Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency - Sancho-Shimizu, Vanessa; Pérez de Diego, Rebeca; Lorenzo, Lazaro; Halwani, Rabih; Alangari, Abdullah; Israelsson, Elisabeth; Fabrega, Sylvie; Cardon, Annabelle; Maluenda, Jerome; Tatematsu, Megumi; Mahvelati, Farhad; Herman, Melina; et al. (The Journal of clinical investigation, 2011)
Keywords: Adaptor Proteins, Vesicular Transport - deficiency; Adaptor Proteins, Vesicular Transport - genetics; Adaptor Proteins, Vesicular Transport - physiology; Amino Acid Sequence; Biomedical research; Care and treatment; Cellular proteins; Child, Preschool; Children; Codon, Nonsense; Consanguinity; DEAD-box RNA Helicases - physiology; Development and progression; Encephalitis; Encephalitis, Herpes Simplex - genetics; Families & family life; Female; Fibroblasts; Genes; Genes, Dominant; Genes, Recessive; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Health aspects; Herpes simplex encephalitis; Herpes viruses; Herpesvirus 1, Human; Humans; Infant; Infections; Infectious diseases; Interferon-alpha - biosynthesis; Interferon-alpha - genetics; Kinases; Leukocytes; Life Sciences; Male; Molecular Sequence Data; Mutation; Mutation, Missense; Patients; Pedigree; Properties; Proteins; Saudi Arabia; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction - physiology; Toll-Like Receptor 3 - physiology; Toll-Like Receptor 4 - physiology; Saudi Arabia; United States