妊娠期泛发性脓疱型银屑病的诊疗进展

妊娠期泛发性脓疱型银屑病是一种罕见而严重的银屑病。该病发病突然，发展迅速，以全身泛发无菌性脓疱伴严重全身症状为特征，常伴发热、白细胞增多和低蛋白血症等，病情严重，可危及母儿生命。妊娠期泛发性脓疱型银屑病的发病机制仍不清楚，糖皮质激素和维甲酸为治疗常用药物，但由于妊娠期用药受到限制，其治疗依然是非常棘手的问题。早期明确诊断、及时综合治疗并适时终止妊娠有望获得良好的母儿结局。现就妊娠期泛发性脓疱型银屑病的诊断及治疗研究进展进行综述。...

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Published in国际妇产科学杂志 Vol. 41; no. 2; pp. 175 - 177
Main Author 杜莹莹 赵先兰
Format Journal Article
LanguageChinese
Published 450052,郑州大学第一附属医院妇产科 2014
Subjects
孕妇
治疗
诊断
银屑病
银屑病
治疗
Therapy
诊断
Psoriasis
Pregnant women
孕妇
Diagnosis
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ISSN1674-1870

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Summary:妊娠期泛发性脓疱型银屑病是一种罕见而严重的银屑病。该病发病突然，发展迅速，以全身泛发无菌性脓疱伴严重全身症状为特征，常伴发热、白细胞增多和低蛋白血症等，病情严重，可危及母儿生命。妊娠期泛发性脓疱型银屑病的发病机制仍不清楚，糖皮质激素和维甲酸为治疗常用药物，但由于妊娠期用药受到限制，其治疗依然是非常棘手的问题。早期明确诊断、及时综合治疗并适时终止妊娠有望获得良好的母儿结局。现就妊娠期泛发性脓疱型银屑病的诊断及治疗研究进展进行综述。
Bibliography:Generalized pustular psoriasis of pregnancy is a rare and severe disease. The development is rapid ,with systemic generalized aseptic blain and severe systemic symptom for features,often associated with fever,hyperleukocytosis and hypoproteinemia,etc. It is a life-threatening disease either for pregnant woman or infant. The pathogenesis of the disease has not been illustrated completely. Glucocorticoid and retinoic acid are commonly used to treat this disease ,because the drugs used during pregnancy is restricted, the treatment is still difficult. Early diagnosis ,treatment and terminate pregnancy timely can improve the maternal and perinatal prognosis of this disease. This article is to review diagnosis and treatment progress of this disease.
Pregnant women;Psoriasis;Diagnosis;Therapy
12-1399/R
DU Ying-ying, ZHAO Xian-lan （Department of Obstetrics and Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China）
ISSN:1674-1870