Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer’s disease - Landlinger, Christine; Oberleitner, Lisa; Gruber, Petra; Noiges, Birgit; Yatsyk, Kristyna; Santic, Radmila; Mandler, Markus; Staffler, Guenther (Journal of neuroinflammation, 2015)
Keywords: Advertising executives; Alzheimer Disease - drug therapy; Alzheimer Disease - psychology; Alzheimer Vaccines - therapeutic use; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Analysis; Animals; Antigenic determinants; Biomedical and Life Sciences; Biomedicine; Brain; Care and treatment; Complement C5a - immunology; Complement C5a - metabolism; Complications and side effects; Enzyme-linked immunosorbent assay; Fear; Female; Health aspects; Immunization Schedule; Immunology; Inflammation - drug therapy; Inflammation - pathology; Macrophage Activation - drug effects; Male; Memory; Mice; Microglia - drug effects; Neurobiology; Neurology; Neurosciences; Plaque, Amyloid - pathology; Proteins; Psychomotor Performance; Risk factors; Vaccination; Vaccines, Subunit - therapeutic use; Contextual Fear Conditioning; Time Freezing; Tg2576 Mouse; Biweekly Interval; Amyloid Plaque