国产新型电生理刺激反馈仪DS21在无创筛查糖尿病中的初步应用
目的：初步评判国内最新研制的电生理刺激反馈仪DS21无创筛查糖尿病的稳定性、有效性及安全性。方法：46例受试者根据口服葡萄糖耐量试验（OGTT）及既往病史分为健康组（n=17）、糖调节受损组（n=15）和糖尿病组（n=14）。受试者签署知情同意书,接受常规体检及采集病史及生化检查,对受试者进行3次电生理刺激反馈仪DS21测试,得到3个电导值,通过计算平均偏差,判断检测结果的稳定性、有效性,同时观察不良反应。结果：46例受试者电导值平均偏差最大值为4.4,最小值为0.2,均小于5.0;46例受试者中健康组、糖调节受损组和糖尿病组受试者的电导值分别为77.9±5.2、70.4±5.7、54.7±1...
Saved in:
| Published in | 中国临床医学 Vol. 24; no. 3; pp. 359 - 362 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
复旦大学代谢病研究所,上海 200032
2017
复旦大学附属中山医院内分泌科,上海 200032 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1008-6358 |
| DOI | 10.12025/j.issn.1008-6358.2017.20170432 |
Cover
| Abstract | 目的：初步评判国内最新研制的电生理刺激反馈仪DS21无创筛查糖尿病的稳定性、有效性及安全性。方法：46例受试者根据口服葡萄糖耐量试验（OGTT）及既往病史分为健康组（n=17）、糖调节受损组（n=15）和糖尿病组（n=14）。受试者签署知情同意书,接受常规体检及采集病史及生化检查,对受试者进行3次电生理刺激反馈仪DS21测试,得到3个电导值,通过计算平均偏差,判断检测结果的稳定性、有效性,同时观察不良反应。结果：46例受试者电导值平均偏差最大值为4.4,最小值为0.2,均小于5.0;46例受试者中健康组、糖调节受损组和糖尿病组受试者的电导值分别为77.9±5.2、70.4±5.7、54.7±11.4,趋势为健康组〉糖调节受损组〉糖尿病组,组间差异有统计学意义（P〈0.01）;校正了性别、年龄、体质指数（BMI）,3组人群电导值依然存在上述趋势（P〈0.01）。入组受试者均未发生不良事件。结论：国产电生理刺激反馈仪DS21在不同糖代谢人群中存在不同的电导值,有助于评判糖尿病风险,且稳定、安全,值得进一步以应用于临床。 |
|---|---|
| AbstractList | R246.1; 目的:初步评判国内最新研制的电生理刺激反馈仪DS21无创筛查糖尿病的稳定性、有效性及安全性.方法:46例受试者根据口服葡萄糖耐量试验(OGTT)及既往病史分为健康组(n=17)、糖调节受损组(n=15)和糖尿病组(n=14).受试者签署知情同意书,接受常规体检及采集病史及生化检查,对受试者进行3次电生理刺激反馈仪DS21测试,得到3个电导值,通过计算平均偏差,判断检测结果的稳定性、有效性,同时观察不良反应.结果:46例受试者电导值平均偏差最大值为4.4,最小值为0.2,均小于5.0;46例受试者中健康组、糖调节受损组和糖尿病组受试者的电导值分别为77.9±5.2、70.4±5.7、54.7±11.4,趋势为健康组>糖调节受损组>糖尿病组,组间差异有统计学意义(P<0.01);校正了性别、年龄、体质指数(BMI),3组人群电导值依然存在上述趋势(P<0.01).入组受试者均未发生不良事件.结论:国产电生理刺激反馈仪DS21在不同糖代谢人群中存在不同的电导值,有助于评判糖尿病风险,且稳定、安全,值得进一步以应用于临床. 目的：初步评判国内最新研制的电生理刺激反馈仪DS21无创筛查糖尿病的稳定性、有效性及安全性。方法：46例受试者根据口服葡萄糖耐量试验（OGTT）及既往病史分为健康组（n=17）、糖调节受损组（n=15）和糖尿病组（n=14）。受试者签署知情同意书,接受常规体检及采集病史及生化检查,对受试者进行3次电生理刺激反馈仪DS21测试,得到3个电导值,通过计算平均偏差,判断检测结果的稳定性、有效性,同时观察不良反应。结果：46例受试者电导值平均偏差最大值为4.4,最小值为0.2,均小于5.0;46例受试者中健康组、糖调节受损组和糖尿病组受试者的电导值分别为77.9±5.2、70.4±5.7、54.7±11.4,趋势为健康组〉糖调节受损组〉糖尿病组,组间差异有统计学意义（P〈0.01）;校正了性别、年龄、体质指数（BMI）,3组人群电导值依然存在上述趋势（P〈0.01）。入组受试者均未发生不良事件。结论：国产电生理刺激反馈仪DS21在不同糖代谢人群中存在不同的电导值,有助于评判糖尿病风险,且稳定、安全,值得进一步以应用于临床。 |
| Abstract_FL | Objective:To preliminarily assess the stability, effectiveness, and safety of the electrophysiological stimulation feedback instrument DS21 for non-invasive screening diabetes.Methods:Totally 46 cases were selected and divided into health control group (NC,n=17),impaired glucose regulation group(IGR, n=15), and diabetes group (DM, n=14) based on OGTT and diabetic history.All cases signed informed consent, were performed routine check-up and biochemical examination, and collected history, and underwent three times tests by electrophysiological stimulation feedback instrument.Three conductance values of this instrument were recorded for each case, the deviation of average values were calculated, to evaluate its stability and effectiveness, and the adverse