Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer - Liu, David; Abbosh, Philip; Keliher, Daniel; Reardon, Brendan; Miao, Diana; Mouw, Kent; Weiner-Taylor, Amaro; Wankowicz, Stephanie; Han, Garam; Teo, Min Yuen; Cipolla, Catharine; Kim, Jaegil; et al. (Nature communications, 2017)
Keywords: 631/67/2329; 631/67/589/1336; 631/67/69; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols - pharmacology; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biomarkers; Biomarkers, Tumor - genetics; Bladder; Bladder cancer; Cancer; Carcinoma - drug therapy; Carcinoma - genetics; Carcinoma - mortality; Carcinoma - pathology; Chemotherapy; Cisplatin; Cisplatin - pharmacology; Cisplatin - therapeutic use; Clinical trials; Clonal Evolution - drug effects; Cohort Studies; Cystectomy; DNA Mutational Analysis; Drug Resistance, Neoplasm - drug effects; Drug Resistance, Neoplasm - genetics; Female; Gene expression; Gene regulation; Heterogeneity; Humanities and Social Sciences; Humans; Immune checkpoint; Invasiveness; Male; Middle Aged; multidisciplinary; Muscles; Mutation; Neoadjuvant Therapy - methods; Neoplasm Invasiveness; Science; Science (multidisciplinary); Spatial heterogeneity; Survival Rate; Transcriptome - genetics; Treatment Outcome; Tumors; Urinary bladder; Urinary Bladder - pathology; Urinary Bladder - surgery; Urinary Bladder Neoplasms - drug therapy; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - mortality; Urinary Bladder Neoplasms - surgery; Whole Exome Sequencing