Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm - Wicks, Paul; Vaughan, Timothy E; Massagli, Michael P; Heywood, James (Nature biotechnology, 2011)
Keywords: 631/114/2401; 631/378/1689/1285; 692/700/565/1436; Agriculture; Algorithms; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - drug therapy; analysis; Bioinformatics; Biological and medical sciences; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Biomedicine; Biotechnology; Care and treatment; Case-Control Studies; Clinical trials; Control algorithms; Drug therapy; Female; Fundamental and applied biological sciences. Psychology; General aspects; Health aspects; Humans; Internet; Life Sciences; Lithium; Lithium carbonate; Lithium Carbonate - blood; Lithium Carbonate - therapeutic use; Male; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Middle Aged; Observational studies; Online health care information services; Riluzole - administration & dosage; Risk Factors; Self Report; Sex Distribution; Treatment Outcome; United States; Drug; Data analysis; On line; Treatment; Efficiency; Patient; Amyotrophic lateral sclerosis; Lithium carbonate; Web site; Algorithm; Computational biology