reactions were observed.Results:The maximum of the mean conductance value deviation was 4.4, the minimum value was 0.2 in the 46 subjects, which were all less than 5.0, The conductance values were 77.9±5.2,70.4±5.7, and 54.7±11.4 in NC, IGR, and DM group, respectively.The trend of conductance value was NC >IGR > DM group.The difference of conductance values among groups was statistically significant (P<0.01).After adjusting for gender,age, and body mass index (BMI), the difference of conductance values among groups was still statistically significant (P<0.01).There was no adverse event in the test in 46 cases.Conclusions:Electrophysiological stimulation feedback instrument DS21 is stable, reliable.The conductance values are different in subject with different glucose metabolism. |
| Author | 卞华 朱小鹏 颜红梅 常薪霞 夏明锋 高鑫 |
| AuthorAffiliation | 复旦大学附属中山医院内分泌科,上海200032 复旦大学代谢病研究所,上海200032 |
| AuthorAffiliation_xml | – name: 复旦大学附属中山医院内分泌科,上海 200032;复旦大学代谢病研究所,上海 200032 |
| Author_FL | ZHU Xiao-peng BIAN Hua CHANG Xin-xia GAO Xin XIA Ming-feng YAN Hong-mei |
| Author_FL_xml | – sequence: 1 fullname: BIAN Hua – sequence: 2 fullname: ZHU Xiao-peng – sequence: 3 fullname: YAN Hong-mei – sequence: 4 fullname: CHANG Xin-xia – sequence: 5 fullname: XIA Ming-feng – sequence: 6 fullname: GAO Xin |
| Author_xml | – sequence: 1 fullname: 卞华 朱小鹏 颜红梅 常薪霞 夏明锋 高鑫 |
| BookMark | eNo9j89LAkEcxedgkJX_RBdPbt-Z2Z_HsJ8gBOVddscdW7G1XKLs1KFiIaIOi0JWdrEkEIQIwgj_GWeH_osWjS7vHd6H93gLKOXXfRehLAYFEyDaSlXxgsBXMICZ06lmKgSwMRVQKUmh9H8yjzJB4DkAGDSgBNJoV3S-J6PXuDUUT9cy-pBRV95diXAUj8_F7c3PSzj5elvbI1g89OP2swg7ctCJuz353hLDsWxfTj4H8v5ChI_xoCdGkYz6S2iO27XAzfz5IipurBfzW7nCzuZ2frWQY5pl5srMohanhJpcMxkD1QGbM-rqrmNxx3XLjKk2tVRiMW5Qw9Q5s0xH48zmFLCm0kWUndWe2D63_UqpWj9u-Mlg6axSY83T6X-aPE_I5RnJ9ut-5chL2MOGd2A3miXdoBiDTnT6C2aQfks |
| ClassificationCodes | R246.1 |
| ContentType | Journal Article |
| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| Copyright_xml | – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| DBID | 2RA 92L CQIGP W91 ~WA 2B. 4A8 92I 93N PSX TCJ |
| DOI | 10.12025/j.issn.1008-6358.2017.20170432 |
| DatabaseName | 维普_期刊 中文科技期刊数据库-CALIS站点 维普中文期刊数据库 中文科技期刊数据库-医药卫生 中文科技期刊数据库- 镜像站点 Wanfang Data Journals - Hong Kong WANFANG Data Centre Wanfang Data Journals 万方数据期刊 - 香港版 China Online Journals (COJ) China Online Journals (COJ) |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| DocumentTitleAlternate | Preliminary application of new electrophysiological stimulation feedback instrument DS21 in non-invasive screening diabetes |
| DocumentTitle_FL | Preliminary application of new electrophysiological stimulation feedback instrument DS21 in non-invasive screening diabetes |
| EndPage | 362 |
| ExternalDocumentID | zglcyx201703008 673110626 |
