治疗书写痉挛的有效性和安全性。方法采用微电极引导下左侧丘脑Vim核毁损治疗书写痉挛（WC）患者47例,其中男32例,女15例;年龄15-64岁,平... R454.1%R322.81; 目的 探讨丘脑腹中间(Vim)核毁损术治疗书写痉挛的有效性和安全性.方法 采用微电极引导下左侧丘脑Vim核毁损治疗书写痉挛(WC)患者47例,其中男32例,女15例;... |
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| Title | 立体定向丘脑腹中间核毁损术治疗书写痉挛的疗效评估 |
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