Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy - Makovec, Tomaz (Radiology and oncology, 2019)
Keywords: Adducts; Anticancer properties; Antineoplastic Agents - adverse effects; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacokinetics; Antineoplastic Agents - pharmacology; Antineoplastic drugs; Antitumor activity; Antitumor agents; Cancer; Chemical properties; Chemotherapy; Cisplatin; Cisplatin - adverse effects; Cisplatin - chemistry; Cisplatin - pharmacokinetics; Cisplatin - pharmacology; Deoxyribonucleic acid; DNA; DNA adducts; DNA Adducts - chemistry; DNA Repair; DNA, Neoplasm - drug effects; Drug development; Drug Hypersensitivity - etiology; Drug resistance; Drug Resistance, Neoplasm - genetics; Drug Resistance, Neoplasm - physiology; Drugs; Gene expression; Genomics; Gold Compounds - pharmacology; Humans; Metabolic pathways; Metal compounds; molecular mechanisms; Molecular modelling; Neoplasms; Neoplasms - blood; Neoplasms - drug therapy; Organic chemistry; Organometallic Compounds - chemistry; Organometallic Compounds - pharmacology; Palladium - pharmacology; Platinum; Platinum Compounds - adverse effects; Platinum Compounds - pharmacokinetics; Platinum Compounds - pharmacology; Polymorphism, Genetic; resistance; Review; Ribonucleic acid; RNA; Ruthenium - pharmacology; Toxicity; molecular mechanisms; cisplatin; chemotherapy; resistance