霜天蛾过敏性哮喘患者特异性免疫治疗的效果评价

目的 观察霜天蛾过敏性哮喘患者特异性免疫治疗(SIT)的疗效。方法 对64例确诊为霜天蛾过敏性哮喘(NA)患者注射霜天蛾变应原浸液，观察临床疗效和SIT前后皮内试验风团直径、淋巴细胞亚群(CD4、CD8、CD4／CD8)、免疫球蛋白（IgG、IgA、IgE)、肺功能(FEV1、PEFR)及支气管激发试验(PD20—F2EV1)的变化。结果 SIT总有效率为76．5％(49／64)。SIT后皮内试验风团直径缩小，CD8细胞增加，CD4／CD8比例下降，IgE降低，IgG和IgA增高，PEV1、PEFR、PD20—FEV1均增加，(P值均＜0．01)。结论 SIT对过敏性哮喘有较好的临床疗效，能增...

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Published inXi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban Vol. 24; no. 3; pp. 237 - 238
Main Author 李雅莉 孙秀珍 张洁 冯向莉
Format Journal Article
LanguageChinese
Published 西安交通大学第二医院呼吸科,陕西西安,710004 2003
Subjects
免疫球蛋白
副作用
淋巴细胞亚群
特异性免疫治疗
疗效
过敏性哮喘
霜天蛾
特异性免疫治疗
霜天蛾
过敏性哮喘
Online AccessGet full text
ISSN1671-8259
DOI10.3969/j.issn.1671-8259.2003.03.016

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Abstract 目的 观察霜天蛾过敏性哮喘患者特异性免疫治疗(SIT)的疗效。方法 对64例确诊为霜天蛾过敏性哮喘(NA)患者注射霜天蛾变应原浸液，观察临床疗效和SIT前后皮内试验风团直径、淋巴细胞亚群(CD4、CD8、CD4／CD8)、免疫球蛋白（IgG、IgA、IgE)、肺功能(FEV1、PEFR)及支气管激发试验(PD20—F2EV1)的变化。结果 SIT总有效率为76．5％(49／64)。SIT后皮内试验风团直径缩小，CD8细胞增加，CD4／CD8比例下降，IgE降低，IgG和IgA增高，PEV1、PEFR、PD20—FEV1均增加，(P值均＜0．01)。结论 SIT对过敏性哮喘有较好的临床疗效，能增强患者的细胞免疫和体液免疫功能，改善肺通气功能，降低气道高反应性。
AbstractList R562.25; 目的观察霜天蛾过敏性哮喘患者特异性免疫治疗(SIT)的疗效.方法对64例确诊为霜天蛾过敏性哮喘(PAA)患者注射霜天蛾变应原浸液,观察临床疗效和SIT前后皮内试验风团直径、淋巴细胞亚群(CD4、CD8、CD4/CD8)、免疫球蛋白(IgG、IgA、IgE)、肺功能(FEV1、PEFR)及支气管激发试验(PD20-FEV1)的变化.结果 SIT总有效率为76.5%(49/64).SIT后皮内试验风团直径缩小,CD8细胞增加,CD4/CD8比例下降,IgE降低,IgG和IgA增高,FEV1、PEFR、PD20-FEV1均增加,(P值均<0.01).结论 SIT对过敏性哮喘有较好的临床疗效,能增强患者的细胞免疫和体液免疫功能,改善肺通气功能,降低气道高反应性.
目的 观察霜天蛾过敏性哮喘患者特异性免疫治疗(SIT)的疗效。方法 对64例确诊为霜天蛾过敏性哮喘(NA)患者注射霜天蛾变应原浸液，观察临床疗效和SIT前后皮内试验风团直径、淋巴细胞亚群(CD4、CD8、CD4／CD8)、免疫球蛋白（IgG、IgA、IgE)、肺功能(FEV1、PEFR)及支气管激发试验(PD20—F2EV1)的变化。结果 SIT总有效率为76．5％(49／64)。SIT后皮内试验风团直径缩小，CD8细胞增加，CD4／CD8比例下降，IgE降低，IgG和IgA增高，PEV1、PEFR、PD20—FEV1均增加，(P值均＜0．01)。结论 SIT对过敏性哮喘有较好的临床疗效，能增强患者的细胞免疫和体液免疫功能，改善肺通气功能，降低气道高反应性。
Author 李雅莉 孙秀珍 张洁 冯向莉
AuthorAffiliation 西安交通大学第二医院呼吸科，陕西西安710004
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Snippet 目的 观察霜天蛾过敏性哮喘患者特异性免疫治疗(SIT)的疗效。方法 对64例确诊为霜天蛾过敏性哮喘(NA)患者注射霜天蛾变应原浸液，观察临床疗效和SIT前后皮内试验风团直径、淋...
R562.25; 目的观察霜天蛾过敏性哮喘患者特异性免疫治疗(SIT)的疗效.方法对64例确诊为霜天蛾过敏性哮喘(PAA)患者注射霜天蛾变应原浸液,观察临床疗效和SIT前后皮内试验风团...
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StartPage 237
SubjectTerms 免疫球蛋白
副作用
淋巴细胞亚群
特异性免疫治疗
疗效
过敏性哮喘
霜天蛾
Title 霜天蛾过敏性哮喘患者特异性免疫治疗的效果评价
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