正五聚素蛋白3的功能研究进展

正五聚素蛋白3(pentraxin 3,PTX3)是第一个被识别的长链五聚素,在先天性体液免疫中发挥重要作用。本文分别从抑制病原体感染、抗动脉粥样硬化和参与中枢神经系统急慢性疾病等3个方面对PTX3的功能进行了综述,以期对其进一步的研究提供思路。...

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Bibliographic Details
Published in中国卒中杂志 Vol. 11; no. 10; pp. 894 - 896
Main Author 易立 郭芳
Format Journal Article
LanguageChinese
Published 100050,北京首都医科大学附属北京友谊医院神经内科 2016
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ISSN1673-5765
DOI10.3969/j.issn.1673-5765.2016.10.015

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Summary:正五聚素蛋白3(pentraxin 3,PTX3)是第一个被识别的长链五聚素,在先天性体液免疫中发挥重要作用。本文分别从抑制病原体感染、抗动脉粥样硬化和参与中枢神经系统急慢性疾病等3个方面对PTX3的功能进行了综述,以期对其进一步的研究提供思路。
Bibliography:11-5434/R
Pentraxin 3; Infection; Atherosclerosis; Central nervous system
YI Li, GUO Fang. (Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)
Pentraxin 3(PTX3) is the first identified long chain five polymer structure protein, which plays an important role in innate humoral immunity. This paper reviewed the function of PTX3 in three aspects, including inhibiting pathogen infection, resisting arteriosclerosis and participating in acute and chronic diseases of the central nervous system, so as to provide ideas for further research.
ISSN:1673-5765
DOI:10.3969/j.issn.1673-5765.2016.10.015