| GrantInformation_xml | – fundername: 国家自然科学基金; 上海市卫生和计划生育委员会课题; 上海市科委项目; 复旦大学附属中山医院优秀骨干计划(2015ZSYXGG15).Supported by National Natural Science Foundation of China(81471073) , Shanghai Municipal Commission of Health and Family Planning; Research Project of Science and Technology Commission of Shanghai Municipality; Excellent Member Program of Zhongshan Hospital Fudan University funderid: (81471073); (2013ZYJB0802); (13441900303); (2013ZYJB0802); (13441900303); (2015ZSYXGG15) |
| GroupedDBID | 2RA 92L ALMA_UNASSIGNED_HOLDINGS CDYEO CQIGP W91 ~WA 2B. 4A8 92I 93N PSX TCJ |
| ID | FETCH-LOGICAL-c598-dc939f3238f58cc04b0afc3e6eb9fbeedcc4a39429cf73786fc98b5fcaf301543 |
| ISSN | 1008-6358 |
| IngestDate | Thu May 29 04:08:21 EDT 2025 Wed Feb 14 09:57:18 EST 2024 |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 3 |
| Keywords | 电生理刺激反馈仪 无创诊断 noninvasive diagnosis 糖尿病 diabetes electrophysiological stimulation feedback instrument |
| Language | Chinese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c598-dc939f3238f58cc04b0afc3e6eb9fbeedcc4a39429cf73786fc98b5fcaf301543 |
| Notes | electrophysiological stimulation feedback instrument;diabetes;noninvasive diagnosis 31-1794/R Objective：To preliminarily assess the stability, effectiveness, and safety of the electrophysiological stimulation feedback instrument DS21 for non-invasive screening diabetes.Methods：Totally 46 cases were selected and divided into health control group （NC,n=17）,impaired glucose regulation group（IGR, n=15）, and diabetes group （DM, n=14） based on OGTT and diabetic history.All cases signed informed consent, were performed routine check-up and biochemical examination, and collected history, and underwent three times tests by electrophysiological stimulation feedback instrument.Three conductance values of this instrument were recorded for each case, the deviation of average values were calculated, to evaluate its stability and effectiveness, and the adverse reactions were observed.Results：The maximum of the mean conductance value deviation was 4.4, the minimum value was 0.2 in the 46 subjects, which were all less than 5.0, |
| PageCount | 4 |
| ParticipantIDs | wanfang_journals_zglcyx201703008 chongqing_primary_673110626 |
| PublicationCentury | 2000 |
| PublicationDate | 2017 |
| PublicationDateYYYYMMDD | 2017-01-01 |
| PublicationDate_xml | – year: 2017 text: 2017 |
| PublicationDecade | 2010 |
| PublicationTitle | 中国临床医学 |
| PublicationTitleAlternate | Chinese Journal Of Clinical Medicine |
| PublicationTitle_FL | Chinese Journal of Clinical Medicine |
| PublicationYear | 2017 |
| Publisher | 复旦大学代谢病研究所,上海 200032 复旦大学附属中山医院内分泌科,上海 200032 |
| Publisher_xml | – name: 复旦大学代谢病研究所,上海 200032 – name: 复旦大学附属中山医院内分泌科,上海 200032 |
| SSID | ssib001050320 ssib006562945 ssib036441625 ssib001103563 ssib002262996 ssib008144075 ssib051368386 |
| Score | 2.0857596 |
