The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver - Patel, Kashyap; Foretz, Marc; Marion, Allison; Campbell, David G.; Gourlay, Robert; Boudaba, Nadia; Tournier, Emilie; Titchenell, Paul; Peggie, Mark; Deak, Maria; Wan, Min; Kaestner, Klaus H.; et al. (Nature communications, 2014)
Keywords: 631/443/319; 631/80/86; 64; 64/60; 692/698/2741/288; 82; 82/1; 82/51; 82/58; 82/80; 96; 96/95; AMP-Activated Protein Kinases; Animals; Clinical Medicine; Endocrinology and Diabetes; Endokrinologi och diabetes; Fasting; Gene Expression Regulation; Glucagon - pharmacology; Gluconeogenesis - drug effects; Gluconeogenesis - genetics; Glucose - metabolism; Hepatocytes - drug effects; Hepatocytes - metabolism; Hepatocytes - pathology; Humanities and Social Sciences; Hyperglycemia - genetics; Hyperglycemia - metabolism; Hyperglycemia - pathology; Insulin; Insulin - metabolism; Klinisk medicin; Liver; Liver - drug effects; Liver - metabolism; Liver - pathology; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Mice; Mice, Knockout; multidisciplinary; Phenylurea Compounds - pharmacology; Phosphorylation - drug effects; Protein Kinase Inhibitors - pharmacology; Protein Serine-Threonine Kinases - deficiency; Protein Serine-Threonine Kinases - genetics; Protein Serine-Threonine Kinases - metabolism; Pyrimidines - pharmacology; Science; Science (multidisciplinary); Signal Transduction; Transcription Factors - genetics; Transcription Factors - metabolism