Full-length 16S rRNA Sequencing Reveals Gut Microbiome Signatures Predictive of MASLD in children with obesity - Lin, Yu-Cheng; Wu, Chi-Chien; Li, Yun-Er; Chen, Chun-Liang; Lin, Chia-Ray; Ni, Yen-Hsuan (BMC microbiology, 2025)
Keywords: 16S rRNA; Accuracy; Adolescent; Alanine; Alanine transaminase; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Bar codes; Biological Microscopy; Biomarkers; Biomedical and Life Sciences; Body mass index; Case-Control Studies; Child; Children; Cholesterol; Complications and side effects; Composition; Development and progression; Discriminant analysis; DNA, Bacterial - genetics; Fatty liver; Fatty Liver - microbiology; Feces; Feces - microbiology; Female; Gastrointestinal Microbiome - genetics; Gene amplification; Genetic aspects; Gut microbiota; Health aspects; High-Throughput Nucleotide Sequencing; Homeostasis; Humans; Insulin resistance; Intestinal microflora; Life Sciences; Liver diseases; Male; MASLD; Metabolic diseases; Metabolism; Microbiology; Microbiomes; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Mycology; Next-generation sequencing; Obesity; Obesity - complications; Obesity - microbiology; Obesity in children; Parasitology; Pediatric Obesity - complications; Pediatric Obesity - microbiology; Pediatric research; Performance evaluation; Prediction models; Random forest; Risk factors; RNA sequencing; RNA, Ribosomal, 16S - genetics; rRNA 16S; Sequence Analysis, DNA; Sequencing; Taxonomy; Triglycerides; Virology; Taiwan; Germany; Gut microbiota; 16S rRNA; Random forest; MASLD; Sequencing