Effect of single doses of IV palonosetron, up to 2.25 mg, on the QTc interval duration: a double-blind, randomized, parallel group study in healthy volunteers - Morganroth, Joel; Flaharty, Kristen K.; Parisi, Simona; Moresino, Cecilia (Supportive care in cancer, 2016)
Keywords: Administration, Intravenous; Adult; Chemotherapy; Clinical trials; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Electrocardiography - drug effects; Female; Heart Rate - drug effects; Humans; Isoquinolines - administration & dosage; Isoquinolines - adverse effects; Male; Medicine; Medicine & Public Health; Middle Aged; Nausea; Nursing; Nursing Research; Oncology; Original; Original Article; Pain Medicine; Quinuclidines - administration & dosage; Quinuclidines - adverse effects; Reference Values; Rehabilitation Medicine; Serotonin Antagonists - administration & dosage; Serotonin Antagonists - adverse effects; Strategic planning (Business); Studies; Volunteers; QTc interval; 5-HT; receptor antagonists; Palonosetron; Chemotherapy-induced nausea and vomiting; 5-HT3 receptor antagonists