Rap1 in the VMH regulates glucose homeostasis - Kaneko, Kentaro; Lin, Hsiao-Yun; Fu, Yukiko; Saha, Pradip K.; De la Puente-Gomez, Ana B.; Xu, Yong; Ohinata, Kousaku; Chen, Peter; Morozov, Alexei; Fukuda, Makoto (JCI insight, 2021)
Keywords: Animal models; Animals; Antidiabetics; Blood glucose; Blood Glucose - metabolism; Body weight gain; Diabetes; Diabetes mellitus; Diet, High-Fat; Energy balance; Forebrain; Gene Knockdown Techniques; Glucose; Glucose metabolism; Glucose tolerance; High fat diet; Homeostasis; Hyperglycemia; Hyperglycemia - metabolism; Hypothalamus; Hypothalamus (medial); Hypothalamus (ventromedial); Hypothalamus - metabolism; Insulin - metabolism; Insulin Resistance; Leptin; Leptin - metabolism; Metabolism; Mice; Neurons - metabolism; Neuroscience; Nutrient deficiency; Obesity; Obesity - metabolism; rap1 GTP-Binding Proteins - genetics; rap1 GTP-Binding Proteins - metabolism; Rap1 protein; Steroidogenic Factor 1 - metabolism; Ventromedial Hypothalamic Nucleus - metabolism; Glucose metabolism; Signal transduction; Neuroscience; G proteins; Metabolism