肝细胞癌伴门静脉癌栓的介入综合治疗
伴门静脉癌栓（PVTT）的肝细胞癌（HCC）常见于进展期肝癌,PVTT可引起肿瘤播散、肝功能衰竭和门静脉高压,从而导致顽固性腹水、静脉曲张破裂和肝性脑病,严重影响肝癌患者预后。根据巴塞罗那临床肝癌分期（BCLC）,伴PVTT的进展期HCC,索拉非尼被推荐为一线治疗方案,但由于其疗效有限且价格昂贵限制了它在国内的应用。而介入治疗以其微创、可重复性等优点在临床得到广泛应用,并取得一定的疗效。目前主要应用的介入治疗方法包括：经肝动脉灌注化疗术（HAIC）、经肝动脉化疗栓塞术（TACE）、TACE联合索拉非尼、TACE联合消融术、TACE联合适形放疗、TACE联合门静脉支架、门静脉粒子条置放术、经颈静...
Saved in:
| Published in | 临床肝胆病杂志 Vol. 31; no. 6; pp. 863 - 869 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
苏州大学附属第一医院介入科,江苏苏州,215006
2015
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 |
| DOI | 10.3969/j.issn.1001-5256.2015.06.010 |
Cover
| Abstract | 伴门静脉癌栓（PVTT）的肝细胞癌（HCC）常见于进展期肝癌,PVTT可引起肿瘤播散、肝功能衰竭和门静脉高压,从而导致顽固性腹水、静脉曲张破裂和肝性脑病,严重影响肝癌患者预后。根据巴塞罗那临床肝癌分期（BCLC）,伴PVTT的进展期HCC,索拉非尼被推荐为一线治疗方案,但由于其疗效有限且价格昂贵限制了它在国内的应用。而介入治疗以其微创、可重复性等优点在临床得到广泛应用,并取得一定的疗效。目前主要应用的介入治疗方法包括：经肝动脉灌注化疗术（HAIC）、经肝动脉化疗栓塞术（TACE）、TACE联合索拉非尼、TACE联合消融术、TACE联合适形放疗、TACE联合门静脉支架、门静脉粒子条置放术、经颈静脉肝内门体分流术（TIPS）等。最后指出多种方法综合治疗有望取得较好疗效。 |
|---|---|
| AbstractList | 伴门静脉癌栓（PVTT）的肝细胞癌（HCC）常见于进展期肝癌,PVTT可引起肿瘤播散、肝功能衰竭和门静脉高压,从而导致顽固性腹水、静脉曲张破裂和肝性脑病,严重影响肝癌患者预后。根据巴塞罗那临床肝癌分期（BCLC）,伴PVTT的进展期HCC,索拉非尼被推荐为一线治疗方案,但由于其疗效有限且价格昂贵限制了它在国内的应用。而介入治疗以其微创、可重复性等优点在临床得到广泛应用,并取得一定的疗效。目前主要应用的介入治疗方法包括：经肝动脉灌注化疗术（HAIC）、经肝动脉化疗栓塞术（TACE）、TACE联合索拉非尼、TACE联合消融术、TACE联合适形放疗、TACE联合门静脉支架、门静脉粒子条置放术、经颈静脉肝内门体分流术（TIPS）等。最后指出多种方法综合治疗有望取得较好疗效。 R735.7; 伴门静脉癌栓(PVTT)的肝细胞癌(HCC)常见于进展期肝癌,PVTT可引起肿瘤播散、肝功能衰竭和门静脉高压,从而导致顽固性腹水、静脉曲张破裂和肝性脑病,严重影响肝癌患者预后.根据巴塞罗那临床肝癌分期(BCLC),伴PVTT的进展期HCC,索拉非尼被推荐为一线治疗方案,但由于其疗效有限且价格昂贵限制了它在国内的应用.而介入治疗以其微创、可重复性等优点在临床得到广泛应用,并取得一定的疗效.目前主要应用的介入治疗方法包括:经肝动脉灌注化疗术(HAIC)、经肝动脉化疗栓塞术(TACE)、TACE联合索拉非尼、TACE联合消融术、TACE联合适形放疗、TACE联合门静脉支架、门静脉粒子条置放术、经颈静脉肝内门体分流术(TIPS)等.最后指出多种方法综合治疗有望取得较好疗效. |
| Author | 朱晓黎 |
| AuthorAffiliation | 苏州大学附属第一医院介入科,江苏苏州215006 |
| AuthorAffiliation_xml | – name: 苏州大学附属第一医院介入科,江苏苏州,215006 |
| Author_FL | ZHU Xiaoli |
| Author_FL_xml | – sequence: 1 fullname: ZHU Xiaoli |
| Author_xml | – sequence: 1 fullname: 朱晓黎 |
| BookMark | eNo9j09Lw0AUxPdQwVr7JcSDl8T3drMvzVGK_6DgpfeSbJKaUjfaIGKPWkXRgyBYKlS8CJ7FW_px2ib9FkYqnoYZfswwa6ykYx0wtolgCoec7Y4ZJYk2EQANySWZHFCaQCYglFj5P19l1SSJPJAoyLEklZnIr8ZZeptfv2Wjx-nkezH8XIxH-eC-sPP35-x1ME0fZjcfWTqZPd3Nv9LsZbjOVkK3mwTVP62w5t5us35gNI72D-s7DUMRgEFIyufCcyRXgS-5y4kHHKSwArumamjxkKNn--jxkOxAFJ7QtS2SSjkhB1FhW8vaC1eHrm63OvF5TxeDra5q-16__3sSqLhYoBtLVB3Hun0WFfBpLzpxe5ctImkRIljiB9ZlZ0Q |
| ClassificationCodes | R735.7 |
| ContentType | Journal Article |
| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| Copyright_xml | – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| DBID | 2RA 92L CQIGP W91 ~WA 2B. 4A8 92I 93N PSX TCJ |
| DOI | 10.3969/j.issn.1001-5256.2015.06.010 |
| DatabaseName | 维普期刊资源整合服务平台 中文科技期刊数据库-CALIS站点 维普中文期刊数据库 中文科技期刊数据库-医药卫生 中文科技期刊数据库- 镜像站点 Wanfang Data Journals - Hong Kong WANFANG Data Centre Wanfang Data Journals 万方数据期刊 - 香港版 China Online Journals (COJ) China Online Journals (COJ) |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitleAlternate | Comprehensive interventional treatment of hepatocellular carcinoma with portal vein tumor thrombosis |
