Presenilin-1 influences processing of the acetylcholinesterase membrane anchor PRiMA - García-Ayllón, María-Salud; Campanari, María-Letizia; Montenegro, María-Fernanda; Cuchillo-Ibáñez, Inmaculada; Belbin, Olivia; Lleó, Alberto; Tsim, Karl; Vidal, Cecilio J.; Sáez-Valero, Javier (Neurobiology of aging, 2014)
Keywords: Acetylcholinesterase; Acetylcholinesterase - metabolism; Acetylcholinesterase - physiology; Acetylcholinesterase - therapeutic use; Alzheimer Disease - drug therapy; Alzheimer Disease - etiology; Alzheimer's disease; Amyloid Precursor Protein Secretases - physiology; Amyloid Precursor Protein Secretases - therapeutic use; Animals; Brain - enzymology; Brain - metabolism; Cell Nucleus - enzymology; Cells, Cultured; Cricetinae; Drug Design; Female; Gene Expression - genetics; Internal Medicine; Membrane Microdomains - metabolism; Membrane Proteins - genetics; Membrane Proteins - metabolism; Mice; Mice, Knockout; Molecular Targeted Therapy; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Neurology; Presenilin 1; Presenilin-1 - physiology; PRiMA; γ-Secretase; Acetylcholinesterase; Presenilin 1; PRiMA; Alzheimer's disease; γ-Secretase