不同时机营养干预在化疗后Ⅳ度骨髓抑制肿瘤患者中的疗效比较

目的回顾性分析探讨并比较不同时机营养治疗在化疗后Ⅳ度骨髓抑制肿瘤患者中的优劣性。方法回顾性分析两组(早期营养干预组和晚期营养干预组)化疗后Ⅳ度骨髓抑制的患者,比较两组患者在粒细胞、血小板等上升时间,合并细菌、真菌感染的比例,死亡率等的差异。结果早期干预组在白细胞、血小板等开始上升时间(4.8±1.8)、(7.6±2.2)早于晚期营养干预组(7.2±2.5)、(12.2±3.1),且早期营养干预组细菌、真菌感染发生率及死亡率(17.10%、9.21%、3.94%)等亦低于晚期营养干预组(42.85%、26.98%、12.70%)。结论早期积极营养支持不仅有利于缩短白细胞等恢复时间,而且可以减少感...

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Published in肿瘤防治研究 Vol. 45; no. 1; pp. 29 - 31
Main Author 齐晓光;祁春艳;秦博宇;王李杰;胡毅
Format Journal Article
LanguageChinese
Published 解放军总医院肿瘤内一科 100853 北京%解放军总医院国宾一科 100853 北京 2018
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ISSN1000-8578
DOI10.3971/j.issn.1000-8578.2018.17.0715

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Summary:目的回顾性分析探讨并比较不同时机营养治疗在化疗后Ⅳ度骨髓抑制肿瘤患者中的优劣性。方法回顾性分析两组(早期营养干预组和晚期营养干预组)化疗后Ⅳ度骨髓抑制的患者,比较两组患者在粒细胞、血小板等上升时间,合并细菌、真菌感染的比例,死亡率等的差异。结果早期干预组在白细胞、血小板等开始上升时间(4.8±1.8)、(7.6±2.2)早于晚期营养干预组(7.2±2.5)、(12.2±3.1),且早期营养干预组细菌、真菌感染发生率及死亡率(17.10%、9.21%、3.94%)等亦低于晚期营养干预组(42.85%、26.98%、12.70%)。结论早期积极营养支持不仅有利于缩短白细胞等恢复时间,而且可以减少感染的发生率、死亡率等。
Bibliography:42-1241/R
QI Xiaoguang1, QI Chunyan2, QIN Boyu1, WANG Lijie1, HU Yi1( 1.Department of Oncology, Chinese PLA General Hospital, Beijing 100853, China, 2. Department of Special Ward, Chinese PLA General Hospital, Beijing 100853, China)
Myelosuppression; Nutritional support; Comparative study; Chemotherapy
Objective To explore and evaluate the effect of different time nutrition intervention on chemotherapy-induced IV degree myelosuppression in cancer patients. Methods A retrospective analysis was conducted on two groups of caner patients with chemotherapy-induced IV degree myelosuppression. The early nutritional intervention group: patients received nutritional intervention within 72 hours after diagnosis of IV degree myelosuppression; in contrast, the other group was set as the late nutrition intervention group. We investigated and compared the difference between the two groups in the rising time of leukocyte and platelet, bacterial infection rates, fungal infection rates and mortality rates. Results In the early n
ISSN:1000-8578
DOI:10.3971/j.issn.1000-8578.2018.17.0715