| DocumentTitle_FL | Comprehensive interventional treatment of hepatocellular carcinoma with portal vein tumor thrombosis |
| EndPage | 869 |
| ExternalDocumentID | lcgdbzz201506010 665461104 |
| GroupedDBID | -05 2B. 2C~ 2RA 5XA 5XF 92F 92I 92L ABDBF ACGFS ALMA_UNASSIGNED_HOLDINGS CCEZO CIEJG CQIGP CW9 EAD EAP EOJEC ESX GROUPED_DOAJ IPNFZ OBODZ OK1 RIG RNS TCJ TGQ U1G U5O W91 ~WA 4A8 93N ABJNI ACUHS PSX |
| ID | FETCH-LOGICAL-c600-616cd23b952ced52a262e20534e78c8142f21b7d1b2f67e342f61a7465cc9f203 |
| ISSN | 1001-5256 |
| IngestDate | Thu May 29 03:59:49 EDT 2025 Wed Feb 14 10:30:10 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | 综合疗法 combined modality therapy portal vein tumor thrombosis carcinoma,hepatocellular 门静脉癌栓 癌,肝细胞 |
| Language | Chinese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c600-616cd23b952ced52a262e20534e78c8142f21b7d1b2f67e342f61a7465cc9f203 |
| Notes | Portal vein tumor thrombosis（ PVTT） often occurs in advanced hepatocellular carcinoma（ HCC） patients. PVTT may cause tumor dissemination,liver failure,and portal hypertension,thus leading to intractable ascites,variceal rupture,and hepatic encephalopathy,which will result in a poor prognosis. According to the Barcelona Clinic Liver Cancer Staging System,sorafenib is recommended as the first- line treatment for advanced HCC with PVTT,but its application in China has been limited due to its mild efficacy and high price.Nowadays,interventional treatment is widely used in the treatment of advanced HCC with PVTT due to the advantages of minimal invasiveness and repeatability and shows good efficacy. At present,the main methods of interventional treatment include hepatic arterial infusion chemotherapy,transcatheter arterial chemoembolization（ TACE）,TACE combined with sorafenib,TACE combined with ablation,TACE combined with three- dimensional conformal radiotherapy,TACE combined with portal vein stent placement,endo |
| PageCount | 7 |
| ParticipantIDs | wanfang_journals_lcgdbzz201506010 chongqing_primary_665461104 |
| PublicationCentury | 2000 |
| PublicationDate | 2015 |
| PublicationDateYYYYMMDD | 2015-01-01 |
| PublicationDate_xml | – year: 2015 text: 2015 |
| PublicationDecade | 2010 |
| PublicationTitle | 临床肝胆病杂志 |
| PublicationTitleAlternate | Chinese Journal of Clinical Hepatology |
| PublicationTitle_FL | Journal of Clinical Hepatology |
| PublicationYear | 2015 |
| Publisher | 苏州大学附属第一医院介入科,江苏苏州,215006 |
| Publisher_xml | – name: 苏州大学附属第一医院介入科,江苏苏州,215006 |
| SSID | ssib051369456 ssj0041983 ssib001103858 ssib053243598 ssib002264326 ssib038074677 |
| Score | 2.0038993 |
