Quercetin improves epithelial regeneration from airway basal cells of COPD patients - McCluskey, Elizabeth S.; Liu, Nathan; Pandey, Abhimaneu; Marchetti, Nathaniel; Kelsen, Steven G.; Sajjan, Umadevi S. (Respiratory research, 2024)
Keywords: Analysis; Anopheles; Antibodies; Basal cells; Bronchi - metabolism; Cell culture; Cell differentiation; Cell growth; Cells, Cultured; Chronic obstructive pulmonary disease; Clinical trials; Cytotoxicity; Development and progression; Dimethyl Sulfoxide - metabolism; Dimethyl Sulfoxide - pharmacology; DNA microarrays; ELF3; Enzyme-linked immunosorbent assay; Epigenetics; Epithelial Cells - metabolism; Epithelium; Flow cytometry; Gene expression; Genes; Genetic aspects; Goblet cell metaplasia; Goblet cells; Homeodomain Proteins - metabolism; Homeodomain Proteins - pharmacology; HOXB2; Humans; Hyperplasia; Interleukin 8; Interleukin-8 - metabolism; Kinases; Lung diseases; Lung diseases, Obstructive; Lungs; Medicine; Medicine & Public Health; Obstructive lung disease; Ontology; Patients; Placebos; Pneumology/Respiratory System; Pulmonary Disease, Chronic Obstructive - diagnosis; Pulmonary Disease, Chronic Obstructive - drug therapy; Pulmonary Disease, Chronic Obstructive - genetics; Quercetin; Quercetin - metabolism; Quercetin - pharmacology; Quercetin - therapeutic use; Regeneration; Respiratory tract diseases; RNA; Smoking; Stem cells; Transcription Factors - metabolism; Transforming growth factor-b; Transforming growth factors; Goblet cell metaplasia; HOXB2; Chronic obstructive pulmonary disease; ELF3