血浆可溶性P-选择素在原发性肝癌患者中的临床意义

R735.7; 探讨血浆可溶性P-选择素(sP-selectin)在原发性肝癌患者中的临床意义.应用ELISA法检测139例原发性肝癌患者血浆sP-selectin的水平.原发性肝癌患者血浆sP-selectin含量明显高于正常对照组(P＜0.01),其中临床Ⅱ期患者高于临床Ⅰ期患者,而临床Ⅲ期患者又高于临床Ⅱ期患者.术后第15d,患者血浆sP-selectin含量较术前明显降低(P＜0.01),但仍明显高于正常对照组(P＜0.01).术后第30d,患者血浆sP-selectin含量较术后第15d进一步降低(P＜0.01),与正常对照组比较差异无显著性(P＞0.05).提示原发性肝癌患者血浆s...

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Published in临床肝胆病杂志 Vol. 19; no. 1; pp. 54 - 55
Main Authors 刘剑勇, 张力图, 张春燕, 覃宇周, 吴飞翔, 唐朝晖, 李挺, 杨南武
Format Journal Article
LanguageChinese
Published 广西医科大学附属肿瘤医院普瘤外科,南宁,530021%广西医科大学附属肿瘤医院分子生物学研究室,南宁,530021 2003
Subjects
原发性肝癌
可溶性p-选择素
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ISSN1001-5256
DOI10.3969/j.issn.1001-5256.2003.01.027

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Abstract R735.7; 探讨血浆可溶性P-选择素(sP-selectin)在原发性肝癌患者中的临床意义.应用ELISA法检测139例原发性肝癌患者血浆sP-selectin的水平.原发性肝癌患者血浆sP-selectin含量明显高于正常对照组(P＜0.01),其中临床Ⅱ期患者高于临床Ⅰ期患者,而临床Ⅲ期患者又高于临床Ⅱ期患者.术后第15d,患者血浆sP-selectin含量较术前明显降低(P＜0.01),但仍明显高于正常对照组(P＜0.01).术后第30d,患者血浆sP-selectin含量较术后第15d进一步降低(P＜0.01),与正常对照组比较差异无显著性(P＞0.05).提示原发性肝癌患者血浆sP-selectin水平明显高于正常人,而且其水平与病情呈正相关.手术切除肝癌可降低患者血浆sP-selectin水平.血浆sP-selectin的检测及动态观察可能对原发性肝癌的辅助诊断、病情发展的判断、疗效观察以及预后估计具有一定的临床意义.
AbstractList R735.7; 探讨血浆可溶性P-选择素(sP-selectin)在原发性肝癌患者中的临床意义.应用ELISA法检测139例原发性肝癌患者血浆sP-selectin的水平.原发性肝癌患者血浆sP-selectin含量明显高于正常对照组(P＜0.01),其中临床Ⅱ期患者高于临床Ⅰ期患者,而临床Ⅲ期患者又高于临床Ⅱ期患者.术后第15d,患者血浆sP-selectin含量较术前明显降低(P＜0.01),但仍明显高于正常对照组(P＜0.01).术后第30d,患者血浆sP-selectin含量较术后第15d进一步降低(P＜0.01),与正常对照组比较差异无显著性(P＞0.05).提示原发性肝癌患者血浆sP-selectin水平明显高于正常人,而且其水平与病情呈正相关.手术切除肝癌可降低患者血浆sP-selectin水平.血浆sP-selectin的检测及动态观察可能对原发性肝癌的辅助诊断、病情发展的判断、疗效观察以及预后估计具有一定的临床意义.
Author 刘剑勇
李挺
张春燕
吴飞翔
唐朝晖
杨南武
覃宇周
张力图
AuthorAffiliation 广西医科大学附属肿瘤医院普瘤外科,南宁,530021%广西医科大学附属肿瘤医院分子生物学研究室,南宁,530021
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可溶性p-选择素
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Snippet R735.7; 探讨血浆可溶性P-选择素(sP-selectin)在原发性肝癌患者中的临床意义.应用ELISA法检测139例原发性肝癌患者血浆sP-selectin的水平.原发性肝癌患者血浆sP-selectin含...
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Title 血浆可溶性P-选择素在原发性肝癌患者中的临床意义
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