Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia - Tubío-Santamaría, Nuria; Jayavelu, Ashok Kumar; Schnoeder, Tina M.; Eifert, Theresa; Hsu, Chen-Jen; Perner, Florian; Zhang, Qirui; Wenge, Daniela V.; Hansen, Fynn M.; Kirkpatrick, Joanna M.; Jyotsana, Nidhi; Lane, Steven W.; et al. (Molecular cancer, 2023)
Keywords: Acute myeloid leukemia; Animals; Biomedical and Life Sciences; Biomedicine; Bone marrow; Cancer; Cancer Research; Carfilzomib; Cell cycle; Cell growth; Cell proliferation; Chromatin; Epigenetics; Fusion protein; Gene Expression; Gene silencing; Genes; Genetic aspects; Genetic transcription; Health aspects; Hematopoietic stem cells; Humans; Leukemia; Leukemia, Myeloid, Acute - metabolism; Medical prognosis; Mice; Mutation; Myeloid-Lymphoid Leukemia Protein - genetics; Myeloid-Lymphoid Leukemia Protein - metabolism; Oncology; Proteins; Proteomics; Scientific equipment and supplies industry; Therapeutic targets; Transcription Factors - genetics; United States; Germany