Identification of a small mutation panel of coding sequences to predict the efficacy of immunotherapy for lung adenocarcinoma - Li, Ying; Jiang, Wenbin; Li, Tianhao; Li, Mengyue; Li, Xin; Zhang, Zheyang; Zhang, Sainan; Liu, Yixin; Zhao, Wenyuan; Gu, Yunyan; Qi, Lishuang; Ao, Lu; et al. (Journal of translational medicine, 2020)
Keywords: Adenocarcinoma; Adenocarcinoma of Lung - drug therapy; Adenocarcinoma of Lung - genetics; Algorithms; Biomarkers, Tumor; Biomedical and Life Sciences; Biomedicine; Cancer research; Care and treatment; CDS mutation panel; Clinical application; Clinical medicine; Cytotoxicity; Datasets; Female; Gene mutation; Genes; Genetic algorithms; Genetic aspects; Genomes; Genomics; Health aspects; Humans; Immune checkpoint inhibitors; Immunotherapy; Ipilimumab; Ligands; Lung adenocarcinoma; Lung cancer; Lung Neoplasms - drug therapy; Lung Neoplasms - genetics; Male; Medical research; Medicine/Public Health; Monoclonal antibodies; Mutation; Mutation - genetics; Nivolumab; Patient outcomes; Pembrolizumab; Personalized medicine; Protein expression; Proteins; Regression analysis; Retirement benefits; Survival; Survival analysis; Targeted cancer therapy; Therapeutic applications; Time; Tumors; Tumour mutation burden; China; Tumour mutation burden; CDS mutation panel; Lung adenocarcinoma; Clinical application; Immunotherapy