Pulmonary hypertension and vascular remodeling in mice exposed to crystalline silica - Zelko, Igor N.; Zhu, Jianxin; Ritzenthaler, Jeffrey D.; Roman, Jesse (Respiratory research, 2016)
Keywords: Animal models; Animals; Collagen - metabolism; Development and progression; Extracellular Matrix Proteins - metabolism; Gene Expression Regulation - drug effects; Hemodynamics - drug effects; Histology; Histopathology; Hypertension; Hypertension, Pulmonary - chemically induced; Hypertension, Pulmonary - pathology; Hypertrophy, Right Ventricular - chemically induced; Hypertrophy, Right Ventricular - pathology; Inflammation - chemically induced; Inflammation - pathology; Injections, Spinal; Lung - pathology; Male; Medicine; Medicine & Public Health; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular - drug effects; Muscle, Smooth, Vascular - pathology; Physiological aspects; Pneumology/Respiratory System; Pulmonary Fibrosis - chemically induced; Pulmonary Fibrosis - complications; Pulmonary Fibrosis - pathology; Pulmonary hypertension; Risk factors; Silica; Silicon Dioxide - toxicity; Silicosis; Silicosis - pathology; Vascular Remodeling - drug effects; United States; Vascular remodeling; Animal model; Silicosis; Pulmonary hypertension