| Snippet | 目的：初步评判国内最新研制的电生理刺激反馈仪DS21无创筛查糖尿病的稳定性、有效性及安全性。方法：46例受试者根据口服葡萄糖耐量试验（OGTT）及既往病史分为健康... R246.1; 目的:初步评判国内最新研制的电生理刺激反馈仪DS21无创筛查糖尿病的稳定性、有效性及安全性.方法:46例受试者根据口服葡萄糖耐量试验(OGTT)及既往病史分为健康... |
| SourceID | wanfang chongqing |
| SourceType | Aggregation Database Publisher |
| StartPage | 359 |
| SubjectTerms | 无创诊断 电生理刺激反馈仪 糖尿病 |
| Title | 国产新型电生理刺激反馈仪DS21在无创筛查糖尿病中的初步应用 |
| URI | http://lib.cqvip.com/qk/90920A/201703/673110626.html https://d.wanfangdata.com.cn/periodical/zglcyx201703008 |
| Volume | 24 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals issn: 1008-6358 databaseCode: DOA dateStart: 20160101 customDbUrl: isFulltext: true dateEnd: 99991231 titleUrlDefault: https://www.doaj.org/ omitProxy: true ssIdentifier: ssib006562945 providerName: Directory of Open Access Journals |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Na9RAFA-1gngRRcValR4cPKUmmWQyc5zsphRBD1qht5LMblpEtn60oD15UFkQ0cPSglXrpVqEQkEFqUj_mWaD_4XvzWSzQcUvFsJjPt77zXubnd_MzodlnVcuS-ET2EqkMEBppdQWme_aMGJWYerAmMLD_c6Xr7Dp6_6l2WB25MDH2qql5aV0Uq38cl_J_0QV0iCuuEv2HyJbKYUEkCG-8IQIw_OvYkzigIiIRE0S-ySSRIYkZkQwEjk6KyY8InFIBOQGpSCmtOAQzrAM51gRakVTuOgBU0AAhYJIhrmoOSJSNq95rlbaIJJrMyGRTqlCaDOyqQWGNqS2F1FEA2UAUGQMh4QHWinH8pgiCfcHeppYHdKxeoDIALHBLXmdR9c01F0AjfHLilxqnQ1EDwLqrCYhdU4T_WMEHg9zGLYwckvQ4AzwRCRAGBYB13hYChsoUUbMHjGXAg30IxbwE0cHSImVoIaI67MsZjupfiM0RF873niWlSkY0hL9IBQUtQI2NFw5VAfDOEsCYIZ6uMCQeo3SNdzEGaCFeJCkU5_xxcOXbGCFvN5lmW3n5atJa_0PLY9XN1SGmo7up17Sc_SdVze0hcnKAi50DPUDz2kcEoRq2ebK_E11_54uQPUO-4MezoLVJjLMJEMALaiRctehAauTRgYcaEiCYUThidp_2xzXGwxJLUXGzoa9TuBSxqm-wrVCfsi6MGjXxd-3Co9QWVjszN8GYqj36XWypDNfo5QzR60j5VhwQpoX-5g1srJw3Lqar3_d333XX93JXz8pep-K3kbx_HHe3e3vPcifPf32trv_5T2-jPnLrf7am7y7Xmyv9zc2iw-r-c5esfZo__N28eJh3n3V397Md3tFb-uENTMVzzSm7fLiE1sFgtstJajIKJDpLOBKOX7qJJmibdZORZYCqVXKT6gAJqmykIacZUrwNMhUklEcEtGT1mhnsdM-ZU20OK4cdtoqUK6vMpY4rTAMaRKKViJSJcas8codc7fM-Ta41BNixjw2Zk2UDporf_Xuzv3wHTj95yLj1mGUzbzlGWt06c5y-yww-aX0nP7ifAdg477h |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E5%9B%BD%E4%BA%A7%E6%96%B0%E5%9E%8B%E7%94%B5%E7%94%9F%E7%90%86%E5%88%BA%E6%BF%80%E5%8F%8D%E9%A6%88%E4%BB%AADS21%E5%9C%A8%E6%97%A0%E5%88%9B%E7%AD%9B%E6%9F%A5%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E5%88%9D%E6%AD%A5%E5%BA%94%E7%94%A8&rft.jtitle=%E4%B8%AD%E5%9B%BD%E4%B8%B4%E5%BA%8A%E5%8C%BB%E5%AD%A6&rft.au=%E5%8D%9E%E5%8D%8E&rft.au=%E6%9C%B1%E5%B0%8F%E9%B9%8F&rft.au=%E9%A2%9C%E7%BA%A2%E6%A2%85&rft.au=%E5%B8%B8%E8%96%AA%E9%9C%9E&rft.date=2017&rft.pub=%E5%A4%8D%E6%97%A6%E5%A4%A7%E5%AD%A6%E4%BB%A3%E8%B0%A2%E7%97%85%E7%A0%94%E7%A9%B6%E6%89%80%2C%E4%B8%8A%E6%B5%B7+200032&rft.issn=1008-6358&rft.volume=24&rft.issue=3&rft.spage=359&rft.epage=362&rft_id=info:doi/10.12025%2Fj.issn.1008-6358.2017.20170432&rft.externalDocID=zglcyx201703008 |
| thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fimage.cqvip.com%2Fvip1000%2Fqk%2F90920A%2F90920A.jpg http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fzglcyx%2Fzglcyx.jpg |