Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis - Hansen, Henrik H.; Ægidius, Helene M.; Oró, Denise; Evers, Simon S.; Heebøll, Sara; Eriksen, Peter Lykke; Thomsen, Karen Louise; Bengtsson, Anja; Veidal, Sanne S.; Feigh, Michel; Suppli, Malte P.; Knop, Filip K.; et al. (BMC gastroenterology, 2020)
Keywords: Amylin; Animal models; Animals; Balloon treatment; Biopsy; Care and treatment; Cholesterol; Collagen; Degeneration; Diagnosis; Diet; Diet, High-Fat - adverse effects; Diet-induced obesity; Disease Models, Animal; Drug therapy; Fasting; Fatty acids; Fatty liver; Fibrosis; Gastroenterology; Gene expression; Genomes; Glucose; Glucose tolerance; Health aspects; Health care; Hepatitis; Hepatobiliary and pancreatic disorders; Hepatology; Histomorphometry; Histopathology; Humans; Inflammation; Insulin resistance; Internal Medicine; Laboratory animals; Liver; Liver diseases; Medicine; Medicine & Public Health; Metabolic syndrome; Metabolism; Mice; Mice, Inbred C57BL; Mice, Obese; Mouse model; Non-alcoholic Fatty Liver Disease; Non-alcoholic steatohepatitis; Obesity; Obesity - complications; Oils & fats; Physical characteristics; Plasma; Research Article; Semiconductors; Therapeutic applications; Transcription; Translatability; United States; Denmark; Aarhus Denmark; Glucose tolerance; Diet-induced obesity; Histopathology; Mouse model; Non-alcoholic steatohepatitis; Histomorphometry; Translatability; Liver transcriptome