| Snippet | 伴门静脉癌栓（PVTT）的肝细胞癌（HCC）常见于进展期肝癌,PVTT可引起肿瘤播散、肝功能衰竭和门静脉高压,从而导致顽固性腹水、静脉曲张破裂和肝性脑病,严重影响肝癌患者预后。... R735.7; 伴门静脉癌栓(PVTT)的肝细胞癌(HCC)常见于进展期肝癌,PVTT可引起肿瘤播散、肝功能衰竭和门静脉高压,从而导致顽固性腹水、静脉曲张破裂和肝性脑病,严重影响肝癌患者... |
| SourceID | wanfang chongqing |
| SourceType | Aggregation Database Publisher |
| StartPage | 863 |
| SubjectTerms | 癌,肝细胞 综合疗法 门静脉癌栓 |
| Title | 肝细胞癌伴门静脉癌栓的介入综合治疗 |
| URI | http://lib.cqvip.com/qk/90100X/201506/665461104.html https://d.wanfangdata.com.cn/periodical/lcgdbzz201506010 |
| Volume | 31 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVEBS databaseName: Academic Search Ultimate issn: 1001-5256 databaseCode: ABDBF dateStart: 20130401 customDbUrl: https://search.ebscohost.com/login.aspx?authtype=ip,shib&custid=s3936755&profile=ehost&defaultdb=asn isFulltext: true dateEnd: 99991231 titleUrlDefault: https://search.ebscohost.com/direct.asp?db=asn omitProxy: true ssIdentifier: ssj0041983 providerName: EBSCOhost – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources issn: 1001-5256 databaseCode: M~E dateStart: 19850101 customDbUrl: isFulltext: true dateEnd: 99991231 titleUrlDefault: https://road.issn.org omitProxy: true ssIdentifier: ssib053243598 providerName: ISSN International Centre |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NaxNBFB9iCsWL-Im1KhWcY-rufO3McTfZUIR6itBb2N1sUkFSP9JLTqJVFD0IgqVCxYvgWbylf07bpP-F781O0q1KUS_L7JvZN2_2zbz5zTDvDSG3_dTkUnFYqeYyqIkkZTXAyRxWKZ6X6ZxLEaC_8-o9tXJf3F2Ta5XKs9Kppc1BupwN_-hX8j9aBRroFb1k_0GzM6ZAgDToF56gYXj-lY5prKlm1DRoHNAoolpZCqcmRooxVNdpLGhUp5GgsaEmoKG2iQbmYmHAkqZUWNHQo4ZbSoi5-DlwjmgsqZY0lK4u4AkU41Gt8auIIRG_UrQ4CjuFvJaDtgJIGgHPsCS2lRbFDlA24A-sgA65WLg5ZQU9wuZAO3ybMFZGY0WLyzsXhdemM7N4kEuyIqT41A672eDBb0ZVOxPo5ufiapdfTT83yljTjxUszyrAw3vSRmh1p2dPBtfGu5cVICBxhswx3NGpkrkwakTNY0jpeyfi_aDjcQnyYrx-UQoJKH2ujDiOTyQBsGKQxCk6EL7RhdOHE3Aexksh_Z3TZMfQH-sb_d5jADTWv6zfTfq9EhRqnSfn3BpmKSw65AVSGa5fJPOr7pTGJcInz3fHo1eTF5_HO-_2934cbX872t2ZbL2B18MvH8aftvZHbw9efh2P9g7evz78Php_3L5MWs24VV-pucs5ahlgZBjLKuswnhrJsrwjWcIUyxk0V-SBzrQvWJf5adDxU9ZVQc7hXfkJ_CqZZabLPH6FVPsb_fwqWTJppjt5qj3RzQXvGphRMiNEEiQ8UdpLFsjirOntR0UMlvZMcQvklvsZbTcyn7YfZr1OOhyyInym7107lcMiOYsli32166Q6eLKZ3wCkOUhvus7wE52uXx8 |
| linkProvider | EBSCOhost |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%82%9D%E7%BB%86%E8%83%9E%E7%99%8C%E4%BC%B4%E9%97%A8%E9%9D%99%E8%84%89%E7%99%8C%E6%A0%93%E7%9A%84%E4%BB%8B%E5%85%A5%E7%BB%BC%E5%90%88%E6%B2%BB%E7%96%97&rft.jtitle=%E4%B8%B4%E5%BA%8A%E8%82%9D%E8%83%86%E7%97%85%E6%9D%82%E5%BF%97&rft.au=%E6%9C%B1%E6%99%93%E9%BB%8E&rft.date=2015&rft.issn=1001-5256&rft.volume=31&rft.issue=6&rft.spage=863&rft.epage=869&rft_id=info:doi/10.3969%2Fj.issn.1001-5256.2015.06.010&rft.externalDocID=665461104 |
| thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fimage.cqvip.com%2Fvip1000%2Fqk%2F90100X%2F90100X.jpg http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Flcgdbzz%2Flcgdbzz.jpg |